Progress and problems in the application of focused ultrasound for blood-brain barrier disruption.
暂无分享,去创建一个
Natalia Vykhodtseva | Kullervo Hynynen | Nathan McDannold | K. Hynynen | N. McDannold | N. Vykhodtseva
[1] Kullervo Hynynen,et al. Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. , 2008, Ultrasound in medicine & biology.
[2] K. Hynynen,et al. Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. , 2008, Ultrasound in medicine & biology.
[3] K. Hynynen,et al. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. , 2008, Ultrasound in medicine & biology.
[4] N. Vykhodtseva,et al. 6A-4 Focused Ultrasound Potential to Initiate Spreading Depression for Disruption of Blood Brain Barrier , 2007, 2007 IEEE Ultrasonics Symposium Proceedings.
[5] Kullervo Hynynen,et al. Cavitation threshold of microbubbles in gel tunnels by focused ultrasound. , 2007, Ultrasound in medicine & biology.
[6] Natalia Vykhodtseva,et al. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI‐guided focused ultrasound , 2007, International journal of cancer.
[7] D. Salvadori,et al. Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats. , 2007, Mutation research.
[8] G. Mantovani,et al. A multicenter phase II study of pegylated liposomal doxorubicin and oxaliplatin in recurrent ovarian cancer. , 2007, Gynecologic oncology.
[9] S. Pignata,et al. A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) group , 2007, British Journal of Cancer.
[10] N. Pimpinelli,et al. Pegylated liposomal doxorubicin in the treatment of primary cutaneous T-cell lymphomas. , 2007, Haematologica.
[11] M. Gilbert,et al. Molecularly targeted therapies for malignant gliomas: advances and challenges , 2007, Expert review of anticancer therapy.
[12] K. Itoh,et al. Peptide-based immunotherapeutic approaches to glioma: a review , 2007, Expert opinion on biological therapy.
[13] K. Hynynen,et al. Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study. , 2007, Ultrasound in medicine & biology.
[14] R. Berardi,et al. Chemotherapy for advanced gastric cancer: across the years for a standard of care , 2007, Expert opinion on pharmacotherapy.
[15] M. Lesniak,et al. Convection enhanced drug delivery of novel therapeutic agents to malignant brain tumors. , 2007, Current drug delivery.
[16] D. Gerber,et al. Emerging monoclonal antibody therapies for malignant gliomas , 2007, Expert opinion on investigational drugs.
[17] G. Takemura,et al. Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management. , 2007, Progress in cardiovascular diseases.
[18] G. von Minckwitz. Docetaxel/anthracycline combinations for breast cancer treatment , 2007, Expert opinion on pharmacotherapy.
[19] K. Hynynen,et al. Modular design for in vivo optical imaging and ultrasound treatment in the murine brain , 2007, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.
[20] K. Hynynen,et al. Multiphoton Imaging of Ultrasound/Optison Mediated Cerebrovascular Effects in vivo , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[21] Bhawna Gupta,et al. Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice , 2007, Cancer Immunology, Immunotherapy.
[22] W. Scheithauer,et al. Phase II trial of pegylated liposomal doxorubicin (Caelyx™) plus Gemcitabine in chemotherapeutically pretreated patients with advanced breast cancer , 2007, Acta oncologica.
[23] C. Palmieri,et al. AIDS-related non-Hodgkin's lymphoma in the first decade of highly active antiretroviral therapy. , 2006, QJM : monthly journal of the Association of Physicians.
[24] Yi Ai,et al. Point source concentration of GDNF may explain failure of phase II clinical trial , 2006, Experimental Neurology.
[25] Katherine W Ferrara,et al. Acoustic response of compliable microvessels containing ultrasound contrast agents , 2006, Physics in medicine and biology.
[26] O. Hamill,et al. Twenty odd years of stretch-sensitive channels , 2006, Pflügers Archiv.
[27] Y. Tabata,et al. Local delivery of doxorubicin for malignant glioma by a biodegradable PLGA polymer sheet. , 2006, Anticancer research.
[28] Kullervo Hynynen,et al. Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier. , 2006, Ultrasound in medicine & biology.
