A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion

[1]  A. Salmina,et al.  Plasticity of Adipose Tissue-Derived Stem Cells and Regulation of Angiogenesis , 2018, Front. Physiol..

[2]  M. Mohammadi,et al.  Faculty Opinions recommendation of Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. , 2018, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

[3]  M. Kumari,et al.  Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity. , 2018, Cell metabolism.

[4]  Tiffany DeSouza,et al.  Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells , 2018, bioRxiv.

[5]  P. Scherer,et al.  VEGF-A–Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4–Independent Metabolic Improvements , 2017, Diabetes.

[6]  J. Graff,et al.  Emerging Roles of Adipose Progenitor Cells in Tissue Development, Homeostasis, Expansion and Thermogenesis , 2016, Trends in Endocrinology & Metabolism.

[7]  K. Alitalo,et al.  VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications. , 2016, Cell metabolism.

[8]  May-yun Wang,et al.  Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice. , 2016, Cell metabolism.

[9]  J. Graff,et al.  Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function , 2016, Nature Communications.

[10]  Zhiyu Zhao,et al.  Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal , 2015, Nature.

[11]  B. Öksüzoğlu,et al.  Sunitinib-induced severe hypoglycemia in a diabetic patient , 2014, Journal of Oncology Pharmacy Practice.

[12]  J. Graff,et al.  Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis. , 2014, Cell reports.

[13]  N. Noy,et al.  Holo-retinol-binding protein and its receptor STRA6 drive oncogenic transformation. , 2014, Cancer research.

[14]  P. Rojas-Ríos,et al.  Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair , 2014, Stem cells.

[15]  A. Herman,et al.  Inhibition of c-Kit Is Not Required for Reversal of Hyperglycemia by Imatinib in NOD Mice , 2014, PloS one.

[16]  S. Morrison,et al.  The bone marrow niche for haematopoietic stem cells , 2014, Nature.

[17]  Panteleimon Rompolas,et al.  Spatial organization within a niche as a determinant of stem cell fate , 2013, Nature.

[18]  J. Graff,et al.  The developmental origins of adipose tissue , 2013, Development.

[19]  P. Scherer,et al.  Tracking adipogenesis during white adipose tissue development, expansion and regeneration , 2013, Nature Medicine.

[20]  J. Graff,et al.  SnapShot: Adipocyte Life Cycle , 2012, Cell.

[21]  M. Breccia,et al.  Fasting glucose level reduction induced by imatinib in chronic myeloproliferative disease with TEL-PDGFRβ rearrangement and type 1 diabetes , 2012, Annals of Hematology.

[22]  N. Noy,et al.  Retinoic Acid Upregulates Preadipocyte Genes to Block Adipogenesis and Suppress Diet-Induced Obesity , 2012, Diabetes.

[23]  J. Graff,et al.  Wnt signaling activation in adipose progenitors promotes insulin-independent muscle glucose uptake. , 2012, Cell metabolism.

[24]  G. Semenza,et al.  Hypoxia-Inducible Factors in Physiology and Medicine , 2012, Cell.

[25]  M. Kyba,et al.  Inducible Cassette Exchange: A Rapid and Efficient System Enabling Conditional Gene Expression in Embryonic Stem and Primary Cells , 2011, Stem cells.

[26]  C. Lynch,et al.  Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice , 2011, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.

[27]  P. Hauschka,et al.  Adipose stem cells originate from perivascular cells , 2011, Biology of the cell.

[28]  C. Betsholtz,et al.  Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. , 2011, Developmental cell.

[29]  J. Graff,et al.  Thiazolidinediones regulate adipose lineage dynamics. , 2011, Cell metabolism.

[30]  Philippe Soriano,et al.  PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. , 2011, Developmental cell.

[31]  C. Betsholtz,et al.  Pericytes and the blood-brain barrier: recent advances and implications for the delivery of CNS therapy. , 2011, Therapeutic delivery.

[32]  H. Clevers,et al.  Tissue-resident adult stem cell populations of rapidly self-renewing organs. , 2010, Cell stem cell.

[33]  B. Desvergne,et al.  PPARgamma in placental angiogenesis. , 2010, Endocrinology.

