Fracture Repair and Bone Grafting

[1]  D. Davy,et al.  The Effects of Processing and Low Dose Irradiation on Cortical Bone Grafts , 2000, Clinical orthopaedics and related research.

[2]  P. Soucacos,et al.  Electric stimulation and hyperbaric oxygen therapy in the treatment of nonunions. , 2006, Injury.

[3]  Diane Hu,et al.  A model for intramembranous ossification during fracture healing , 2002, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[4]  R. Leighton,et al.  A Multicenter , Prospective , Randomized Study Phosphate Cement for Defect Augmentation in Tibial Plateau Comparison of Autogenous Bone Graft and Endothermic Calcium , 2008 .

[5]  V. Rosen,et al.  Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. , 1998, Clinical orthopaedics and related research.

[6]  H. Kronenberg PTHrP and Skeletal Development , 2006, Annals of the New York Academy of Sciences.

[7]  C. Siebert,et al.  A bFGF/TCP-composite inhibits bone formation in a sheep model. , 2008, Journal of biomedical materials research. Part B, Applied biomaterials.

[8]  S. Schneeweiss,et al.  The relation between bisphosphonate use and non-union of fractures of the humerus in older adults , 2009, Osteoporosis International.

[9]  B. W. Schreurs,et al.  Femoral component revision with use of impaction bone-grafting and a cemented polished stem. Surgical technique. , 2006, The Journal of bone and joint surgery. American volume.

[10]  J. Li,et al.  Long‐Term Effect of Incadronate Disodium (YM‐175) on Fracture Healing of Femoral Shaft in Growing Rats , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[11]  U. Ripamonti,et al.  Osteogenic protein‐1, a bone morphogenetic protein, induces angiogenesis in the chick chorioallantoic membrane and synergizes with basic fibroblast growth factor and transforming growth factor‐β1 , 2000, The Anatomical record.

[12]  R. Eliakim,et al.  Nicotine modulates bone metabolism-associated gene expression in osteoblast cells , 2009, Journal of Bone and Mineral Metabolism.

[13]  T. Albert,et al.  A Pilot Study Evaluating the Safety and Efficacy of OP-1 Putty (rhBMP-7) as a Replacement for Iliac Crest Autograft in Posterolateral Lumbar Arthrodesis for Degenerative Spondylolisthesis , 2004, Spine.

[14]  M. Finnegan,et al.  Effect of smoking on tibial shaft fracture healing. , 1999, Clinical orthopaedics and related research.

[15]  M. Bostrom,et al.  Systemic corticosteroids inhibit bone healing in a rabbit ulnar osteotomy model , 2000, Acta orthopaedica Scandinavica.

[16]  Ashok K. Goel,et al.  Percutaneous bone marrow grafting for the treatment of tibial non-union. , 2005, Injury.

[17]  T A Einhorn,et al.  The expression of cytokine activity by fracture callus , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  T. Albert,et al.  Comparison of OP-1 Putty (rhBMP-7) to Iliac Crest Autograft for Posterolateral Lumbar Arthrodesis: A Minimum 2-Year Follow-up Pilot Study , 2005, Spine.

[19]  Hiroshi Fukuda,et al.  Recombinant Human Basic Fibroblast Growth Factor Accelerates Fracture Healing by Enhancing Callus Remodeling in Experimental Dog Tibial Fracture , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[20]  M. Urist Bone: Formation by Autoinduction , 1965, Science.

[21]  B. Alman,et al.  Beta-Catenin Signaling Plays a Disparate Role in Different Phases of Fracture Repair: Implications for Therapy to Improve Bone Healing , 2007, PLoS medicine.

[22]  B. Steele,et al.  Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study , 2009, Osteoporosis International.

[23]  A. Harris,et al.  Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis , 2004, Journal of Cancer Research and Clinical Oncology.

[24]  T. Einhorn,et al.  Impaired Intramembranous Bone Formation during Bone Repair in the Absence of Tumor Necrosis Factor-Alpha Signaling , 2001, Cells Tissues Organs.

[25]  John R. Johnson,et al.  Initial Fusion Rates With Recombinant Human Bone Morphogenetic Protein-2/Compression Resistant Matrix and a Hydroxyapatite and Tricalcium Phosphate/Collagen Carrier in Posterolateral Spinal Fusion , 2005, Spine.