[29] T. Wallimann,et al. New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics. , 2006, Journal of molecular and cellular cardiology.
[30] Natalia Vykhodtseva,et al. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. , 2006, Journal of neurosurgery.
[31] D D Allen,et al. The blood-brain barrier and brain drug delivery. , 2006, Journal of nanoscience and nanotechnology.
[32] R. Livingston,et al. Capecitabine therapy for refractory metastatic thyroid carcinoma: a case series. , 2006, Thyroid : official journal of the American Thyroid Association.
[33] W. Pardridge. Molecular Trojan horses for blood-brain barrier drug delivery. , 2006, Discovery medicine.
[34] Kullervo Hynynen,et al. Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain--a primate study. , 2006, European journal of radiology.
[35] Manabu Kinoshita,et al. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[36] N. Vykhodtseva,et al. Steady Potential Changes and Spreading Depression in Rat Brains Produced by Focused Ultrasound , 2006 .
[37] W. Hall,et al. Osmotic blood–brain barrier disruption chemotherapy for diffuse pontine gliomas , 2006, Journal of Neuro-Oncology.
[38] Jianying Cui,et al. Bubble pulsations between parallel plates. , 2006, The Journal of the Acoustical Society of America.
[39] A. Jemal,et al. Cancer Statistics, 2006 , 2006, CA: a cancer journal for clinicians.
[40] K. Hynynen,et al. Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. , 2006, Biochemical and biophysical research communications.
[41] K. Hynynen,et al. Targeted disruption of the blood–brain barrier with focused ultrasound: association with cavitation activity , 2006, Physics in medicine and biology.
[42] Paul A. Dayton,et al. Microbubble oscillation in tubes with diameters of 12, 25, and 195 microns , 2006 .
[43] S. Roman,et al. Adrenocortical carcinoma , 2006, Current opinion in oncology.
[44] E. Winer,et al. Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy. , 2005, Annals of oncology : official journal of the European Society for Medical Oncology.
[45] Natalia Vykhodtseva,et al. MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. , 2005, Ultrasound in medicine & biology.
[46] I. Nagata,et al. Induced Spreading Depression Activates Persistent Neurogenesis in the Subventricular Zone, Generating Cells With Markers for Divided and Early Committed Neurons in the Caudate Putamen and Cortex , 2005, Stroke.
[47] Kullervo Hynynen,et al. A numerical study of transcranial focused ultrasound beam propagation at low frequency , 2005, Physics in medicine and biology.
[48] W. K. Cullen,et al. Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo , 2005, Nature Medicine.
[49] M. Dietlein,et al. Imaging of central nervous system lymphomas with iodine‐123 labeled rituximab , 2005, European journal of haematology.
[50] C. Milstein,et al. Pillars Article: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature, 1975, 256 (5517): 495–497. , 2005 .
[51] Ferenc A. Jolesz,et al. Local and reversible blood–brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications , 2005, NeuroImage.
[52] M. Mayberg,et al. The cerebral vasculature as a therapeutic target for neurological disorders and the role of shear stress in vascular homeostatis and pathophysiology , 2004, Neurological research.
[53] Wen-Zhi Chen,et al. Extracorporeal High Intensity Focused Ultrasound Ablation in the Treatment of Patients with Large Hepatocellular Carcinoma , 2004, Annals of Surgical Oncology.
[54] M Mazumdar,et al. Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. , 2004, Annals of oncology : official journal of the European Society for Medical Oncology.
[55] Gunnar P. H. Dietz,et al. Delivery of bioactive molecules into the cell: the Trojan horse approach , 2004, Molecular and Cellular Neuroscience.
[56] Geoffrey S Ginsburg,et al. Targeted therapies for cancer 2004. , 2004, American journal of clinical pathology.
[57] Kenichi Murao,et al. Spreading depression induces long-lasting brain protection against infarcted lesion development via BDNF gene-dependent mechanism , 2004, Brain Research.
[58] Nico de Jong,et al. Micromanipulation of endothelial cells: ultrasound-microbubble-cell interaction. , 2004, Ultrasound in medicine & biology.
[59] K. Hynynen,et al. Resonance frequency of microbubbles in small blood vessels: a numerical study , 2004, IEEE Ultrasonics Symposium, 2004.
