Ethanol production from renewable resources.

Vast amounts of renewable biomass are available for conversion to liquid fuel, ethanol. In order to convert biomass to ethanol, the efficient utilization of both cellulose-derived and hemicellulose-derived carbohydrates is essential. Six-carbon sugars are readily utilized for this purpose. Pentoses, on the other hand, are more difficult to convert. Several metabolic factors limit the efficient utilization of pentoses (xylose and arabinose). Recent developments in the improvement of microbial cultures provide the versatility of conversion of both hexoses and pentoses to ethanol more efficiently. In addition, novel bioprocess technologies offer a promising prospective for the efficient conversion of biomass and recovery of ethanol.

[1]  John N. Saddler,et al.  Enzyme recycling during fed-batch hydrolysis of cellulose derived from steam-explodedEucalyptus viminalis , 1994 .

[2]  Jean-Philippe Delgenès,et al.  Effects of lignocellulose degradation products on ethanol fermentations of glucose and xylose by Saccharomyces cerevisiae, Zymomonas mobilis, Pichia stipitis, and Candida shehatae , 1996 .

[3]  W. A. Scheffers,et al.  Alcoholic Fermentation of d-Xylose by Yeasts , 1984, Applied and environmental microbiology.

[4]  Y. Y. Lee,et al.  Ammonia-recycled percolation process for pretreatment of biomass feedstock , 1995 .

[5]  T. Conway,et al.  The Entner-Doudoroff pathway: history, physiology and molecular biology. , 1992, FEMS microbiology reviews.

[6]  George T. Tsao,et al.  Production of Ethanol from d-Xylose by Using d-Xylose Isomerase and Yeasts , 1981, Applied and environmental microbiology.

[7]  Melvin P. Tucker,et al.  Dilute acid pretreatment of softwoods , 1998 .

[8]  M. Newman,et al.  Promising ethanologens for xylose fermentation , 1995 .

[9]  Satish K. Garg,et al.  Simultaneous saccharification and fermentation of waste newspaper to ethanol. , 1992 .

[10]  G. T. Tsao,et al.  d-Xylulose Fermentation to Ethanol by Saccharomyces cerevisiae , 1981, Applied and environmental microbiology.

[11]  Y. Y. Lee,et al.  Fractionation of Herbaceous Biomass by Ammonia-Hydrogen Peroxide Percolation Treatment , 1996 .

[12]  G. Stewart,et al.  A study of ethanol tolerance in yeast. , 1990, Critical reviews in biotechnology.

[13]  I. Furusawa,et al.  Temporal Transcriptional Pattern of Three Melanin Biosynthesis Genes, PKS1, SCD1, and THR1, in Appressorium-Differentiating and Nondifferentiating Conidia of Colletotrichum lagenarium , 1997, Applied and environmental microbiology.

[14]  R Marchant,et al.  Isolation of thermotolerant, fermentative yeasts growing at 52°C and producing ethanol at 45°C and 50°C , 1992, World journal of microbiology & biotechnology.

[15]  P. J. Anderson,et al.  High-Efficiency Carbohydrate Fermentation to Ethanol at Temperatures above 40°C by Kluyveromyces marxianus var. marxianus Isolated from Sugar Mills , 1986, Applied and environmental microbiology.

[16]  J. Gould Alkaline peroxide delignification of agricultural residues to enhance enzymatic saccharification , 1984, Biotechnology and bioengineering.

[17]  C. Gong,et al.  Ethanol fermentation in a tower fermenter using self-aggregatingSaccharomyces uvarum , 1994 .

[18]  J. Mcmillan,et al.  Arabinose utilization by xylose-fermenting yeasts and fungi , 1994, Applied biochemistry and biotechnology.

[19]  Cost Estimates and Sensitivity Analyses for the Ammonia Fiber Explosion Process , 1998 .

[20]  Min Zhang,et al.  Advanced Bioethanol Production Technologies: A Perspective , 1997 .

[21]  L. Chen,et al.  Xylan hydrolysis in zinc chloride solution , 1995 .

[22]  R. Torget,et al.  Two-temperature dilute-acid prehydrolysis of hardwood xylan using a percolation process , 1994 .

[23]  B. Saha,et al.  Fuel ethanol production from corn fiber current status and technical prospects , 1998 .

