PROPELLER MRI visualizezs detailed pathology of hippocampal sclerosis

Purpose:Hippocampal sclerosis (HS) is the most common cause of refractory temporal lobe epilepsy. Histopathologically, HS is characterized by neuron loss and gliosis. HS can be identified on MRI by signal increase on T2‐weighted images and volume loss on T1‐weighted volume images. The Periodically Rotated Overlapping Parallel Lines with Enhanced Reconstruction (“PROPELLER”) sequence has excellent contrast between grey and white matter and compensates for subjects moving during the scan. The aim of the current report was to explore PROPELLER image quality of the hippocampus compared to routine sequences.

[1]  C. Elger,et al.  A new clinico-pathological classification system for mesial temporal sclerosis , 2007, Acta Neuropathologica.

[2]  Val M. Runge,et al.  Brain Magnetic Resonance Imaging at 3 Tesla Using BLADE Compared With Standard Rectilinear Data Sampling , 2006, Investigative radiology.

[3]  Maria Thom,et al.  Reliable Registration of Preoperative MRI with Histopathology after Temporal Lobe Resections , 2005, Epilepsia.

[4]  James G Pipe,et al.  Brain imaging in the unsedated pediatric patient: comparison of periodically rotated overlapping parallel lines with enhanced reconstruction and single-shot fast spin-echo sequences. , 2003, AJNR. American journal of neuroradiology.

[5]  P. Hof,et al.  Cytoarchitecture of the human cerebral cortex: MR microscopy of excised specimens at 9.4 Tesla. , 2002, AJNR. American journal of neuroradiology.

[6]  J G Pipe,et al.  PROPELLER MRI: Clinical testing of a novel technique for quantification and compensation of head motion , 2001, Journal of magnetic resonance imaging : JMRI.

[7]  J. Pipe Motion correction with PROPELLER MRI: Application to head motion and free‐breathing cardiac imaging , 1999, Magnetic resonance in medicine.

[8]  John S. Duncan,et al.  Guidelines for Neuroimaging Evaluation of Patients with Uncontrolled Epilepsy Considered for Surgery , 1998, Epilepsia.

[9]  S. Spencer,et al.  Hippocampal sclerosis , 1995, Neurology.

[10]  A. Connelly,et al.  Optimizing the diagnosis of hippocampal sclerosis using MR imaging. , 1993, AJNR. American journal of neuroradiology.

[11]  C. Houser Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy , 1990, Brain Research.

[12]  G. Jackson,et al.  Hippocampal sclerosis can be reliably detected by magnetic resonance imaging , 1990, Neurology.

[13]  G. Cascino,et al.  Mossy fiber synaptic reorganization in the epileptic human temporal lobe , 1989, Annals of neurology.