[26]  E. Schwarz,et al.  Teriparatide (1‐34 human PTH) regulation of osterix during fracture repair , 2008, Journal of cellular biochemistry.

[27]  H. Sandhu,et al.  Use of Recombinant Human Bone Morphogenetic Protein-2 in Spinal Fusion Applications , 2002, Spine.

[28]  Chao Wan,et al.  Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[29]  D. Graves,et al.  Impaired Fracture Healing in the Absence of TNF‐α Signaling: The Role of TNF‐α in Endochondral Cartilage Resorption , 2003 .

[30]  K. Birnbaum,et al.  Use of extracorporeal shock-wave therapy (ESWT) in the treatment of non-unions , 2002, Archives of Orthopaedic and Trauma Surgery.

[31]  H. Chambers,et al.  Complications of iliac crest bone graft harvesting. , 1996, Clinical orthopaedics and related research.

[32]  S. Glassman,et al.  Platelet Gel (AGF) Fails to Increase Fusion Rates in Instrumented Posterolateral Fusions , 2005, Spine.

[33]  L. Titus,et al.  1998 Volvo Award Winner in Basic Science Studies: Lumbar Spine Fusion by Local Gene Therapy With a cDNA Encoding a Novel Osteoinductive Protein (LMP‐1) , 1998, Spine.

[34]  R. Buckley,et al.  A prospective randomized controlled trial of a bioresorbable calcium phosphate paste (alpha-BSM) in treatment of displaced intra-articular calcaneal fractures. , 2009, The Journal of trauma.

[35]  R. Delamarter,et al.  Intervariability and Intravariability of Bone Morphogenetic Proteins in Commercially Available Demineralized Bone Matrix Products , 2006, Spine.

[36]  J. Cook,et al.  Enhanced fracture and soft-tissue healing by means of anabolic dietary supplementation. , 2006, The Journal of bone and joint surgery. American volume.

[37]  J. Lane,et al.  Recent Advances Toward the Clinical Application of PTH (1-34) in Fracture Healing , 2009, HSS Journal.

[38]  N. Ebraheim,et al.  Bone‐Graft Harvesting From Iliac and Fibular Donor Sites: Techniques and Complications , 2001, The Journal of the American Academy of Orthopaedic Surgeons.

[39]  A. Mcgregor,et al.  Fracture healing in HIV-positive populations. , 2008, The Journal of bone and joint surgery. British volume.

[40]  I. Hvid,et al.  Recombinant human vascular endothelial growth factor enhances bone healing in an experimental nonunion model. , 2005, The Journal of bone and joint surgery. British volume.

[41]  B. W. Schreurs,et al.  Acetabular reconstruction with impaction bone-grafting and a cemented cup in patients younger than fifty years old: a concise follow-up, at twenty to twenty-eight years, of a previous report. , 2011, The Journal of bone and joint surgery. American volume.

[42]  H. Kreder,et al.  The Effect of Smoking on Clinical Outcome and Complication Rates Following Ilizarov Reconstruction , 2003, Journal of orthopaedic trauma.

[43]  S. T. Yoon,et al.  The effects of doxorubicin (adriamycin) on spinal fusion: an experimental model of posterolateral lumbar spinal arthrodesis. , 2004, The spine journal : official journal of the North American Spine Society.

[44]  M. I. Chen,et al.  1995 Volvo Award in basic sciences. The use of an osteoinductive growth factor for lumbar spinal fusion. Part I: Biology of spinal fusion. , 1995, Spine.

[45]  C. Colnot,et al.  Analyzing the cellular contribution of bone marrow to fracture healing using bone marrow transplantation in mice. , 2006, Biochemical and biophysical research communications.

[46]  M. Urist,et al.  The bone induction principle. , 1967, Clinical orthopaedics and related research.

[47]  S. Boden,et al.  Biologic enhancement of spinal fusion. , 1995, Spine.

[48]  W Lehmann,et al.  The role of angiogenesis in a murine tibial model of distraction osteogenesis. , 2004, Bone.

[49]  G. Zych,et al.  Osteogenic Protein-1 (Bone Morphogenetic Protein-7) in the Treatment of Tibial Nonunions: A Prospective, Randomized Clinical Trial Comparing rhOP-1 with Fresh Bone Autograft* , 2001, The Journal of bone and joint surgery. American volume.