[60] Willem Boogerd,et al. Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours? , 2004, Cancer treatment reviews.
[61] K. Hynynen,et al. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. , 2004, Ultrasound in medicine & biology.
[62] Natalia Vykhodtseva,et al. 500‐element ultrasound phased array system for noninvasive focal surgery of the brain: A preliminary rabbit study with ex vivo human skulls , 2004, Magnetic resonance in medicine.
[63] R. Bukowski,et al. The promise of targeted therapy: cancer drugs become more specific. , 2004, Cleveland Clinic journal of medicine.
[64] W. Pardridge. Intravenous, non-viral RNAi gene therapy of brain cancer , 2004, Expert opinion on biological therapy.
[65] M. Haluska,et al. Osmotic blood-brain barrier modification for the treatment of malignant brain tumors. , 2004, Clinical journal of oncology nursing.
[66] Hongwei Jin,et al. Cortical spreading depression activates and upregulates MMP-9. , 2004, The Journal of clinical investigation.
[67] M. Harris. Monoclonal antibodies as therapeutic agents for cancer. , 2004, The Lancet. Oncology.
[68] Gregory T. Clement,et al. The feasibility of noninvasive image‐guided treatments of brain disorders by focused ultrasound , 2004 .
[69] L. Curiel,et al. Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high-intensity focused ultrasonography. , 2004, Urology.
[70] Cheri X Deng,et al. Ultrasound-induced cell membrane porosity. , 2004, Ultrasound in medicine & biology.
[71] Emil-Alexandru Brujan,et al. The role of cavitation microjets in the therapeutic applications of ultrasound. , 2004, Ultrasound in medicine & biology.
[72] Roy W. Martin,et al. Liver Hemostasis With High‐Intensity Ultrasound , 2004, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.
[73] Wen-zhi Chen,et al. A randomised clinical trial of high-intensity focused ultrasound ablation for the treatment of patients with localised breast cancer , 2003, British Journal of Cancer.
[74] D. Hawkins,et al. Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy , 2003, Cancer.
[75] D. Gianfelice,et al. MR Imaging-guided Focused Ultrasound Surgery of Breast Cancer: Correlation of Dynamic Contrast-enhanced MRI with Histopathologic Findings , 2003, Breast Cancer Research and Treatment.
[76] E. Neuwelt,et al. BR96–DOX Immunoconjugate Targeting of Chemotherapy in Brain Tumor Models , 2003, Journal of Neuro-Oncology.
[77] Volker Sturm,et al. Imaging‐guided convection‐enhanced delivery and gene therapy of glioblastoma , 2003, Annals of neurology.
[78] M Pernot,et al. High power transcranial beam steering for ultrasonic brain therapy. , 2003, Physics in medicine and biology.
[79] R. J. Cersosimo,et al. Monoclonal antibodies in the treatment of cancer, Part 1. , 2003, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
[80] Shahram Vaezy,et al. High-intensity focused US: a potential new treatment for GI bleeding. , 2003, Gastrointestinal endoscopy.
[81] Yi Ai,et al. Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects , 2003, The Journal of comparative neurology.
[82] E. Winer,et al. Central nervous system metastases in women who receive trastuzumab‐based therapy for metastatic breast carcinoma , 2003, Cancer.
[83] E. Lower,et al. Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival. , 2003, Clinical breast cancer.
[84] W. Pardridge. Blood-brain barrier drug targeting: the future of brain drug development. , 2003, Molecular interventions.
[85] Kullervo Hynynen,et al. MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study. , 2003, Radiology.
[86] K. Hynynen,et al. The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison). , 2003, Ultrasound in medicine & biology.
[87] M Tanter,et al. Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans. , 2003, The Journal of the Acoustical Society of America.
[88] W. Pardridge. Neurotrophins, neuroprotection and the blood-brain barrier. , 2002, Current opinion in investigational drugs.
[89] G. Jurkovich,et al. Spleen hemostasis using high-intensity ultrasound: survival and healing. , 2002, The Journal of trauma.
[90] W. Pardridge,et al. Drug and Gene Delivery to the Brain The Vascular Route , 2002, Neuron.
