Correction: Purinergic signaling on leukocytes infiltrating the LPS-injured lung

1. Friebe D, Yang T, Schmidt T, Borg N, Steckel B, et al. (2014) Purinergic Signaling on Leukocytes Infiltrating the LPS-Injured Lung. PLoS ONE 9(4): e95382. doi:10.1371/journal.pone.0095382 Figure 5. Gene expression of distinct ectoenzymes, transporters and channels in the T cell subsets isolated from lung tissue under basal conditions and 7real-time PCR. (A) Under basal conditions, T cell subsets expressed various ectoenzymes of ATP and NAD degradation cascade as well as nucleotide and nucleoside transporters and channels. Gene expression was normalized to betaactin and relative expression levels are depicted. (B) In the diseased state, Cd38, Cd39 and Cd73were significantly upregulated on T helper cells and tended to be increased in cytotoxic and regulatory T cells. Ent1 transcripts were significantly increased in T helper cells. Data are mean 6 SD (n = 4 mice per group). Fold changes were calculated by comparing the expression under basal conditions to that in the injured lung 7 d post induction of ALI and statistical significance was then assessed by Mann-Whitney U test. *P,0.05, **P,0.01, ***P,0.0001. ALI = acute lung injury, Art2.b = ADP-ribosyltransferase 2b, ATP = adenosine triphosphate, AU = arbitrary units, Cnt = concentrative nucleoside transporter, Cx = connexin, Ent = equilibrative nucleoside transporter, LPS = lipopolysacch, NAD = nicotinamide adenine dinucleotide, Panx-1 = pannexin-1, SD = standard deviation.

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