Pharmacokinetic and pharmacodynamic investigation of ELND006, a novel APP-selective gamma-secretase inhibitor, on amyloid-β concentrations in the brain, CSF and plasma of multiple nonclinical species following oral administration
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R. Motter | D. Kholodenko | K. Hu | M. Bova | G. Basi | Michael K. Lee | D. Ness | K. Quinn | E. Goldbach | Anna Liao | G. Probst | M. Dappen | Lany Ruslim | E. Brigham | Grace T Kwong | Pamela Santiago | Christopher P. Willits | Xiao-hua Chen | Lan Nguyen | W. Wallace | J. Jagodziński | Susanna S. Hemphill | Huifang Ni | Tovah Eichenbaum | Pearl Tang-Tanaka