Responsibility of sport and exercise medicine in preventing and managing chronic disease: applying our knowledge and skill is overdue

Background The rapidly increasing burden of chronic disease is difficult to reconcile with the large, compelling body of literature that demonstrates the substantial preventive and therapeutic benefits of comprehensive lifestyle intervention, including physical activity, smoking cessation and healthy diet. Physical inactivity is now the fourth leading independent risk factor for death caused by non-communicable chronic disease. Although there have been efforts directed towards research, education and legislation, preventive efforts have been meager relative to the magnitude of the problem. The disparity between our scientific knowledge about chronic disease and practical implementation of preventive approaches now is one of the most urgent concerns in healthcare worldwide and threatens the collapse of our health systems unless extraordinary change takes place. Findings The authors believe that there are several key factors contributing to the disparity. Reductionism has become the default approach for healthcare delivery, resulting in fragmentation rather than integration of services. This, in turn, has fostered a disease-based rather than a health-based model of care and has produced medical school curricula that no longer accurately reflect the actual burden of disease. Trying to ‘fit’ prevention into a disease-based approach has been largely unsuccessful because the fundamental tenets of preventive medicine are diametrically opposed to those of disease-based healthcare. Recommendation A clinical discipline within medicine is needed to adopt disease prevention as its own reason for existence. Sport and exercise medicine is well positioned to champion the cause of prevention by promoting physical activity. Conclusion This article puts forward a strong case for the immediate, increased involvement of clinical sport and exercise medicine in the prevention and treatment of chronic disease and offers specific recommendations for how this may begin.

[1]  L. Shulman,et al.  THE CARNEGIE FOUNDATION FOR THE ADVANCEMENT OF TEACHING. , 1909, Science.

[2]  Abraham Flexner,et al.  MEDICAL EDUCATION IN THE UNITED STATES AND CANADA. , 1910, Science.

[3]  Functions and structure of a Medical School. , 1974, Connecticut medicine.

[4]  W. Kannel,et al.  Some health benefits of physical activity. The Framingham Study. , 1979, Archives of internal medicine.

[5]  M. Everitt,et al.  VIGOROUS EXERCISE IN LEISURE-TIME: PROTECTION AGAINST CORONARY HEART DISEASE , 1980, The Lancet.

[6]  John A. H. Lee Health: United States , 1986 .

[7]  Barbara Gastel,et al.  Learning to Heal: The Development of American Medical Education , 1986 .

[8]  J. Morris,et al.  Exercise in leisure time: coronary attack and death rates. , 1990, British heart journal.

[9]  R. Paffenbarger,et al.  Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. , 1991, The New England journal of medicine.

[10]  S. Abrahamson The dominance of research in staffing of medical schools: time for a change? , 1991, The Lancet.

[11]  H. Ireys,et al.  Who enrolls in prevention trials? Discordance in perception of risk by professionals and participants , 1991, American journal of community psychology.

[12]  H. Holman,et al.  What's preventing more prevention? Barriers to development at academic medical centers. , 1992, Journal of general internal medicine.

[13]  McGinnis Jm,et al.  Actual causes of death in the United States. , 1993 .

[14]  R S Paffenbarger,et al.  The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. , 1993, The New England journal of medicine.

[15]  C. Bouchard,et al.  Physical Activity, Fitness, and Health: International Proceedings and Consensus Statement , 1994 .

[16]  W. Rakowski,et al.  Stages of change and decisional balance for 12 problem behaviors. , 1994, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[17]  P. Blackman Actual causes of death in the United States. , 1994, JAMA.

[18]  K. Patrick,et al.  Physical Activity and Public Health: A Recommendation From the Centers for Disease Control and Prevention and the American College of Sports Medicine , 1995 .

[19]  P. Williams,et al.  Physical activity and public health. , 1995, JAMA.

[20]  A. Prentice,et al.  Obesity in Britain: gluttony or sloth? , 1995, BMJ.

[21]  A. Laupacis,et al.  A study of the quality of life and cost-utility of renal transplantation. , 1996, Kidney international.

[22]  S. Abrahamson Time to return medical schools to their primary purpose: education , 1996, Academic medicine : journal of the Association of American Medical Colleges.