[91] Wen-zhi Chen,et al. [High intensity focused ultrasound in the treatment of primary malignant bone tumor]. , 2002, Zhonghua zhong liu za zhi [Chinese journal of oncology].
[92] Shahram Vaezy,et al. An image-guided high intensity focused ultrasound device for uterine fibroids treatment. , 2002, Medical physics.
[93] R. Bell. What Can We Learn from Herceptin® Trials in Metastatic Breast Cancer? , 2002, Oncology.
[94] K. Possinger,et al. Chemotherapy for Breast Cancer Brain Metastases , 2002, Oncology Research and Treatment.
[95] G. Giaccone,et al. Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: a prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[96] Peter Alken,et al. High intensity focused ultrasound as noninvasive therapy for multilocal renal cell carcinoma: case study and review of the literature. , 2002, The Journal of urology.
[97] Gregory T. Clement,et al. A non-invasive method for focusing ultrasound through the human skull. , 2002, Physics in medicine and biology.
[98] R. Coleman,et al. Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[99] H. Winn,et al. High-intensity focused ultrasound selectively disrupts the blood-brain barrier in vivo. , 2002, Ultrasound in medicine & biology.
[100] W. Pardridge,et al. Drug and gene targeting to the brain with molecular trojan horses , 2002, Nature Reviews Drug Discovery.
[101] Jifeng Feng,et al. A Phase II Study of Etoposide, Doxorubicin, and Carboplatin in the Treatment of Advanced Gastric Cancer , 2002, American journal of clinical oncology.
[102] B. Anderson,et al. A new method for the investigation of capillary structure , 2002, Journal of Neuroscience Methods.
[103] E. Lo,et al. Drug delivery to damaged brain , 2001, Brain Research Reviews.
[104] W. Pardridge. Brain drug targeting and gene technologies. , 2001, Japanese journal of pharmacology.
[105] K. Hynynen,et al. Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. , 2001, Radiology.
[106] J. Ridet,et al. Recombinant proteins for neurodegenerative diseases: the delivery issue , 2001, Trends in Neurosciences.
[107] G. Somjen. Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. , 2001, Physiological reviews.
[108] L. Crum,et al. Therapeutic Ultrasound, Part II * . High Intensity Focused Ultrasound: A Method of Hemostasis , 2001 .
[109] G. Haar,et al. High Intensity Focused Ultrasound for the Treatment of Tumors , 2001, Echocardiography.
[110] J. Kreuter,et al. Nanoparticulate systems for brain delivery of drugs. , 2001, Advanced drug delivery reviews.
[111] Ennis,et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. , 2001, The New England journal of medicine.
[112] W L Nyborg,et al. Biological effects of ultrasound: development of safety guidelines. Part II: general review. , 2001, Ultrasound in medicine & biology.
[113] Ralph A. Nixon,et al. Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease , 2000, Nature.
[114] W L Nyborg,et al. Biological effects of ultrasound: development of safety guidelines. Part I: personal histories. , 2000, Ultrasound in medicine & biology.
[115] F A Jolesz,et al. MRI detection of the thermal effects of focused ultrasound on the brain. , 2000, Ultrasound in medicine & biology.
[116] David Fortin,et al. Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood‐brain barrier for the treatment of patients with malignant brain tumors , 2000, Cancer.
[117] Ajay,et al. Designing libraries with CNS activity. , 1999, Journal of medicinal chemistry.
[118] Jennifer K. Sun,et al. Phased array development for noninvasive focused ultrasound therapy of brain and liver , 1999, Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. N.
[119] J. Kreuter,et al. Significant Transport of Doxorubicin into the Brain with Polysorbate 80-Coated Nanoparticles , 1999, Pharmaceutical Research.
[120] S. Schwarze,et al. In vivo protein transduction: delivery of a biologically active protein into the mouse. , 1999, Science.
[121] J. Borredon,et al. Dynamic In Vivo Measurement of Erythrocyte Velocity and Flow in Capillaries and of Microvessel Diameter in the Rat Brain by Confocal Laser Microscopy , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[122] K Hynynen,et al. Ultrasound technology for hyperthermia. , 1999, Ultrasound in medicine & biology.
