Multiple regulatory roles of the transfer RNA-derived small RNAs in cancers

[1]  Junming Guo,et al.  Clinical Diagnostic Values of Transfer RNA-Derived Fragment tRF-41-YDLBRY73W0K5KKOVD and its Effects on the Growth of Gastric Cancer Cells. , 2023, DNA and cell biology.

[2]  A. Dutta,et al.  Function and Therapeutic Implications of tRNA Derived Small RNAs , 2022, Frontiers in Molecular Biosciences.

[3]  Xi Chen,et al.  Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis , 2022, Frontiers of Medicine.

[4]  Wei Peng,et al.  Plasma tRNA-derived small RNAs signature as a predictive and prognostic biomarker in lung adenocarcinoma , 2022, Cancer cell international.

[5]  S.-C. Jim Yeung,et al.  A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study , 2022, Molecular Cancer.

[6]  Weidong Zhao,et al.  tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A) , 2022, Bioengineered.

[7]  Hui Chen,et al.  Identifying Differentially Expressed tRNA-Derived Small Fragments as a Biomarker for the Progression and Metastasis of Colorectal Cancer , 2022, Disease markers.

[8]  Jin Gao,et al.  A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting TRPA1 , 2022, Molecular therapy. Nucleic acids.

[9]  Xi Chen,et al.  Research progress on the tsRNA classification, function, and application in gynecological malignant tumors , 2021, Cell death discovery.

[10]  Y. Shao,et al.  The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway , 2021, Stem cell research & therapy.

[11]  Y. Shao,et al.  The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway , 2021, Stem cell research & therapeutics.

[12]  Xiuling Zhi,et al.  tRNA-derived fragment tRF Lys-CTT-010 promotes triple-negative breast cancer progression by regulating glucose metabolism via G6PC. , 2021, Carcinogenesis.

[13]  Junchao Shi,et al.  Origins and evolving functionalities of tRNA-derived small RNAs. , 2021, Trends in biochemical sciences.

[14]  Yong Peng,et al.  Transfer RNA-derived small RNA: a Rising Star in Oncology. , 2021, Seminars in cancer biology.

[15]  Feng Yan,et al.  tRNA-Derived Fragment tRF-17-79MP9PP Attenuates Cell Invasion and Migration via THBS1/TGF-β1/Smad3 Axis in Breast Cancer , 2021, Frontiers in Oncology.

[16]  Feng Chen,et al.  5′-tRF-GlyGCC: a tRNA-derived small RNA as a novel biomarker for colorectal cancer diagnosis , 2021, Genome Medicine.

[17]  Junming Guo,et al.  Global profile of tRNA-derived small RNAs in gastric cancer patient plasma and identification of tRF-33-P4R8YP9LON4VDP as a new tumor suppressor , 2021, International journal of medical sciences.

[18]  Zhibin Wang,et al.  tsRNAs: Novel small molecules from cell function and regulatory mechanism to therapeutic targets , 2021, Cell proliferation.

[19]  Xu Han,et al.  Circulating tRNA-derived small RNAs (tsRNAs) signature for the diagnosis and prognosis of breast cancer , 2021, NPJ breast cancer.

[20]  D. Weissman,et al.  Nanomaterial Delivery Systems for mRNA Vaccines , 2021, Vaccines.

[21]  G. Song,et al.  tRNALys-Derived Fragment Alleviates Cisplatin-Induced Apoptosis in Prostate Cancer Cells , 2021, Pharmaceutics.

[22]  M. Gullerová,et al.  Dicer Dependent tRNA-Derived Small RNAs Promote Nascent RNA Silencing , 2020 .

[23]  Qian Xu,et al.  The role of Transfer RNA-Derived Small RNAs (tsRNAs) in Digestive System Tumors , 2020, Journal of Cancer.

[24]  Xiaoyuan Xu,et al.  Small RNA sequencing reveals a novel tsRNA‐06018 playing an important role during adipogenic differentiation of hMSCs , 2020, Journal of cellular and molecular medicine.

