Evaluation of the effects of intramyocardial injection of DNA expressing vascular endothelial growth factor (VEGF) in a myocardial infarction model in the rat--angiogenesis and angioma formation.

[1]  J. Isner,et al.  Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. , 1998, Circulation.

[2]  H. Blau,et al.  VEGF gene delivery to muscle: potential role for vasculogenesis in adults. , 1998, Molecular cell.

[3]  M. Feucht,et al.  VEGF induces cardiovascular malformation and embryonic lethality. , 1997, The American journal of pathology.

[4]  B. Lewis,et al.  Angiogenesis by gene therapy: a new horizon for myocardial revascularization? , 1997, Cardiovascular research.

[5]  M. Capogrossi,et al.  Gene therapy with angiogenic factors: a new potential approach to the treatment of ischemic diseases. , 1997, Journal of molecular and cellular cardiology.

[6]  F. Sellke,et al.  Hemodynamic effects of intracoronary VEGF delivery: evidence of tachyphylaxis and NO dependence of response. , 1997, The American journal of physiology.

[7]  M. Capogrossi,et al.  Gene therapy for collateral vessel development. , 1997, Cardiovascular research.

[8]  M. Wassef,et al.  Vascular endothelial growth factor confers a growth advantage in vitro and in vivo to stromal cells cultured from neonatal hemangiomas. , 1997, The American journal of pathology.

[9]  M. Majesky.  A little VEGF goes a long way. Therapeutic angiogenesis by direct injection of vascular endothelial growth factor-encoding plasmid DNA. , 1996, Circulation.

[10]  W. Schaper,et al.  Molecular mechanisms of coronary collateral vessel growth. , 1996, Circulation research.

[11]  L. Kedes,et al.  Transplantation of fetal myocardial tissue into the infarcted myocardium of rat. A potential method for repair of infarcted myocardium? , 1996, Circulation.

[12]  Joan W. Miller,et al.  Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate. , 1996, Ophthalmology.

[13]  L. Kedes,et al.  Adenovirus-mediated gene transfer into infarcted myocardium: feasibility, timing, and location of expression. , 1996, Journal of molecular and cellular cardiology.

[14]  L. Kedes,et al.  Avoidance of immune response prolongs expression of genes delivered to the adult rat myocardium by replication-defective adenovirus. , 1996, Circulation.

[15]  S. Epstein,et al.  Comparative effects of basic fibroblast growth factor and vascular endothelial growth factor on coronary collateral development and the arterial response to injury. , 1996, Circulation.

[16]  Takayuki Asahara,et al.  Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb , 1996, The Lancet.

[17]  F. Sellke,et al.  Enhanced microvascular relaxations to VEGF and bFGF in chronically ischemic porcine myocardium. , 1996, The American journal of physiology.

[18]  K Walsh,et al.  Arterial gene transfer for therapeutic angiogenesis in patients with peripheral artery disease. , 1996, Human gene therapy.

[19]  J. Pearlman,et al.  Vascular endothelial growth factor administration in chronic myocardial ischemia. , 1996, The American journal of physiology.

[20]  L. Kedes,et al.  Ischemic/reperfused myocardium can express recombinant protein following direct DNA or retroviral injection. , 1996, Journal of molecular and cellular cardiology.

[21]  Atsushi Namiki,et al.  Hypoxia Induces Vascular Endothelial Growth Factor in Cultured Human Endothelial Cells (*) , 1995, The Journal of Biological Chemistry.

[22]  Y. Satow,et al.  Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. , 1995, Cancer research.

[23]  C. Little,et al.  Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Jason A. Lowry,et al.  Arterial gene therapy for therapeutic angiogenesis in patients with peripheral artery disease. , 1995, Circulation.

[25]  J. Isner,et al.  Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. , 1995, Circulation.

[26]  J. Isner,et al.  Recovery of disturbed endothelium-dependent flow in the collateral-perfused rabbit ischemic hindlimb after administration of vascular endothelial growth factor. , 1995, Circulation.

[27]  J. Isner,et al.  Site-specific therapeutic angiogenesis after systemic administration of vascular endothelial growth factor. , 1995, Journal of vascular surgery.

[28]  J. Isner,et al.  Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia. , 1994, Circulation.

[29]  S. Epstein,et al.  Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. , 1994, Circulation.

[30]  E. Brogi,et al.  Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. , 1994, The Journal of clinical investigation.

[31]  S. Kaul,et al.  An association between collateral blood flow and myocardial viability in patients with recent myocardial infarction. , 1992, The New England journal of medicine.

[32]  G. Repetto,et al.  Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle. , 1992, Journal of cell science.

[33]  Georg Breier,et al.  Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo , 1992, Nature.

[34]  N. Ferrara,et al.  Molecular and biological properties of the vascular endothelial growth factor family of proteins. , 1992, Endocrine reviews.

[35]  G. Repetto,et al.  Direct gene transfer into nonhuman primate myofibers in vivo. , 1992, Human gene therapy.

[36]  J. Winer,et al.  The vascular endothelial growth factor family of polypeptides , 1991, Journal of cellular biochemistry.

[37]  G. Acsadi,et al.  Conditions affecting direct gene transfer into rodent muscle in vivo. , 1991, BioTechniques.

[38]  S. Epstein,et al.  Effects of acidic fibroblast growth factor on normal and ischemic myocardium. , 1991, Circulation research.

[39]  L. Leinwand,et al.  Hormonal modulation of a gene injected into rat heart in vivo. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[40]  S. Bolling,et al.  Expression of recombinant genes in myocardium in vivo after direct injection of DNA. , 1990, Circulation.

[41]  G. Acsadi,et al.  Direct gene transfer into mouse muscle in vivo. , 1990, Science.

[42]  D. Goeddel,et al.  Vascular endothelial growth factor is a secreted angiogenic mitogen. , 1989, Science.

[43]  R. Hendel,et al.  Results of intracoronary recombinant human vascular endothelial growth factor (rhVEGF) administration trial , 1998 .

[44]  M. L. Kaplan,et al.  Behavior of genes directly injected into the rat heart in vivo. , 1992, Circulation research.

[45]  G. Acsadi,et al.  Direct gene transfer and expression into rat heart in vivo. , 1991, The New biologist.

[46]  D. Marm.  Tumor angiogenesis : the pivotal role of vascular endothelial growth factor , 2022 .