[23]  J. Ockene,et al.  Effect of training and a structured office practice on physician-delivered nutrition counseling: the Worcester-Area Trial for Counseling in Hyperlipidemia (WATCH). , 1996, American journal of preventive medicine.

[24]  Claude Bouchard,et al.  Physical Activity, Fitness, and Health , 1997 .

[25]  P. Naylor,et al.  Barriers to physical activity promotion by general practitioners and practice nurses. , 1998, British journal of sports medicine.

[26]  S Goya Wannamethee,et al.  Changes in physical activity, mortality, and incidence of coronary heart disease in older men , 1998, The Lancet.

[27]  B H Marcus,et al.  Physical activity interventions using mass media, print media, and information technology. , 1998, American journal of preventive medicine.

[28]  T. Baranowski,et al.  Mediating variable framework in physical activity interventions. How are we doing? How might we do better? , 1998, American journal of preventive medicine.

[29]  A S Jackson,et al.  Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men. , 1999, The American journal of clinical nutrition.

[30]  D. Abrams,et al.  The efficacy of exercise as an aid for smoking cessation in women: a randomized controlled trial. , 1999, Archives of internal medicine.

[31]  J. Hyndman,et al.  Nutritional counselling in general practice: a cost effective analysis. , 1999, Journal of epidemiology and community health.

[32]  C. Friedenreich,et al.  Physical exercise and quality of life following cancer diagnosis: A literature review , 1999, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[33]  J. D'ivernois,et al.  [How do physicians evaluate their medical school training. Retrospective survey of 4 groups of medical students 8-11 years after graduation]. , 1999, Presse medicale.

[34]  Kenneth M. Ludmerer,et al.  Learning to Heal: The Development of American Medical Education , 1999, Nursing History Review.

[35]  Ted O’Donoghue,et al.  Doing It Now or Later , 1999 .

[36]  D. Lackland,et al.  Prevention Education and Evaluation in U.S. Medical Schools: A Status Report , 2000, Academic medicine : journal of the Association of American Medical Colleges.

[37]  Sj Wu,et al.  A Projection of Chronic Illness Prevalence and Cost Inflation , 2000 .

[38]  N. Owen,et al.  Promoting physical activity: the new imperative for public health. , 2000, Health education research.

[39]  Mary V. Davis,et al.  Prevention for the 21st Century: Setting the Context through Undergraduate Medical Education , 2000, Academic medicine : journal of the Association of American Medical Colleges.

[40]  C R Nigg,et al.  Interactive communication strategies: implications for population-based physical-activity promotion. , 2000, American journal of preventive medicine.

[41]  F. Rasmussen,et al.  Low physical fitness in childhood is associated with the development of asthma in young adulthood: the Odense schoolchild study. , 2000, The European respiratory journal.

[42]  M T Rabkin,et al.  Will disruptive innovations cure health care? , 2001, Harvard business review.

[43]  S. Norris,et al.  Effectiveness of self-management training in type 2 diabetes: a systematic review of randomized controlled trials. , 2001, Diabetes care.

[44]  J. Kampert,et al.  Usefulness of cardiorespiratory fitness as a predictor of all-cause and cardiovascular disease mortality in men with systemic hypertension. , 2001, The American journal of cardiology.

[45]  S. Blair,et al.  Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men. , 1999, The American journal of clinical nutrition.

[46]  J. Knottnerus,et al.  Asymptomatic peripheral arterial occlusive disease predicted cardiovascular morbidity and mortality in a 7-year follow-up study. , 2004, Journal of clinical epidemiology.

[47]  J. Epping-Jordan,et al.  Innovative care for chronic conditions: building blocks for action , 2002 .

[48]  C. T. Orleans,et al.  Evaluating primary care behavioral counseling interventions: an evidence-based approach. , 2002, American journal of preventive medicine.

[49]  A. Flexner Medical education in the United States and Canada. From the Carnegie Foundation for the Advancement of Teaching, Bulletin Number Four, 1910. , 2002, Bulletin of the World Health Organization.

[50]  Kurt C Stange,et al.  One minute for prevention: the power of leveraging to fulfill the promise of health behavior counseling. , 2002, American journal of preventive medicine.

[51]  C. Mulrow,et al.  Does Counseling by Clinicians Improve Physical Activity? A Summary of the Evidence for the U.S. Preventive Services Task Force , 2002, Annals of Internal Medicine.