[24]  C. Gong,et al.  Prediction of bed height in a self-aggregating yeast ethanol tower fermenter , 1991 .

[25]  Mark T. Holtzapple,et al.  Lime pretreatment of switchgrass , 1997, Applied biochemistry and biotechnology.

[26]  K. Shanmugam,et al.  Metabolic engineering of Klebsiella oxytoca M5A1 for ethanol production from xylose and glucose , 1991, Applied and environmental microbiology.

[27]  George T. Tsao,et al.  Recent advances in the simultaneous bioreaction and product separation processes , 1993 .

[28]  M. Ladisch,et al.  Growth, death, and oxygen uptake kinetics of Pichia stipitis on xylose , 1991, Biotechnology and bioengineering.

[29]  S. Duff,et al.  Simultaneous hydrolysis and fermentation of pulp mill primary clarifier sludge , 1994 .

[30]  G. T. Tsao,et al.  Production of 2,3- butanediol from pretreated corn cob byKlebsiella oxytoca in the presence of fungal cellulase , 1997, Applied biochemistry and biotechnology.

[31]  Mats Galbe,et al.  The effect of water-soluble inhibitors from steam-pretreated willow on enzymatic hydrolysis and ethanol fermentation , 1996 .

[32]  M. Ladisch,et al.  Cellulose pretreatments of lignocellulosic substrates. , 1994, Enzyme and microbial technology.

[33]  P. Wankat,et al.  An immobilized cell reactor with simultaneous product separation. II. Experimental reactor performance , 1985, Biotechnology and bioengineering.

[34]  G. Philippidis,et al.  Limiting factors in the simultaneous saccharification and fermentation process for conversion of cellulosic biomass to fuel ethanol , 1995 .

[35]  B. Behera,et al.  Solid-state fermentation of new substrates for production of cellulase and other biopolymer-hydrolyzing enzymes , 1995 .

[36]  Mats Galbe,et al.  Comparison of SO2 and H2SO4 impregnation of softwood prior to steam pretreatment on ethanol production , 1998 .

[37]  C. Breuil,et al.  Assessment of pretreatment conditions to obtain fast complete hydrolysis on high substrate concentrations , 1989 .

[38]  L. Ingram,et al.  Effects of environmental conditions on xylose fermentation by recombinant Escherichia coli , 1990, Applied and environmental microbiology.

[39]  Michael R. Ladisch,et al.  Continuous pH monitoring during pretreatment of yellow poplar wood sawdust by pressure cooking in water. , 1998 .

[40]  A. Margaritis,et al.  Isolation and Screening of Yeasts That Ferment d-Xylose Directly to Ethanol , 1985, Applied and environmental microbiology.

[41]  L. Lynd,et al.  Direct microbial conversion , 1992 .

[42]  R. Katzen,et al.  Development of bioconversion of cellulosic wastes , 1995 .

[43]  Li Fu Chen,et al.  Corn hull hydrolysis using glucoamylase and sulfuric acid. , 1984 .

[44]  Mohammed Moniruzzaman,et al.  Enzymatic hydrolysis of high-moisture corn fiber pretreated by afex and recovery and recycling of the enzyme complex , 1997 .

[45]  Recycling of process streams in ethanol production from softwoods based on enzymatic hydrolysis , 1998, Applied biochemistry and biotechnology.

[46]  Bruce E. Dale,et al.  Ethanol production from enzymatic hydrolysates of AFEX-treated coastal bermudagrass and switchgrass , 1995 .

[47]  Michael E. Himmel,et al.  Dilute-Acid Pretreatment of Corn Residues and Short-Rotation Woody Crops , 1991 .

[48]  K. Grohmann,et al.  Fermentation of sugars in organe peel hydrolysates to ethanol by recombinantEscherichia coli KO11 , 1995, Applied biochemistry and biotechnology.

[49]  R. K. Finn,et al.  Fermentation of d-Xylose to Ethanol by Genetically Modified Klebsiella planticola , 1987, Applied and environmental microbiology.

[50]  James D. McMillan,et al.  Pretreatment of lignocellulosic biomass , 1994 .

[51]  L. Ingram,et al.  Efficient ethanol production from glucose, lactose, and xylose by recombinant Escherichia coli , 1989, Applied and environmental microbiology.

