Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function.

[1]  C. Klaver,et al.  Comprehensive analysis of the achromatopsia genes CNGA3 and CNGB3 in progressive cone dystrophy. , 2010, Ophthalmology.

[2]  Andreas Wenzel,et al.  Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography , 2009, PloS one.

[3]  K. Palczewski,et al.  Focus on molecules: guanylate cyclase-activating proteins (GCAPs). , 2009, Experimental eye research.

[4]  C. Klaver,et al.  Genetic etiology and clinical consequences of complete and incomplete achromatopsia. , 2009, Ophthalmology.

[5]  W. Hauswirth,et al.  High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[6]  M. Ueffing,et al.  PKG activity causes photoreceptor cell death in two retinitis pigmentosa models , 2009, Journal of neurochemistry.

[7]  W. Hauswirth,et al.  Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial. , 2008, Human gene therapy.

[8]  Edwin M Stone,et al.  Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics , 2008, Proceedings of the National Academy of Sciences.

[9]  K. Yau,et al.  How vision begins: An odyssey , 2008, Proceedings of the National Academy of Sciences.

[10]  E. Traboulsi,et al.  CNGA3 mutations in two United Arab Emirates families with achromatopsia , 2008, Molecular vision.

[11]  Nick Tyler,et al.  Effect of gene therapy on visual function in Leber's congenital amaurosis. , 2008, The New England journal of medicine.

[12]  Kathleen A. Marshall,et al.  Safety and efficacy of gene transfer for Leber's congenital amaurosis. , 2008, The New England journal of medicine.

[13]  K. Palczewski,et al.  Trafficking of Membrane-Associated Proteins to Cone Photoreceptor Outer Segments Requires the Chromophore 11-cis-Retinal , 2008, The Journal of Neuroscience.

[14]  W. Baehr,et al.  A model for transport of membrane-associated phototransduction polypeptides in rod and cone photoreceptor inner segments , 2008, Vision Research.

[15]  C. Mussolino,et al.  Novel Adeno-Associated Virus Serotypes Efficiently Transduce Murine Photoreceptors , 2007, Journal of Virology.

[16]  P. Sieving,et al.  CNGB3 achromatopsia with progressive loss of residual cone function and impaired rod-mediated function. , 2007, Investigative ophthalmology & visual science.

[17]  W. Hauswirth,et al.  Restoration of cone vision in a mouse model of achromatopsia , 2007, Nature Medicine.

[18]  G. H. Jacobs,et al.  Emergence of Novel Color Vision in Mice Engineered to Express a Human Cone Photopigment , 2007, Science.

[19]  A. Milam,et al.  Cone photoreceptor function loss-3, a novel mouse model of achromatopsia due to a mutation in Gnat2. , 2006, Investigative ophthalmology & visual science.

[20]  J. Grieger,et al.  Production and characterization of adeno-associated viral vectors , 2006, Nature Protocols.

[21]  Andreas Wenzel,et al.  In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy , 2005, Vision Research.

[22]  S. Deeb,et al.  The molecular basis of variation in human color vision , 2005, Clinical genetics.

[23]  H. Wässle,et al.  The Primordial, Blue-Cone Color System of the Mouse Retina , 2005, The Journal of Neuroscience.

[24]  S. Haverkamp,et al.  Impaired opsin targeting and cone photoreceptor migration in the retina of mice lacking the cyclic nucleotide-gated channel CNGA3. , 2005, Investigative ophthalmology & visual science.

[25]  P. Sieving,et al.  CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia , 2005, European Journal of Human Genetics.

[26]  K. Yau,et al.  Impaired Channel Targeting and Retinal Degeneration in Mice Lacking the Cyclic Nucleotide-Gated Channel Subunit CNGB1 , 2005, The Journal of Neuroscience.

[27]  G. H. Jacobs,et al.  Influence of cone pigment coexpression on spectral sensitivity and color vision in the mouse , 2004, Vision Research.

[28]  M. Varnum,et al.  Subunit Configuration of Heteromeric Cone Cyclic Nucleotide-Gated Channels , 2004, Neuron.

[29]  G. Jung,et al.  Immunocytochemical localization of glycogen phosphorylase isozymes in rat nervous tissues by using isozyme‐specific antibodies , 2003, Journal of neurochemistry.

[30]  S. Jacobson,et al.  Mutations in the cone photoreceptor G-protein alpha-subunit gene GNAT2 in patients with achromatopsia. , 2002, American journal of human genetics.

[31]  B. Wissinger,et al.  Clinical features of achromatopsia in Swedish patients with defined genotypes , 2002, Ophthalmic genetics.

[32]  C. Grimm,et al.  New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis , 2001, Nature Genetics.

[33]  Lili Wang,et al.  Hybrid Vectors Based on Adeno-Associated Virus Serotypes 2 and 5 for Muscle-Directed Gene Transfer , 2001, Journal of Virology.

[34]  Jean Bennett,et al.  Gene therapy restores vision in a canine model of childhood blindness , 2001, Nature Genetics.

[35]  M. Seeliger,et al.  Evaluation of the rhodopsin knockout mouse as a model of pure cone function. , 2001, Investigative ophthalmology & visual science.

[36]  D. Hunt,et al.  Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy , 2000, Nature Genetics.

[37]  M. Seeliger,et al.  Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[38]  G H Jacobs,et al.  Human Cone Pigment Expressed in Transgenic Mice Yields Altered Vision , 1999, The Journal of Neuroscience.

[39]  S. Jacobson,et al.  Total colourblindness is caused by mutations in the gene encoding the α-subunit of the cone photoreceptor cGMP-gated cation channel , 1998, Nature Genetics.

[40]  J. de Vente,et al.  Nitric oxide‐mediated cGMP synthesis in oligodendrocytes in the developing rat brain , 1997, Glia.

[41]  P. Sieving,et al.  Retinopathy induced in mice by targeted disruption of the rhodopsin gene , 1997, Nature Genetics.

[42]  N. Tanimoto,et al.  Vision tests in the mouse: Functional phenotyping with electroretinography. , 2009, Frontiers in bioscience.

[43]  A. Swaroop,et al.  Transgenic Mice Expressing Cre-recombinase Specifically in M-or S-cone Photoreceptors and Anand Swaroop Materials and Methods , 2022 .

[44]  Lindsay T Sharpe,et al.  The molecular basis of dichromatic color vision in males with multiple red and green visual pigment genes. , 2002, Human molecular genetics.

[45]  James M. Wilson,et al.  Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column. , 2001, Human gene therapy.