A computerized clinical decision support system as a means of implementing depression guidelines.

The authors describe the history and current use of computerized systems for implementing treatment guidelines in general medicine as well as the development, testing, and early use of a computerized decision support system for depression treatment among "real-world" clinical settings in Texas. In 1999 health care experts from Europe and the United States met to confront the well-documented challenges of implementing treatment guidelines and to identify strategies for improvement. They suggested the integration of guidelines into computer systems that is incorporated into clinical workflow. Several studies have demonstrated improvements in physicians' adherence to guidelines when such guidelines are provided in a computerized format. Although computerized decision support systems are being used in many areas of medicine and have demonstrated improved patient outcomes, their use in psychiatric illness is limited. The authors designed and developed a computerized decision support system for the treatment of major depressive disorder by using evidence-based guidelines, transferring the knowledge gained from the Texas Medication Algorithm Project (TMAP). This computerized decision support system (CompTMAP) provides support in diagnosis, treatment, follow-up, and preventive care and can be incorporated into the clinical setting. CompTMAP has gone through extensive testing to ensure accuracy and reliability. Physician surveys have indicated a positive response to CompTMAP, although the sample was insufficient for statistical testing. CompTMAP is part of a new era of comprehensive computerized decision support systems that take advantage of advances in automation and provide more complete clinical support to physicians in clinical practice.

[1]  Jonathan M. Teich,et al.  The impact of computerized physician order entry on medication error prevention. , 1999, Journal of the American Medical Informatics Association : JAMIA.

[2]  J Jespersen,et al.  Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. , 1998, Lancet.

[3]  P. Gross Implementing evidence-based recommendations for health care: a roundtable comparing European and American experiences. , 2000, The Joint Commission journal on quality improvement.

[4]  David Classen,et al.  Implementing Antibiotic Practice Guidelines through Computer-Assisted Decision Support: Clinical and Financial Outcomes , 1996, Annals of Internal Medicine.

[5]  Nick Freemantle,et al.  Computer support for determining drug dose: systematic review and meta-analysis , 1999, BMJ.

[6]  Patrice Degoulet,et al.  Computer-Adjusted Dosage of Anticoagulant Therapy Improves the Quality of Anticoagulation , 1998, MedInfo.

[7]  Fitzmaurice,et al.  Review of computerized decision support systems for oral anticoagulation management , 1998, British journal of haematology.

[8]  Alexander L. Miller,et al.  Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project. , 2004, Archives of general psychiatry.

[9]  R. Raschke,et al.  A computer alert system to prevent injury from adverse drug events: development and evaluation in a community teaching hospital. , 1998, JAMA.

[10]  A. Rush,et al.  Clinical and economic impact of newer versus older antipsychotic medications in a community mental health center. , 1999, Clinical therapeutics.

[11]  KAVEH G. SHOJANIA,et al.  Research Paper: Reducing Vancomycin Use Utilizing a Computer Guideline: Results of a Randomized Controlled Trial , 1998, J. Am. Medical Informatics Assoc..

[12]  R S Evans,et al.  Computerized surveillance of adverse drug events in hospital patients* , 1991, Quality and Safety in Health Care.

[13]  C. Chambers,et al.  Microcomputer-generated reminders. Improving the compliance of primary care physicians with mammography screening guidelines. , 1989, The Journal of family practice.

[14]  Frank Sullivan,et al.  Has general practitioner computing made a difference to patient care? A systematic review of published reports , 1995, BMJ.

[15]  D. Casey,et al.  The relationship of pharmacology to side effects. , 1997, The Journal of clinical psychiatry.

[16]  Henry J. Lowe,et al.  The electronic medical record. A randomized trial of its impact on primary care physicians' initial management of major depression [corrected]. , 2001, Archives of internal medicine.

[17]  J. Marc Overhage,et al.  Case Report: Computerizing Guidelines to Improve Care and Patient Outcomes: The Example of Heart Failure , 1995, J. Am. Medical Informatics Assoc..

[18]  J. Avorn,et al.  Use of computer-based medicaid drug data to analyze and correct inappropriate medication use , 1982, Journal of Medical Systems.

[19]  L. Kohn,et al.  To Err Is Human : Building a Safer Health System , 2007 .

[20]  M H Trivedi,et al.  Development and Implementation of Computerized Clinical Guidelines: Barriers and Solutions , 2002, Methods of Information in Medicine.

[21]  D. Classen,et al.  Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality. , 1997, JAMA.

[22]  T. Clemmer,et al.  A computer-assisted management program for antibiotics and other antiinfective agents. , 1998, The New England journal of medicine.

[23]  R Linnarsson,et al.  Decision support for drug prescription integrated with computer-based patient records in primary care. , 1993, Medical informatics = Medecine et informatique.

[24]  J. Eisenberg,et al.  Changing physicians' practices. , 1993, Tobacco control.

[25]  M. Leaning,et al.  Comparison of oral anticoagulant control by a nurse-practitioner using a computer decision-support system with that by clinicians. , 1997, Clinical and laboratory haematology.

[26]  Anderson Jd,et al.  Increasing the acceptance of clinical information systems. , 1999 .

[27]  C J McDonald,et al.  Delayed Feedback of Physician Performance Versus Immediate Reminders to Perform Preventive Care: Effects on Physician Compliance , 1986, Medical care.

[28]  C. McDonald,et al.  Physician inpatient order writing on microcomputer workstations. Effects on resource utilization. , 1993, JAMA.

[29]  M. Ebell,et al.  Hand-held computers for family physicians. , 1995, The Journal of family practice.

[30]  D. Bates,et al.  Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. , 1998, JAMA.

[31]  T G Tape,et al.  Computerized medical records and preventive health care: success depends on many factors. , 1993, The American journal of medicine.

[32]  R. Haynes,et al.  Effects of Computer-Based Clinical Decision Support Systems on Physician Performance and Patient Outcomes , 1998 .

[33]  R. Haynes,et al.  Effects of computer-based clinical decision support systems on physician performance and patient outcomes: a systematic review. , 1998, JAMA.

[34]  J D Anderson Increasing the acceptance of clinical information systems. , 1999, M.D. computing : computers in medical practice.

[35]  J. Jespersen,et al.  Multicentre randomised study of computerised anticoagulant dosage , 1998, The Lancet.

[36]  D P Connelly,et al.  Computerized patient records in primary care. Their role in mediating guideline-driven physician behavior change. , 1995, Archives of family medicine.