[52]  J. Garry,et al.  Physical Activity Curricula in Medical Schools , 2002, Academic medicine : journal of the Association of American Medical Colleges.

[53]  S. Fowler,et al.  Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. , 2002 .

[54]  C. Tudor-Locke,et al.  Preliminary outcome evaluation of the First Step Program: a daily physical activity intervention for individuals with type 2 diabetes. , 2002, Patient education and counseling.

[55]  R. Goetzel,et al.  The Long-Term Impact of Johnson & Johnson’s Health & Wellness Program on Employee Health Risks , 2002, Journal of occupational and environmental medicine.

[56]  Thomas Bodenheimer,et al.  Improving primary care for patients with chronic illness: the chronic care model, Part 2. , 2002, JAMA.

[57]  Michael J Thun,et al.  Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. , 2003, The New England journal of medicine.

[58]  A. Folsom,et al.  Physical Activity and Stroke Risk: A Meta-Analysis , 2003, Stroke.

[59]  Alison L Marshall,et al.  Print versus website physical activity programs: a randomized trial. , 2003, American journal of preventive medicine.

[60]  R. Berenson,et al.  Confronting the barriers to chronic care management in Medicare. , 2003, Health affairs.

[61]  David R Bassett,et al.  Physical activity in an Old Order Amish community. , 2004, Medicine and science in sports and exercise.

[62]  Nick Cavill,et al.  Changing the way people think about health-enhancing physical activity: do mass media campaigns have a role? , 2004, Journal of sports sciences.

[63]  Jeannine S. Schiller,et al.  Summary health statistics for U.S. adults: National Health Interview Survey, 2002. , 2004, Vital and health statistics. Series 10, Data from the National Health Survey.

[64]  D. Purdie,et al.  Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fasting insulin, and quality of life , 2004, Gut.

[65]  Meghan L Butryn,et al.  Efficacy of lifestyle modification for long-term weight control. , 2004, Obesity research.

[66]  Abdullah Alkenizan,et al.  Innovative care for chronic conditions: building blocks for action , 2004, Annals of Saudi Medicine.

[67]  W. Stalman,et al.  Feasibility and acceptability of a physical activity promotion programme in general practice. , 2004, Family practice.

[68]  W. Willett,et al.  Physical activity and risk of coronary heart disease in India. , 2004, International journal of epidemiology.

[69]  P. Ginsburg,et al.  When the price isn't right: how inadvertent payment incentives drive medical care. , 2005, Health affairs.

[70]  E. Finkelstein,et al.  The Costs of Obesity among Full-Time Employees , 2005, American journal of health promotion : AJHP.

[71]  L. Anderson,et al.  Aging and public health: partnerships that can affect cardiovascular health programs. , 2005, American journal of preventive medicine.

[72]  Ben J. Smith,et al.  Evaluating the Population Health Impact of Physical Activity Interventions in Primary Care—Are We Asking the Right Questions? , 2005 .

[73]  Katrina M. Krause,et al.  Is There Time for Management of Patients With Chronic Diseases in Primary Care? , 2005, The Annals of Family Medicine.

[74]  David L Katz,et al.  Physical activity counseling in the adult primary care setting: position statement of the American College of Preventive Medicine. , 2005, American journal of preventive medicine.

[75]  S. Studenski,et al.  Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults , 2006, Journal of the American Geriatrics Society.

[76]  B. Popkin,et al.  Measuring the full economic costs of diet, physical activity and obesity‐related chronic diseases , 2006, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[77]  C. Mathers,et al.  Projections of Global Mortality and Burden of Disease from 2002 to 2030 , 2006, PLoS medicine.

[78]  Hugh Tunstall-Pedoe,et al.  Preventing Chronic Diseases. A Vital Investment: WHO Global Report. Geneva: World Health Organization, 2005. pp 200. CHF 30.00. ISBN 92 4 1563001. Also published on http://www.who.int/chp/chronic_disease_report/en/ , 2006 .

[79]  J Lyle Bootman,et al.  Value in health care. , 2006, Managed care interface.

[80]  W. Kroeze,et al.  A systematic review of randomized trials on the effectiveness of computer-tailored education on physical activity and dietary behaviors , 2006, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[81]  M. Tewari,et al.  The Limits of Reductionism in Medicine: Could Systems Biology Offer an Alternative? , 2006, PLoS medicine.