[123] Alexander Sasha Rabchevsky,et al. Peripheral injections of Freund's adjuvant in mice provoke leakage of serum proteins through the blood–brain barrier without inducing reactive gliosis , 1999, Brain Research.
[124] M. Singh,et al. Transferrin As A targeting ligand for liposomes and anticancer drugs. , 1999, Current pharmaceutical design.
[125] K Hynynen,et al. The potential of transskull ultrasound therapy and surgery using the maximum available skull surface area. , 1999, The Journal of the Acoustical Society of America.
[126] N. Fisk,et al. Vascular occlusion using focused ultrasound surgery for use in fetal medicine. , 1999, European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology.
[127] A. Stan,et al. Doxorubicin-induced cell death in highly invasive human gliomas. , 1999, Anticancer research.
[128] J. Chapelon,et al. Treatment of localised prostate cancer with transrectal high intensity focused ultrasound. , 1999, European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology.
[129] W. Pardridge,et al. Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems. , 1999, Pharmaceutical science & technology today.
[130] K. Hynynen,et al. Focusing of therapeutic ultrasound through a human skull: a numerical study. , 1998, The Journal of the Acoustical Society of America.
[131] V. Perry,et al. CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood–brain barrier breakdown , 1998, Current Biology.
[132] V. Perry,et al. Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood–brain barrier breakdown in vivo , 1998, Neuroscience.
[133] A. Prosperetti,et al. Physics of acoustic cavitation in liquids: H. G. Flynn’s review 35 years later , 1998 .
[134] Keith L Black,et al. Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomas , 1998, Brain Research.
[135] E. Neuwelt,et al. Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means. , 1998, Neurosurgery.
[136] P. Kornblith. Outwitting the Blood-Brain Barrier for Therapeutic Purposes: Osmotic Opening and Other Means , 1998 .
[137] F A Jolesz,et al. Demonstration of potential noninvasive ultrasound brain therapy through an intact skull. , 1998, Ultrasound in medicine & biology.
[138] K. Chew,et al. HER2/Neu and the Ets transcription activator PEA3 are coordinately upregulated in human breast cancer , 1997, Oncogene.
[139] D. Trombetta,et al. Changes in the permeability of the blood-brain barrier following sodium dodecyl sulphate administration in the rat , 1997, Experimental Brain Research.
[140] A. Lindemann,et al. Chemotherapeutic induction of long-term remission in metastatic medulloblastoma , 1997, Journal of Neuro-Oncology.
[141] J. Huwyler,et al. Brain drug delivery of small molecules using immunoliposomes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[142] J. Katz,et al. Jets from collapsing bubbles , 1996, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.
[143] W. Mark Saltzman,et al. Chemotherapeutic Drugs Released from Polymers: Distribution of 1,3-bis(2-chloroethyl)-l-nitrosourea in the Rat Brain , 1996, Pharmaceutical Research.
[144] T. Leighton,et al. The one-dimensional bubble: an unusual oscillator, with applications to human bioeffects of underwater sound , 1995 .
[145] W. Mark Saltzman,et al. Distribution of nerve growth factor following direct delivery to brain interstitium , 1995, Brain Research.
[146] B. Öztaş,et al. Intracarotid hypothermic saline infusion: a new method for reversible blood-brain barrier disruption in anesthetized rats , 1995, Neuroscience Letters.
[147] P. Mcnaughton,et al. Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[148] W. Pardridge,et al. Transport of Human Recombinant Brain-Derived Neurotrophic Factor (BDNF) Through the Rat Blood−Brain Barrier in Vivo Using Vector-Mediated Peptide Drug Delivery , 1994, Pharmaceutical Research.
[149] M. Radeke,et al. Distribution of Intracerebral Ventricularly Administered Neurotrophins in Rat Brain and Its Correlation with Trk Receptor Expression , 1994, Experimental Neurology.
[150] T. Leighton. The Acoustic Bubble , 1994 .
[151] U. Bickel,et al. Delivery of peptides and proteins through the blood-brain barrier. , 1993, Advanced drug delivery reviews.
