Running title: p97/VCP and gp78 interaction in ERAD

Abbreviations used are: AAA ATPase: ATPase associated with various cellular activities; VCP: valosin-containing protein; ER: endoplasmic reticulum; ERAD: ERassociated degradation; NZF: Npl4 zinc finger; UBA domain: Ubiquitin-associated domain; GST: glutathione S-transferase; HA: hemagglutinin; IB: immunoblotting; IP: immunoprecipitation; RNAi: RNA interference; siRNA: small interference RNA; RING: really interesting new gene; GFP: green fluorescent protein JBC Papers in Press. Published on September 1, 2004 as Manuscript M409034200