[50]  L. Titus,et al.  Gene expression during autograft lumbar spine fusion and the effect of bone morphogenetic protein 2 , 1998 .

[51]  L. Dorr,et al.  Hydroxyapatite-coated proximal ingrowth femoral stems. A matched pair control study. , 1995, Clinical orthopaedics and related research.

[52]  L. Titus,et al.  The Effect of Nicotine on Gene Expression During Spine Fusion , 2000, Spine.

[53]  S. Takahashi,et al.  A synthetic porous ceramic as a bone graft substitute in the surgical management of scoliosis: a prospective, randomized study. , 2000, Spine.

[54]  M. Bouxsein,et al.  Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy. , 2009, The Journal of hand surgery.

[55]  T. Ducker,et al.  The Use of Freeze-Dried Allograft Bone for Anterior Cervical Fusions , 1991, Spine.

[56]  C. Kelly,et al.  The Use of a Surgical Grade Calcium Sulfate as a Bone Graft Substitute: Results of a Multicenter Trial , 2001, Clinical orthopaedics and related research.

[57]  Z. Werb,et al.  Role of Matrix Metalloproteinase 13 in Both Endochondral and Intramembranous Ossification during Skeletal Regeneration , 2007, PloS one.

[58]  T. Lowe,et al.  A Prospective Analysis of Autograft Versus Allograft in Posterolateral Lumbar Fusion in the Same Patient: A Minimum of 1‐Year Follow‐up in 144 Patients , 1994, Spine.

[59]  J. L. Russell,et al.  Donor age and gender effects on osteoinductivity of demineralized bone matrix. , 2004, Journal of biomedical materials research. Part B, Applied biomaterials.

[60]  G. Drosos,et al.  Safety and efficacy of commercially available demineralised bone matrix preparations: a critical review of clinical studies. , 2007, Injury.

[61]  M. Bolander,et al.  Defects of early fracture-healing in experimental diabetes. , 1989, The Journal of bone and joint surgery. American volume.

[62]  Michael P. Kelly,et al.  Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur. , 2010, The New England journal of medicine.

[63]  R. Baron,et al.  Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[64]  A. Ladd,et al.  Norian SRS cement compared with conventional fixation in distal radial fractures. A randomized study. , 2003, The Journal of bone and joint surgery. American volume.

[65]  Robin Patel,et al.  Levofloxacin and Trovafloxacin Inhibition of Experimental Fracture-Healing , 2003, Clinical orthopaedics and related research.

[66]  P. Giannoudis,et al.  Application of BMP-7 to tibial non-unions: a 3-year multicenter experience. , 2008, Injury.

[67]  H. Redmond,et al.  Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[68]  Michael J Yaszemski,et al.  Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration. , 2009, Biomaterials.

[69]  G. Muschler,et al.  Evaluation of Collagen Ceramic Composite Graft Materials in a Spinal Fusion Model , 1996, Clinical orthopaedics and related research.

[70]  Sheldon S. Lin,et al.  The effects of local platelet rich plasma delivery on diabetic fracture healing. , 2006, Bone.

[71]  Thomas A Einhorn,et al.  Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment. , 2009, Bone.

[72]  Benjamin A Alman,et al.  Wnt pathway, an essential role in bone regeneration , 2009, Journal of cellular biochemistry.

[73]  Timo Jämsä,et al.  Adenoviral VEGF‐A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues , 2003, The journal of gene medicine.

[74]  D. Kallmes,et al.  Percutaneous spinal fusion using bone morphogenetic protein-2 gene therapy. , 1999, Journal of neurosurgery.

[75]  M. Grevitt,et al.  A Prospective Randomized Comparison of Coralline Hydroxyapatite With Autograft in Cervical Interbody Fusion , 2003, Spine.

[76]  G. Stein,et al.  Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: A novel role of the cysteinyl LT‐1 receptor , 2009, Journal of cellular physiology.

[77]  C. Lavy,et al.  Open fractures of the tibia in HIV positive patients: a prospective controlled single-blind study. , 2004, Injury.

[78]  S. Wientroub,et al.  Simple bone cysts treated by percutaneous autologous marrow grafting. A preliminary report. , 1996, The Journal of bone and joint surgery. British volume.

[79]  M. Costa,et al.  The clinical use of platelet-rich plasma in the promotion of bone healing: a systematic review. , 2009, Injury.