[25]  M. Kay,et al.  Transfer RNA-Derived Small RNAs: Another Layer of Gene Regulation and Novel Targets for Disease Therapeutics. , 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

[26]  D. Qu,et al.  Lactate Induces Production of the tRNAHis Half to Promote B-lymphoblastic Cell Proliferation. , 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

[27]  Minmin Shi,et al.  Serum tRNA-derived small RNAs as potential novel diagnostic biomarkers for pancreatic ductal adenocarcinoma. , 2020, American journal of cancer research.

[28]  Anindya Dutta,et al.  Noncanonical Roles of tRNAs: tRNA Fragments and Beyond. , 2020, Annual review of genetics.

[29]  M. Manoharan,et al.  Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates , 2020, Nucleic acids research.

[30]  T. Gingeras,et al.  Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment , 2020, Nucleic acids research.

[31]  Manuel A. S. Santos,et al.  Emerging Roles of tRNAs in RNA Virus Infections. , 2020, Trends in biochemical sciences.

[32]  P. Ivanov,et al.  eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function , 2020, Nucleic acids research.

[33]  M. Zheng,et al.  Epigenetic modulations of noncoding RNA: a novel dimension of Cancer biology , 2020, Molecular Cancer.

[34]  J. Prehn,et al.  Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration , 2020, Acta Pharmacologica Sinica.

[35]  Yue Huang,et al.  Serum tRNA‐derived fragments (tRFs) as potential candidates for diagnosis of nontriple negative breast cancer , 2020, Journal of cellular physiology.

[36]  Zhongliang Ma,et al.  Biochemical properties and progress in cancers of tRNA‐derived fragments , 2019, Journal of cellular biochemistry.

[37]  B. Schroen,et al.  tRNAs and tRNA fragments as modulators of cardiac and skeletal muscle function. , 2020, Biochimica et biophysica acta. Molecular cell research.

[38]  T. Abe,et al.  The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation , 2020, bioRxiv.

[39]  Jun Yu,et al.  tiRNAs: A novel class of small noncoding RNAs that helps cells respond to stressors and plays roles in cancer progression , 2020, Journal of cellular physiology.

[40]  G. Stein,et al.  Identification of tRNA‐derived small RNA (tsRNA) responsive to the tumor suppressor, RUNX1, in breast cancer , 2020, Journal of cellular physiology.

[41]  C. Shields,et al.  IsomiRs and tRNA‐derived fragments are associated with metastasis and patient survival in uveal melanoma , 2020, Pigment cell & melanoma research.

[42]  A. Scorilas,et al.  Identification of a novel, internal tRNA-derived RNA fragment as a new prognostic and screening biomarker in chronic lymphocytic leukemia, using an innovative quantitative real-time PCR assay. , 2019, Leukemia research.

[43]  M. Kay,et al.  A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice. , 2019, Cell reports.

[44]  A. Grigoriev,et al.  Inferring targeting modes of Argonaute-loaded tRNA fragments , 2019, RNA biology.

[45]  Anindya Dutta,et al.  Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing , 2019, The Journal of Biological Chemistry.

[46]  P. Ivanov,et al.  Stress granules and neurodegeneration , 2019, Nature Reviews Neuroscience.

[47]  A. Amici,et al.  A novel 3'‐tRNAGlu‐derived fragment acts as a tumor suppressor in breast cancer by targeting nucleolin , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[48]  T. Chiba,et al.  Post-transcriptional regulation of inflammation by RNA binding proteins via cis-elements of mRNAs. , 2019, Journal of biochemistry.

[49]  Seung-Hoon Lee,et al.  Regulation of La/SSB-dependent viral gene expression by pre-tRNA 3′ trailer-derived tRNA fragments , 2019, Nucleic acids research.