[52]  C Shopsis,et al.  Fermentation of a pentose by yeasts. , 1980, Biochemical and biophysical research communications.

[53]  I. Booth,et al.  Regulation of cytoplasmic pH in bacteria. , 1985, Microbiological reviews.

[54]  E. Baldwin,et al.  Production of ethanol from enzymatically hydrolyzed orange peel by the yeastSaccharomyces cerevisiae , 1994, Applied biochemistry and biotechnology.

[55]  D. Schell,et al.  Pretreatment of softwood by acid-catalyzed steam explosion followed by alkali extraction , 1998 .

[56]  Y Y Lee,et al.  Ammonia recycled percolation as a complementary pretreatment to the dilute-acid process , 1997, Applied biochemistry and biotechnology.

[57]  Mark T. Holtzapple,et al.  The ammonia freeze explosion (AFEX) process , 1991 .

[58]  G. P. Van,et al.  Conversion of Lignocellulosics Pretreated With Liquid Hot Water to Ethanol , 1996 .

[59]  A. Lachke,et al.  Effect of nitrogen sources on oxidoreductive enzymes and ethanol production during D-xylose fermentation by Candida shehatae. , 1992, Canadian journal of microbiology.

[60]  B. Dale,et al.  Fermentation of corn fibre sugars by an engineered xylose utilizing Saccharomyces yeast strain , 1997 .

[61]  L. Lynd,et al.  Organism development and characterization for ethanol production using thermophilic bacteria , 1994 .

[62]  D. Mohandas,et al.  Development of xylose-fermenting yeasts for ethanol production at high acetic acid concentrations , 1995 .

[63]  Qu Yinbo,et al.  Cellulase production from spent sulfite liquor and paper-mill waste fiber , 1991 .

[64]  Hwai‐Shen Liu,et al.  Analysis of gas stripping during ethanol fermentation—I. In a continuous stirred tank reactor , 1990 .

[65]  F. Sáez,et al.  Effects of dilute acid and steam explosion pretreatments on the cellulose structure and kinetics of cellulosic fraction hydrolysis by dilute acids in lignocellulosic materials , 1994 .

[66]  George T. Tsao,et al.  Production of ethanol from recycled paper sludge using cellulase and yeast, Kluveromyces marxianus , 1997 .

[67]  L. Lynd Large-scale fuel ethanol from lignocellulose , 1990 .

[68]  J N Saddler,et al.  Evaluation of cellulase recycling strategies for the hydrolysis of lignocellulosic substrates , 1995, Biotechnology and bioengineering.

[69]  Michael Jerry Antal,et al.  Uncatalyzed solvolysis of whole biomass hemicellulose by hot compressed liquid water , 1992 .

[70]  Karel Grohmann,et al.  Saccharification of corn fibre by combined treatment with dilute sulphuric acid and enzymes , 1997 .

[71]  Pamela J. Walter,et al.  A technical and economic analysis of acid-catalyzed steam explosion and dilute sulfuric acid pretreatments using wheat straw or aspen wood chips , 1991 .

[72]  R. Elander,et al.  Processing and economic impacts of biomass delignification for ethanol production , 1995 .

[73]  J. Kastner,et al.  Viability of Candida shehatae in D-xylose fermentations with added ethanol. , 1992, Biotechnology and bioengineering.

[74]  Min Zhang,et al.  Metabolic Engineering of a Pentose Metabolism Pathway in Ethanologenic Zymomonas mobilis , 1995, Science.

[75]  Effect of sugar consumption on ethanol fermentation in a tower fermentor packed with self-aggregating yeast , 1993 .

[76]  Sung Bae Kim,et al.  Ammonia recycled percolation process for pretreatment of herbaceous biomass , 1996 .

[77]  C. Gong,et al.  Cellulose hydrolysis using zinc chloride as a solvent and catalyst , 1994 .

[78]  Brian H. Davison,et al.  An advanced bioprocessing concept for the conversion of waste paper to ethanol , 1994 .

[79]  J. Lema,et al.  Ethanolic fermentation by immobilized Saccharomyces cerevisiae in a semipilot pulsing packed-bed bioreactor , 1996 .

[80]  Christos Hatzis,et al.  Optimization of reverse-flow, two-temperature, dilute-acid pretreatment to enhance biomass conversion to ethanol , 1996 .