[34]  S. Morrison,et al.  An in vivo model to study and manipulate the hematopoietic stem cell niche. , 2010, Blood.

[35]  Zev Rosenwaks,et al.  Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. , 2009, Cell stem cell.

[36]  P. Chambon,et al.  Efficient temporally‐controlled targeted mutagenesis in smooth muscle cells of the adult mouse , 2009, Genesis.

[37]  R. Hammer,et al.  White Fat Progenitor Cells Reside in the Adipose Vasculature , 2008, Science.

[38]  J. García-Verdugo,et al.  A specialized vascular niche for adult neural stem cells. , 2008, Cell stem cell.

[39]  S. Corvera,et al.  Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production. , 2008, American journal of physiology. Endocrinology and metabolism.

[40]  Peter Tontonoz,et al.  Fat and beyond: the diverse biology of PPARgamma. , 2008, Annual review of biochemistry.

[41]  E. Gaetani,et al.  Selective Activation of Peroxisome Proliferator–Activated Receptor (PPAR)α and PPARγ Induces Neoangiogenesis Through a Vascular Endothelial Growth Factor–Dependent Mechanism , 2008, Diabetes.

[42]  Sean J. Morrison,et al.  Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life , 2008, Cell.

[43]  S. Morrison,et al.  Maintaining hematopoietic stem cells in the vascular niche. , 2006, Immunity.

[44]  Jill M Seargent,et al.  GW9662, a potent antagonist of PPARγ, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARγ agonist rosiglitazone, independently of PPARγ activation , 2004, British journal of pharmacology.

[45]  F. Mandelli,et al.  Imatinib mesylate may improve fasting blood glucose in diabetic Ph+ chronic myelogenous leukemia patients responsive to treatment. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[46]  W. Wahli,et al.  The Direct Peroxisome Proliferator-activated Receptor Target Fasting-induced Adipose Factor (FIAF/PGAR/ANGPTL4) Is Present in Blood Plasma as a Truncated Protein That Is Increased by Fenofibrate Treatment* , 2004, Journal of Biological Chemistry.

[47]  Philippe Soriano,et al.  Additive Effects of PDGF Receptor β Signaling Pathways in Vascular Smooth Muscle Cell Development , 2003, PLoS biology.

[48]  C. Handschin,et al.  NUBIScan, an in silico approach for prediction of nuclear receptor response elements. , 2002, Molecular endocrinology.

[49]  P. Carmeliet,et al.  A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects. , 2001, Development.

[50]  R. Hammer,et al.  Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. , 2001, Developmental biology.

[51]  任艳,et al.  胰岛素增敏剂一Thiazolidinediones研究现状 , 2000 .

[52]  P. Chambon,et al.  Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene* , 2000, The Journal of Biological Chemistry.

[53]  I. Weissman,et al.  Stem Cells Units of Development, Units of Regeneration, and Units in Evolution , 2000, Cell.

[54]  G. Mcmahon,et al.  Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases. , 1999, Journal of medicinal chemistry.

[55]  K. Chien,et al.  PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development , 1999 .

[56]  A. Whetton,et al.  Homing and mobilization in the stem cell niche. , 1999, Trends in cell biology.

[57]  K. Umesono,et al.  Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. , 1998, The Journal of clinical investigation.

[58]  Philippe Soriano,et al.  Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. , 1994, Genes & development.

[59]  B. Spiegelman,et al.  mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. , 1994, Genes & development.

[60]  M. Lazar,et al.  Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[61]  C. Heldin,et al.  Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[62]  M. M. Copeland.  Recent Results in Cancer Research, Fortschritte der Krebsforschung Progrès dans les Recherches sur le Cancer, Vol 13, Tumours in Children. , 1969 .

[63]  C. Waller,et al.  Imatinib mesylate. , 2010, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

[64]  Nuclear Receptor BioMed Central , 2005 .

[65]  R. Evans,et al.  PPAR gamma is required for placental, cardiac, and adipose tissue development. , 1999, Molecular cell.

[66]  T. Meyer,et al.  Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. , 1996, Cancer research.

[67]  R. Schofield.  The relationship between the spleen colony-forming cell and the haemopoietic stem cell. , 1978, Blood cells.