[50]  J. Coller,et al.  tRNA Metabolism and Neurodevelopmental Disorders. , 2019, Annual review of genomics and human genetics.

[51]  B. Li,et al.  A tRNA fragment, 5'-tiRNAVal, suppresses the Wnt/β-catenin signaling pathway by targeting FZD3 in breast cancer. , 2019, Cancer letters.

[52]  Nathan S. Abell,et al.  BCDIN3D regulates tRNAHis 3’ fragment processing , 2019, PLoS genetics.

[53]  Junming Guo,et al.  tRNA-derived fragments and tRNA halves: The new players in cancers. , 2019, Cancer letters.

[54]  X. Qiu,et al.  Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis , 2019, Cell Research.

[55]  O. Reina,et al.  Differential expression of human tRNA genes drives the abundance of tRNA-derived fragments , 2019, Proceedings of the National Academy of Sciences.

[56]  Dan Sun,et al.  Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis , 2019, Molecular Cancer.

[57]  L. Laurent,et al.  Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation , 2019, Cell.

[58]  C. Blanpain,et al.  EMT Transition States during Tumor Progression and Metastasis. , 2019, Trends in cell biology.

[59]  N. Polacek,et al.  A tRNA half modulates translation as stress response in Trypanosoma brucei , 2019, Nature Communications.

[60]  Zhike Lu,et al.  Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs , 2018, Nucleic acids research.

[61]  K. Ansel,et al.  Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation , 2018, Cell reports.

[62]  V. Cognat,et al.  Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis , 2018, Nucleic acids research.

[63]  G. Kristiansen,et al.  tRNA-halves are prognostic biomarkers for patients with prostate cancer. , 2018, Urologic oncology.

[64]  Yue Huang,et al.  Hypoxia‐induced tRNA‐derived fragments, novel regulatory factor for doxorubicin resistance in triple‐negative breast cancer , 2018, Journal of cellular physiology.

[65]  Yongmei Yin,et al.  Identification of tRNA‐derived small noncoding RNAs as potential biomarkers for prediction of recurrence in triple‐negative breast cancer , 2018, Cancer medicine.

[66]  P. Marchetti,et al.  Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes , 2018, Nucleic acids research.

[67]  Fan Yang,et al.  tRNA-Derived Fragments as Novel Predictive Biomarkers for Trastuzumab-Resistant Breast Cancer , 2018, Cellular Physiology and Biochemistry.

[68]  P. Ivanov,et al.  The role of RNA modifications in the regulation of tRNA cleavage , 2018, FEBS letters.

[69]  Michael H. Schwartz,et al.  Queuosine modification protects cognate tRNAs against ribonuclease cleavage , 2018, RNA.

[70]  X. Xiao,et al.  Characterization of Human Salivary Extracellular RNA by Next-generation Sequencing. , 2018, Clinical chemistry.

[71]  P. Celichowski,et al.  Transfer RNA-derived fragments target and regulate ribosome-associated aminoacyl-transfer RNA synthetases. , 2018, Biochimica et biophysica acta. Gene regulatory mechanisms.

[72]  A. Ramos,et al.  Joining the dots – protein‐RNA interactions mediating local mRNA translation in neurons , 2018, FEBS letters.

[73]  Anindya Dutta,et al.  tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner , 2018, RNA.

[74]  Jenny Hansson,et al.  Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells , 2018, Cell.

[75]  J. Sheng,et al.  tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA , 2018, Genes.

[76]  X. Xue,et al.  Advances in the delivery of antisense oligonucleotides for combating bacterial infectious diseases. , 2018, Nanomedicine : nanotechnology, biology, and medicine.

[77]  T. Kang,et al.  Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control , 2018, Nature Communications.

[78]  Jian Lu,et al.  Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response , 2018, Nucleic acids research.

[79]  R. Maraia Faculty of 1000 evaluation for A transfer-RNA-derived small RNA regulates ribosome biogenesis. , 2018 .

