Single breath‐hold whole‐heart MRA using variable‐density spirals at 3t

Multislice breath‐held coronary imaging techniques conventionally lack the coverage of free‐breathing 3D acquisitions but use a considerably shorter acquisition window during the cardiac cycle. This produces images with significantly less motion artifact but a lower signal‐to‐noise ratio (SNR). By using the extra SNR available at 3 T and undersampling k‐space without introducing significant aliasing artifacts, we were able to acquire high‐resolution fat‐suppressed images of the whole heart in 17 heartbeats (a single breath‐hold). The basic pulse sequence consists of a spectral‐spatial excitation followed by a variable‐density spiral readout. This is combined with real‐time localization and a real‐time prospective shim correction. Images are reconstructed with the use of gridding, and advanced techniques are used to reduce aliasing artifacts. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.

[1]  D Matthaei,et al.  1H NMR chemical shift selective (CHESS) imaging. , 1985, Physics in medicine and biology.

[2]  Peter Boesiger,et al.  Sensitivity‐encoded coronary MRA at 3T , 2004, Magnetic resonance in medicine.

[3]  René M. Botnar,et al.  Coronary magnetic resonance angiography for the detection of coronary stenoses. , 2001, The New England journal of medicine.

[4]  Dwight G Nishimura,et al.  Spiral magnetic resonance coronary angiography with rapid real-time localization. , 2003, Journal of the American College of Cardiology.

[5]  Volker Rasche,et al.  Resampling of data between arbitrary grids using convolution interpolation , 1999, IEEE Transactions on Medical Imaging.

[6]  J. Pauly,et al.  A homogeneity correction method for magnetic resonance imaging with time-varying gradients. , 1991, IEEE transactions on medical imaging.

[7]  René M. Botnar,et al.  Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography. , 1999, Journal of the American College of Cardiology.

[8]  A Macovski,et al.  Echo‐planar spin‐echo and inversion pulses , 1993, Magnetic resonance in medicine.

[9]  Bob S. Hu,et al.  Fast Spiral Coronary Artery Imaging , 1992, Magnetic resonance in medicine.

[10]  D. Spielman,et al.  Dynamic shimming for multi‐slice magnetic resonance imaging , 1997, Magnetic resonance in medicine.

[11]  M B Scheidegger,et al.  Coronary artery imaging in multiple 1-sec breath holds. , 1993, Magnetic resonance imaging.

[12]  P. Boesiger,et al.  Advances in sensitivity encoding with arbitrary k‐space trajectories , 2001, Magnetic resonance in medicine.

[13]  K F King,et al.  Concomitant gradient field effects in spiral scans , 1999, Magnetic resonance in medicine.

[14]  Yiping P. Du,et al.  Correction of concomitant magnetic field‐induced image artifacts in nonaxial echo‐planar imaging , 2002, Magnetic resonance in medicine.

[15]  Dwight G Nishimura,et al.  Journal of Cardiovascular Magnetic Resonance Dynamic Real-time Architecture in Magnetic Resonance Coronary Angiography—a Prospective Clinical Trial , 2022 .

[16]  Thoralf Niendorf,et al.  Short breath‐hold, volumetric coronary MR angiography employing steady‐state free precession in conjunction with parallel imaging , 2005, Magnetic resonance in medicine.

[17]  J. Pipe Reconstructing MR images from undersampled data: Data‐weighting considerations , 2000, Magnetic resonance in medicine.

[18]  Jeffrey A. Fessler,et al.  Nonuniform fast Fourier transforms using min-max interpolation , 2003, IEEE Trans. Signal Process..

[19]  D G Nishimura,et al.  Inhomogeneity correction using an estimated linear field map , 1996, Magnetic resonance in medicine.

[20]  René M. Botnar,et al.  Comparison of fat suppression strategies in 3D spiral coronary magnetic resonance angiography , 2002, Journal of magnetic resonance imaging : JMRI.

[21]  Y Zur Design of improved spectral‐spatial pulses for routine clinical use , 2000, Magnetic resonance in medicine.

[22]  Alastair J. Martin,et al.  Whole‐heart steady‐state free precession coronary artery magnetic resonance angiography , 2003, Magnetic resonance in medicine.

[23]  A. Macovski,et al.  Selection of a convolution function for Fourier inversion using gridding [computerised tomography application]. , 1991, IEEE transactions on medical imaging.

[24]  René M. Botnar,et al.  Preliminary report on in vivo coronary MRA at 3 Tesla in humans , 2002, Magnetic resonance in medicine.

[25]  Juan M. Santos,et al.  Real‐time cardiac MRI at 3 tesla , 2004, Magnetic resonance in medicine.

[26]  A. Macovski,et al.  Variable-rate selective excitation , 1988 .

[27]  Osman Ratib,et al.  OsiriX: An Open-Source Software for Navigating in Multidimensional DICOM Images , 2004, Journal of Digital Imaging.

[28]  G. Glover,et al.  Regularized higher‐order in vivo shimming , 2002, Magnetic resonance in medicine.

[29]  René M. Botnar,et al.  Impact of bulk cardiac motion on right coronary MR angiography and vessel wall imaging , 2001, Journal of magnetic resonance imaging : JMRI.

[30]  Michael Lustig,et al.  Faster Imaging with Randomly Perturbed, Undersampled Spirals and |L|_1 Reconstruction , 2004 .

[31]  Todd S. Sachs,et al.  The diminishing variance algorithm for real‐time reduction of motion artifacts in MRI , 1995, Magnetic resonance in medicine.

[32]  D. Nishimura,et al.  Reduced aliasing artifacts using variable‐density k‐space sampling trajectories , 2000, Magnetic resonance in medicine.

[33]  Dwight G Nishimura,et al.  Time‐optimal multidimensional gradient waveform design for rapid imaging , 2004, Magnetic resonance in medicine.

[34]  Alexander M. Bronstein,et al.  Reconstruction in diffraction ultrasound tomography using nonuniform FFT , 2002, IEEE Transactions on Medical Imaging.

[35]  J. Pauly,et al.  Simultaneous spatial and spectral selective excitation , 1990, Magnetic resonance in medicine.

[36]  A Macovski,et al.  Multifrequency interpolation for fast off‐resonance correction , 1997, Magnetic resonance in medicine.

[37]  H. Rinneberg,et al.  Human cardiac imaging at 3 T using phased array coils , 2000, Magnetic resonance in medicine.