[152] P. Riesz,et al. Free radical formation induced by ultrasound and its biological implications. , 1992, Free radical biology & medicine.
[153] W. Pardridge. Advances in cell biology of blood-brain barrier transport. , 1991, Seminars in cell biology.
[154] E. Russell Ritenour,et al. Ultrasound: Its Chemical, Physical, and Biological Effects , 1989 .
[155] K. Suslick. Ultrasound: Its Chemical, Physical, and Biological Effects , 1988 .
[156] D. Miller,et al. A review of the ultrasonic bioeffects of microsonation, gas-body activation, and related cavitation-like phenomena. , 1987, Ultrasound in medicine & biology.
[157] S. Larson,et al. Increased delivery of tumor-specific monoclonal antibodies to brain after osmotic blood-brain barrier modification in patients with melanoma metastatic to the central nervous system. , 1987, Neurosurgery.
[158] Protection,et al. Ultrasound: Medical Applications, Biological Effects, and Hazard Potential , 1987 .
[159] J. Minna,et al. Osmotic blood-brain barrier modification: monoclonal antibody, albumin, and methotrexate delivery to cerebrospinal fluid and brain. , 1985, Neurosurgery.
[160] P. Edmonds,et al. Evidence for free radical production by ultrasonic cavitation in biological media. , 1983, Ultrasound in medicine & biology.
[161] H. G. Flynn. Generation of transient cavities in liquids by microsecond pulses of ultrasound , 1982 .
[162] M. Salcman,et al. Morphologic effect of dimethyl sulfoxide on the blood-brain barrier. , 1982, Science.
[163] R. Apfel. Acoustic cavitation: a possible consequence of biomedical uses of ultrasound. , 1982, The British journal of cancer. Supplement.
[164] L. Gavrilov,et al. [Use of focused ultrasound for local destruction of different brain structures]. , 1976, Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova.
[165] C. Milstein,et al. Continuous cultures of fused cells secreting antibody of predefined specificity , 1975, Nature.
[166] W. T. Coakley,et al. Acoustical Detection of Single Cavitation Events in a Focused Field in Water at 1 MHz , 1971 .
[167] J. Pond,et al. Trackless lesions in nervous tissues produced by high intensity focused ultrasound (high-frequency mechanical waves). , 1968, Journal of anatomy.
[168] Allan D. Pierce,et al. Physical acoustics : principles and methods , 1965 .
[169] P. P. Lele,et al. A simple method for production of trackless focal lesions with focused ultrasound: statistical evaluation of the effects of irradiation on the central nervous system of the cat , 1962, The Journal of physiology.
[170] Belle,et al. An experimental neuropathological study of the effects of high-frequency focused ultrasound on the brain of the cat. , 1961, Journal of neuropathology and experimental neurology.
[171] Milton S. Plesset,et al. Theory of Rectified Diffusion of Mass into Gas Bubbles , 1961 .
[172] E. Bell,et al. Progress and problems in the neurological applications of focused ultrasound. , 1960, Journal of neurosurgery.
[173] L. Bakay,et al. Ultrasonically produced changes in the blood-brain barrier. , 1956, A.M.A. archives of neurology and psychiatry.
[174] W. Fry,et al. Effects of high intensity ultrasound on the central nervous system of the cat , 1955, The Journal of comparative neurology.
[175] A. A. P. Leo,et al. PIAL CIRCULATION AND SPREADING DEPRESSION OF ACTIVITY IN THE CEREBRAL CORTEX , 1944 .
[176] W. Pardridge. The blood-brain barrier: Bottleneck in brain drug development , 2005, NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics.
[177] T. Buchholz,et al. Inflammatory breast cancer: current concepts in local management. , 2005, Breast disease.
[178] J. Voges,et al. Liposome-mediated suicide gene therapy in humans. , 2005, Methods in enzymology.
[179] D. Goldenberg,et al. Perspectives on cancer therapy with radiolabeled monoclonal antibodies. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[180] M. Zalutsky. Current status of therapy of solid tumors: brain tumor therapy. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[181] D. Alberts,et al. Role of pegylated liposomal doxorubicin in ovarian cancer. , 2005, Gynecologic oncology.