[80]  Tae-Houn Kim,et al.  Fine-Tuning of Gene Expression by tRNA-Derived Fragments during Abiotic Stress Signal Transduction , 2018, International journal of molecular sciences.

[81]  Xiaodong Zhang,et al.  The emerging role of exosome-derived non-coding RNAs in cancer biology. , 2018, Cancer letters.

[82]  Germán Martínez,et al.  tRNA-derived small RNAs: New players in genome protection against retrotransposons , 2018, RNA biology.

[83]  T. Patel,et al.  Large Differences in Small RNA Composition Between Human Biofluids , 2018, bioRxiv.

[84]  D. Corey,et al.  Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs , 2017, Nucleic acids research.

[85]  F. Slack,et al.  Non-coding RNA networks in cancer , 2017, Nature Reviews Cancer.

[86]  J. Donovan,et al.  Rapid RNase L–driven arrest of protein synthesis in the dsRNA response without degradation of translation machinery , 2017, RNA.

[87]  Yang Wang,et al.  Coding and noncoding landscape of extracellular RNA released by human glioma stem cells , 2017, Nature Communications.

[88]  P. Ivanov,et al.  Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs , 2017, Nature Communications.

[89]  M. Spillman,et al.  A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells , 2017, Oncotarget.

[90]  A. E. Vidal,et al.  Insights into the role of endonuclease V in RNA metabolism in Trypanosoma brucei , 2017, Scientific Reports.

[91]  J. Koh,et al.  Dynamic expression of tRNA‐derived small RNAs define cellular states , 2017, bioRxiv.

[92]  Yong Sun Lee,et al.  Identification of two novel functional tRNA-derived fragments induced in response to respiratory syncytial virus infection. , 2017, The Journal of general virology.

[93]  R. Martienssen,et al.  LTR-Retrotransposon Control by tRNA-Derived Small RNAs , 2017, Cell.

[94]  Phillipe Loher,et al.  The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells , 2017, Nucleic acids research.

[95]  Zesong Li,et al.  tRF/miR-1280 Suppresses Stem Cell-like Cells and Metastasis in Colorectal Cancer. , 2017, Cancer research.

[96]  ping wang,et al.  tRF‐Leu‐CAG promotes cell proliferation and cell cycle in non‐small cell lung cancer , 2017, Chemical biology & drug design.

[97]  S. Dowdy Overcoming cellular barriers for RNA therapeutics , 2017, Nature Biotechnology.

[98]  C. Tisné,et al.  m1A Post-Transcriptional Modification in tRNAs , 2017, Biomolecules.

[99]  Gyorgy Hutvagner,et al.  tRNA-Derived RNA Fragments Associate with Human Multisynthetase Complex (MSC) and Modulate Ribosomal Protein Translation. , 2017, Journal of proteome research.

[100]  Tsutomu Suzuki,et al.  Human BCDIN3D monomethylates cytoplasmic histidine transfer RNA , 2017, Nucleic acids research.

[101]  Ming-Bo Wang,et al.  The tRNA-Derived Small RNAs Regulate Gene Expression through Triggering Sequence-Specific Degradation of Target Transcripts in the Oomycete Pathogen Phytophthora sojae , 2016, Front. Plant Sci..

[102]  Leander Wyss,et al.  A tRNA-derived fragment competes with mRNA for ribosome binding and regulates translation during stress , 2016, RNA biology.

[103]  S. Perner,et al.  Identification of aberrant tRNA-halves expression patterns in clear cell renal cell carcinoma , 2016, Scientific Reports.

[104]  P. Ivanov,et al.  Mechanistic insights into mammalian stress granule dynamics , 2016, The Journal of cell biology.

[105]  R. Keith Slotkin,et al.  tRNA-derived small RNAs target transposable element transcripts , 2016, bioRxiv.

[106]  Canan Kuscu,et al.  Biogenesis and Function of Transfer RNA-Related Fragments (tRFs). , 2016, Trends in biochemical sciences.