[80]  T. Einhorn,et al.  Spatial and temporal gene expression in chondrogenesis during fracture healing and the effects of basic fibroblast growth factor , 2001, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[81]  L. Qin,et al.  Low‐magnitude high‐frequency vibration accelerates callus formation, mineralization, and fracture healing in rats , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[82]  M E Bolander,et al.  Ciprofloxacin Inhibition of Experimental Fracture-Healing* , 2000, The Journal of bone and joint surgery. American volume.

[83]  N. Epstein A Preliminary Study of the Efficacy of Beta Tricalcium Phosphate as a Bone Expander for Instrumented Posterolateral Lumbar Fusions , 2006, Journal of spinal disorders & techniques.

[84]  D. Morgan,et al.  Sterilization of allograft bone: effects of gamma irradiation on allograft biology and biomechanics , 2006, Cell and Tissue Banking.

[85]  W. Hutton,et al.  Nicotine on the Revascularization of Bone Graft: An Experimental Study in Rabbits , 1994, Spine.

[86]  M. Swiontkowski,et al.  Recombinant human bone morphogenetic protein-2 in open tibial fractures. A subgroup analysis of data combined from two prospective randomized studies. , 2006, The Journal of bone and joint surgery. American volume.

[87]  Subburaman Mohan,et al.  Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair. , 2006, Bone.

[88]  Angela A. Wang,et al.  The effects of obesity surgery on bone metabolism: what orthopedic surgeons need to know. , 2009, American journal of orthopedics.

[89]  Jill A. Helms,et al.  Altered fracture repair in the absence of MMP9 , 2003, Development.

[90]  L. Nordsletten,et al.  Parecoxib and Indomethacin Delay Early Fracture Healing: A Study in Rats , 2009, Clinical orthopaedics and related research.

[91]  T A Einhorn,et al.  Growth Factor Regulation of Fracture Repair , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[92]  K. Seibert,et al.  Differential inhibition of fracture healing by non‐selective and cyclooxygenase‐2 selective non‐steroidal anti‐inflammatory drugs , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[93]  E. Schwarz,et al.  Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. , 2002, The Journal of clinical investigation.

[94]  J. Reginster,et al.  Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. , 2001, The New England journal of medicine.

[95]  C. Saltzman,et al.  Ankle fractures in patients with diabetes mellitus. , 2005, The Journal of bone and joint surgery. British volume.

[96]  H. Stills,et al.  Role of Platelet-Rich Plasma in Acceleration of Bone Fracture Healing , 2008, Annals of plastic surgery.

[97]  H. Mankin,et al.  Bone banking. Update on methods and materials. , 1999, The Orthopedic clinics of North America.

[98]  Intertrochanteric fractures of the femur in rheumatoid arthritis patients. , 1993, Clinical orthopaedics and related research.

[99]  F. Geisler,et al.  Two-Year Fusion Rate Equivalency Between Grafton® DBM Gel and Autograft in Posterolateral Spine Fusion: A Prospective Controlled Trial Employing a Side-by-Side Comparison in the Same Patient , 2004, Spine.

[100]  C. Dodd,et al.  Allograft versus autograft bone in scoliosis surgery. , 1988, The Journal of bone and joint surgery. British volume.

[101]  D. Ornitz,et al.  Fibroblast growth factor expression during skeletal fracture healing in mice , 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

[102]  C. H. Herndon,et al.  The fate of autogenous and homogenous bone grafts. , 1955, The Journal of bone and joint surgery. American volume.

[103]  Jay R Lieberman,et al.  Osteoinductivity of commercially available demineralized bone matrix. Preparations in a spine fusion model. , 2004, The Journal of bone and joint surgery. American volume.

[104]  R. Loder,et al.  The influence of diabetes mellitus on the healing of closed fractures. , 1988, Clinical orthopaedics and related research.

[105]  S. Santavirta,et al.  Recombinant Human Bone Morphogenetic Protein-2 for Treatment of Open Tibial Fractures: A Prospective, Controlled, Randomized Study of Four Hundred and Fifty Patients , 2002, The Journal of bone and joint surgery. American volume.

[106]  T. Howe,et al.  An emerging pattern of subtrochanteric stress fractures: a long-term complication of alendronate therapy? , 2008, Injury.

[107]  R. Nusse,et al.  Bone Regeneration Is Regulated by Wnt Signaling , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.