OPTIMALITY CRITERIA FOR MULTIRESPONSE LINEAR MODELS BASED ON PREDICTIVE ELLIPSOIDS

This paper proposes a new class of optimum design criteria for the linear regression model with r responses based on the volume of the predictive ellipsoid. This is referred to as I r L-optimality. The I r L-optimality criterion is invariant with respect to different parameterizations of the model, and reduces to IL-optimality as proposed by Dette and O'Brien (1999) in single response situations. An equivalence theorem for I r L-optimality is provided and used to verify I r L-optimality of designs,