[107]  P. Ivanov,et al.  YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression , 2016, Nucleic acids research.

[108]  Giovanni Nigita,et al.  Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer , 2016, Proceedings of the National Academy of Sciences.

[109]  D. Trisciuoglio,et al.  Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies , 2016, Aging.

[110]  Xudong Zhang,et al.  Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder , 2016, Science.

[111]  Xin He,et al.  IL-4 Inhibits the Biogenesis of an Epigenetically Suppressive PIWI-Interacting RNA To Upregulate CD1a Molecules on Monocytes/Dendritic Cells , 2016, The Journal of Immunology.

[112]  Patricia P. Chan,et al.  GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes , 2015, Nucleic Acids Res..

[113]  Xiaoyong Bao,et al.  Respiratory Syncytial Virus Utilizes a tRNA Fragment to Suppress Antiviral Responses Through a Novel Targeting Mechanism. , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

[114]  Phillipe Loher,et al.  Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers , 2015, Proceedings of the National Academy of Sciences.

[115]  Lisa Fish,et al.  Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement , 2015, Cell.

[116]  Z. Ignatova,et al.  Emerging roles of tRNA in adaptive translation, signalling dynamics and disease , 2014, Nature Reviews Genetics.

[117]  S. Whisson,et al.  Fragmentation of tRNA in Phytophthora infestans asexual life cycle stages and during host plant infection , 2014, BMC Microbiology.

[118]  Pavel Ivanov,et al.  tRNA fragments in human health and disease , 2014, FEBS letters.

[119]  J. Lieberman,et al.  G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments , 2014, Proceedings of the National Academy of Sciences.

[120]  Pankaj Kumar,et al.  tRFdb: a database for transfer RNA fragments , 2014, Nucleic Acids Res..

[121]  Suresh B. Mudunuri,et al.  Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets , 2014, BMC Biology.

[122]  Jernej Ule,et al.  Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders , 2014, The EMBO journal.

[123]  Thurston H. Y. Dang,et al.  The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells , 2014, Nucleic acids research.

[124]  Shuxia Liu,et al.  The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells. , 2014, American journal of physiology. Cell physiology.

[125]  J. Lupski,et al.  Human CLP1 Mutations Alter tRNA Biogenesis, Affecting Both Peripheral and Central Nervous System Function , 2014, Cell.

[126]  Tao Pan,et al.  Angiogenin-Cleaved tRNA Halves Interact with Cytochrome c, Protecting Cells from Apoptosis during Osmotic Stress , 2014, Molecular and Cellular Biology.

[127]  A. Corradin,et al.  Small Noncoding RNAs in Cells Transformed by Human T-Cell Leukemia Virus Type 1: a Role for a tRNA Fragment as a Primer for Reverse Transcriptase , 2014, Journal of Virology.

[128]  Yongjun Chu,et al.  RNAi Factors are Present and Active in Human Cell Nuclei , 2014, Cell reports.

[129]  G. Hu,et al.  Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin to control growth and survival , 2013, Journal of Cell Science.

[130]  M. Schaefer,et al.  The RNA methyltransferase Dnmt2 is required for efficient Dicer-2-dependent siRNA pathway activity in Drosophila. , 2013, Cell reports.

[131]  Jernej Ule,et al.  NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs , 2013, Cell reports.

[132]  David I. K. Martin,et al.  5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction , 2013, BMC Genomics.

[133]  Michael Snyder,et al.  A major epigenetic programming mechanism guided by piRNAs. , 2013, Developmental cell.

[134]  Markus Glatzel,et al.  CLP1 links tRNA metabolism to progressive motor-neuron loss , 2013, Nature.

[135]  Graça Raposo,et al.  Extracellular vesicles: Exosomes, microvesicles, and friends , 2013, The Journal of cell biology.

[136]  Georgi K Marinov,et al.  Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. , 2013, Genes & development.

