Genetic Toxicology and Cancer Risk Assessment

Human Cancer Genetics Jason W. Barlow and David Malkin Genetic Toxicity Tests for Predicting Carcinogenicity Errol Zeiger Genotoxic and Nongenotoxic Mechanisms of Carcinogenesis Wai Nang Choy Structure-Activity Relationship (SAR) and its Roles in Cancer Risk Assessment David Y. Lai and Yin-tak Woo Regulatory Genetic Toxicology Tests Wai Nang Choy Complementary Genetic Toxicology Assays B. Bhaskar Gollapudi The Mouse Lymphoma Assay (MLA) Using the Microwell Method Masamitsu Honma and Toshio Sofuni The In Vitro Micronucleus Assay Marilyn J. Aardema and Micheline Kirsch-Volders ICH Guidelines on Genotoxicity and Carcinogenicity: Scientific Background and Regulatory Practice Lutz Muller, Peter Kasper, and Leonard Schechtman New OECD Genetic Toxicology Guidelines and Interpretation of Results Michael C. Cimino Dose-Response Relationships in Chemical Carcinogenesis and Cancer Risk Assessment Werner K. Lutz Molecular Epidemiology and Biomarkers Jia-Sheng Wang, Jonathan M. Links, John Groopman Quantitative Cancer Risk Assessment of Nongenotoxic Carcinogens Anna M. Fan and Robert A. Howd Risk Assessment of Genotoxic Carcinogens Lauren Zeise Biologically Based Cancer Risk Assessment Models Suresh H. Moolgavkar