[182] W. K. Cullen,et al. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. , 2005, Nature medicine.
[183] K. Naresh,et al. Consolidation radiation after complete remission in Hodgkin's disease following six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy: is there a need? , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[184] Henry Brem,et al. Recent Advances in Brain Tumor Therapy: Local Intracerebral Drug Delivery by Polymers , 2004, Investigational New Drugs.
[185] K. Hynynen,et al. Forced linear oscillations of microbubbles in blood capillaries. , 2004, The Journal of the Acoustical Society of America.
[186] G. Gerhardt,et al. Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases. , 2003, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.
[187] F A Jolesz,et al. Non-invasive opening of BBB by focused ultrasound. , 2003, Acta neurochirurgica. Supplement.
[188] W. Hall,et al. Importance of dose intensity in neuro-oncology clinical trials: summary report of the Sixth Annual Meeting of the Blood-Brain Barrier Disruption Consortium. , 2001, Neuro-oncology.
[189] P. Zhong,et al. Dynamics of bubble oscillation in constrained media and mechanisms of vessel rupture in SWL. , 2001, Ultrasound in medicine & biology.
[190] S. Vaezy,et al. High intensity focused ultrasound: a method of hemostasis. , 2001, Echocardiography.
[191] P. S. St George-Hyslop,et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. , 2000, Nature.
[192] A. Ghose,et al. A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases. , 1999, Journal of combinatorial chemistry.
[193] M. Küçük,et al. Reversible blood-brain barrier dysfunction after intracarotid hyperthermic saline infusion. , 1998, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.
[194] N. Riley. Acoustic Streaming , 1998 .
[195] K Hynynen,et al. Noninvasive arterial occlusion using MRI-guided focused ultrasound. , 1996, Ultrasound in medicine & biology.
[196] Morton W. Miller,et al. A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective. , 1996, Ultrasound in medicine & biology.
[197] W. Saltzman,et al. Stabilization of nerve growth factor in controlled release polymers and in tissue. , 1996, Journal of biomaterials science. Polymer edition.
[198] K Hynynen,et al. Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo. , 1995, Ultrasound in medicine & biology.
[199] R. M. Thomas,et al. Ultrasound contrast agents nucleate inertial cavitation in vitro. , 1995, Ultrasound in medicine & biology.
[200] Timothy G. Leighton,et al. Applications of one-dimensional bubbles to lithotripsy, and to diver response to low frequency sound , 1995 .
[201] P F Morrison,et al. High-flow microinfusion: tissue penetration and pharmacodynamics. , 1994, The American journal of physiology.
[202] E. Kano,et al. Free radical formation induced by ultrasound and its effects on strand breaks in DNA of cultured FM3A cells. , 1993, Free radical research communications.
[203] S. Vallabhajosula,et al. Effect of blood-brain barrier and blood-tumor barrier modification on central nervous system liposomal uptake. , 1993, Cancer investigation.
[204] W. Wilson,et al. Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain. , 1992, Cancer research.
[205] H. Wachtel,et al. Temporally-specific modification of myelinated axon excitability in vitro following a single ultrasound pulse. , 1990, Ultrasound in medicine & biology.
[206] R F Heimburger,et al. Ultrasound and the blood-brain barrier. , 1990, Advances in experimental medicine and biology.
[207] M. Gautherie,et al. Methods of External Hyperthermic Heating , 1990, Clinical Thermology.
[208] K. Hynynen. Biophysics and Technology of Ultrasound Hyperthermia , 1990 .
[209] H. Wachtel,et al. Transient modification of nerve excitability in vitro by single ultrasound pulses. , 1990, Biomedical sciences instrumentation.
[210] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.
[211] Padmakar P. Lele,et al. Effects of Ultrasound on “Solid” Mammalian Tissues and Tumors In Vivo , 1987 .
[212] G. Nussbaum. Physical aspects of hyperthermia , 1982 .
[213] L. Crum. Acoustic Cavitation , 1982 .
[214] W. McGuire,et al. Breast Cancer 4 , 1981, Springer US.
[215] Wesley Le Mars Nyborg,et al. 11 - Acoustic Streaming , 1965 .