[137]  Andrea Califano,et al.  tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma , 2013, Proceedings of the National Academy of Sciences.

[138]  T. Speed,et al.  A Tetrahymena Piwi bound to mature tRNA 3' fragments activates the exonuclease Xrn2 for RNA processing in the nucleus. , 2012, Molecular cell.

[139]  Wei Li,et al.  A novel class of tRNA-derived small RNAs extremely enriched in mature mouse sperm , 2012, Cell Research.

[140]  F. Tuorto,et al.  RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis , 2012, Nature Structural &Molecular Biology.

[141]  G. Hu,et al.  Emerging role of angiogenin in stress response and cell survival under adverse conditions , 2012, Journal of cellular physiology.

[142]  Norman E. Davey,et al.  Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins , 2012, Cell.

[143]  Y. Sasaguri,et al.  Strong YB‐1 expression is associated with liver metastasis progression and predicts shorter disease‐free survival in advanced gastric cancer , 2012, Journal of surgical oncology.

[144]  Yuan Chang,et al.  Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs , 2012, Nucleic acids research.

[145]  A. Krainer,et al.  RNA therapeutics: beyond RNA interference and antisense oligonucleotides , 2012, Nature Reviews Drug Discovery.

[146]  K. Collins,et al.  Several RNase T2 enzymes function in induced tRNA and rRNA turnover in the ciliate Tetrahymena , 2012, Molecular biology of the cell.

[147]  Steven P Gygi,et al.  Angiogenin-induced tRNA fragments inhibit translation initiation. , 2011, Molecular cell.

[148]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[149]  Yoshihide Hayashizaki,et al.  Deep-sequencing of human Argonaute-associated small RNAs provides insight into miRNA sorting and reveals Argonaute association with RNA fragments of diverse origin , 2011, RNA biology.

[150]  R. Sachidanandam,et al.  A growth-essential Tetrahymena Piwi protein carries tRNA fragment cargo. , 2010, Genes & development.

[151]  Francesca Tuorto,et al.  RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. , 2010, Genes & development.

[152]  Hui Zhou,et al.  Deep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3′ Trailers , 2010, PloS one.

[153]  D. Haussecker,et al.  Human tRNA-derived small RNAs in the global regulation of RNA silencing. , 2010, RNA.

[154]  J. Yong,et al.  tRNA binds to cytochrome c and inhibits caspase activation. , 2010, Molecular cell.

[155]  A. Hopper,et al.  Cellular dynamics of tRNAs and their genes , 2010, FEBS letters.

[156]  G. Barton,et al.  Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs. , 2009, RNA.

[157]  A. Malhotra,et al.  A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). , 2009, Genes & development.

[158]  Wen-Hsiung Li,et al.  Uncovering Small RNA-Mediated Responses to Phosphate Deficiency in Arabidopsis by Deep Sequencing1[W][OA] , 2009, Plant Physiology.

[159]  P. Silver,et al.  Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. , 2009, RNA.

[160]  S. Le,et al.  Pyrosequencing of small non-coding RNAs in HIV-1 infected cells: evidence for the processing of a viral-cellular double-stranded RNA hybrid , 2009, Nucleic acids research.

[161]  R. Sachidanandam,et al.  Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. , 2009, Genes & development.

[162]  Masayuki Nashimoto,et al.  Modulation of Gene Expression by Human Cytosolic tRNase ZL through 5′-Half-tRNA , 2009, PloS one.

[163]  R. Parker,et al.  The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress in Saccharomyces cerevisiae , 2009, The Journal of cell biology.

[164]  S. Yamasaki,et al.  Angiogenin cleaves tRNA and promotes stress-induced translational repression , 2009, The Journal of cell biology.

[165]  E. Wahle,et al.  Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. , 2008, RNA.

[166]  Pamela J Green,et al.  tRNA cleavage is a conserved response to oxidative stress in eukaryotes. , 2008, RNA.

