Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2).
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S. Spergel | K. McIntyre | J. Tokarski | D. Xie | N. Araníbar | L. Lombardo | P. Carter | Stephen T. Wrobleski | J. Strnad | C. D’arienzo | S. Lin | J. Muckelbauer | Xiaoxia Yang | R. Moslin | Lihong Cheng | M. Chiney | A. Zupa-Fernandez | J. Tredup | Chiehying J Chang | Dawn Mulligan | D. Weinstein | James R. Burke | Elizabeth M. Heimrich | Kathleen M. Gillooly | Michael E. Mertzman | Charu Chaudhry | Yanlei Zhang | Huadong Sun | Christine Huang