[167]  J. Ladenson,et al.  The role of human ribosomal proteins in the maturation of rRNA and ribosome production. , 2008, RNA.

[168]  Kai-Wei Chang,et al.  RNA-binding proteins in human genetic disease. , 2008, Trends in genetics : TIG.

[169]  A. Hopper,et al.  A decade of surprises for tRNA nuclear-cytoplasmic dynamics. , 2008, Trends in cell biology.

[170]  P. Anderson,et al.  Stress granules: the Tao of RNA triage. , 2008, Trends in biochemical sciences.

[171]  Javier Martinez,et al.  The human RNA kinase hClp1 is active on 3′ transfer RNA exons and short interfering RNAs , 2007, Nature.

[172]  T. Tsuzuki,et al.  YB-1 Is Important for an Early Stage Embryonic Development , 2006, Journal of Biological Chemistry.

[173]  B. Bay,et al.  Significance of the Y-box proteins in human cancers , 2005, Journal of molecular and genetic medicine : an international journal of biomedical research.

[174]  R. Spriggs,et al.  Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry. , 2005, Genes & development.

[175]  M. V. van Eden,et al.  BCL-2 Translation Is Mediated via Internal Ribosome Entry during Cell Stress* , 2004, Journal of Biological Chemistry.

[176]  S. Peltz,et al.  Identification of a Human Endonuclease Complex Reveals a Link between tRNA Splicing and Pre-mRNA 3′ End Formation , 2004, Cell.

[177]  Sonia Cerquozzi,et al.  Translational Induction of the Inhibitor of Apoptosis Protein HIAP2 during Endoplasmic Reticulum Stress Attenuates Cell Death and Is Mediated via an Inducible Internal Ribosome Entry Site Element* , 2004, Journal of Biological Chemistry.

[178]  Saumitra Das,et al.  Hepatitis C Virus Internal Ribosome Entry Site-mediated Translation Is Stimulated by Specific Interaction of Independent Regions of Human La Autoantigen* , 2003, The Journal of Biological Chemistry.

[179]  P. Anderson,et al.  Stress granules: sites of mRNA triage that regulate mRNA stability and translatability. , 2002, Biochemical Society transactions.

[180]  P. Anderson,et al.  Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation , 2002, Cell stress & chaperones.

[181]  G. Packham,et al.  The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock , 2001, Oncogene.

[182]  S. Hasnain,et al.  Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B. , 2000, Biochemistry.

[183]  S. Rybak,et al.  Angiogenin is a cytotoxic, tRNA-specific ribonuclease in the RNase A superfamily. , 1992, The Journal of biological chemistry.

[184]  Alexander Rich,et al.  Three-Dimensional Structure of Yeast Phenylalanine Transfer RNA: Folding of the Polynucleotide Chain , 1973, Science.

[185]  Jian Wang,et al.  TRF-20-M0NK5Y93 suppresses the metastasis of colon cancer cells by impairing the epithelial-to-mesenchymal transition through targeting Claudin-1. , 2021, American journal of translational research.

[186]  B. Xiao,et al.  Using tRNA halves as novel biomarkers for the diagnosis of gastric cancer. , 2019, Cancer biomarkers : section A of Disease markers.

[187]  P. Marchetti,et al.  Pancreatic (cid:2) -cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes , 2018 .

[188]  Y. Pekarsky,et al.  Role of the tRNA-Derived Small RNAs in Cancer: New Potential Biomarkers and Target for Therapy. , 2017, Advances in cancer research.

[189]  Renato Vicentini,et al.  Genome-wide identification and characterization of tRNA-derived RNA fragments in land plants , 2016, Plant Molecular Biology.

[190]  T. Visakorpi,et al.  A comprehensive repertoire of tRNA-derived fragments in prostate cancer , 2016 .

[191]  N. Sonenberg,et al.  Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms. , 2005, Genes & development.

[192]  Junchao Shi,et al.  Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection , 2022 .