[82]  P. Tugwell,et al.  Applying clinical epidemiological methods to health equity: the equity effectiveness loop , 2006, BMJ : British Medical Journal.

[83]  M. Tewari,et al.  The Clinical Applications of a Systems Approach , 2006, PLoS medicine.

[84]  D. Taaffe Sarcopenia--exercise as a treatment strategy. , 2006, Australian family physician.

[85]  Molly Cooke,et al.  American medical education 100 years after the Flexner report. , 2006, The New England journal of medicine.

[86]  Heather K. Neilson,et al.  Re: "Influence of exercise, walking, cycling, and overall nonexercise physical activity on mortality in Chinese women". , 2007, American journal of epidemiology.

[87]  C. Matthews,et al.  Influence of exercise, walking, cycling, and overall nonexercise physical activity on mortality in Chinese women. , 2007, American journal of epidemiology.

[88]  Sérgio Tufik,et al.  The impact of resistance exercise on the cognitive function of the elderly. , 2007, Medicine and science in sports and exercise.

[89]  M. H. van den Berg,et al.  Internet-Based Physical Activity Interventions: A Systematic Review of the Literature , 2007, Journal of medical Internet research.

[90]  S. Thompson,et al.  Establishing health promotion in the modern medical curriculum: a case study , 2007, Medical teacher.

[91]  Hoangmai H Pham,et al.  Unhealthy trends: the future of physician services. , 2007, Health affairs.

[92]  Taghreed Adam,et al.  The burden and costs of chronic diseases in low-income and middle-income countries , 2007, The Lancet.

[93]  S. Wilcox,et al.  Physical activity interventions in clinical settings , 2007 .

[94]  R. Shephard,et al.  [Evidence-based guidelines for physical activity of adult Canadians]. , 2007, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[95]  A. Bauman,et al.  Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. , 2007, Circulation.

[96]  J. Rizzo,et al.  Occupation-Specific Absenteeism Costs Associated With Obesity and Morbid Obesity , 2007, Journal of occupational and environmental medicine.

[97]  Stephen Colagiuri,et al.  Grand challenges in chronic non-communicable diseases , 2007, Nature.

[98]  C. Vandelanotte,et al.  Website-delivered physical activity interventions a review of the literature. , 2007, American journal of preventive medicine.

[99]  L. Mâsse,et al.  Physical activity in the United States measured by accelerometer. , 2008, Medicine and science in sports and exercise.

[100]  Donna M Gates,et al.  Obesity and Presenteeism: The Impact of Body Mass Index on Workplace Productivity , 2008, Journal of occupational and environmental medicine.

[101]  R. Moynihan Doctors’ education: the invisible influence of drug company sponsorship , 2008, BMJ : British Medical Journal.

[102]  Jiaquan Xu,et al.  Deaths: final data for 2005. , 2008, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[103]  M. Schwellnus,et al.  Healthy lifestyle interventions in general practice , 2008 .

[104]  Clayton M. Christensen,et al.  The Innovator's Prescription: A Disruptive Solution for Health Care , 2008 .

[105]  W. Mechelen Effectiveness and economic impact of worksite interventions to promote physical activity and healthy diet Background paper prepared for the WHO / WEF Joint Event on Preventing Noncommunicable Diseases in the Workplace ( Dalian / China , September 2007 ) , 2008 .

[106]  C. Braddock,et al.  Integrating collaborative population health projects into a medical student curriculum at Stanford. , 2008, Academic medicine : journal of the Association of American Medical Colleges.

[107]  Contributions from M. Walpole The Millennium Development Goals Report , 2008 .

[108]  R. Rhodes,et al.  Do government brochures affect physical activity cognition? A pilot study of Canada's physical activity guide to healthy active living , 2008, Psychology, health & medicine.

[109]  Isaac S Kohane,et al.  Tectonic shifts in the health information economy. , 2008, The New England journal of medicine.

[110]  R. Ross,et al.  Prevention and Reduction of Obesity through Active Living (PROACTIVE): rationale, design and methods , 2008, British Journal of Sports Medicine.

[111]  H. Stefánsson,et al.  Genetics of gene expression and its effect on disease , 2008, Nature.

[112]  Benjamin Caballero,et al.  Will All Americans Become Overweight or Obese? Estimating the Progression and Cost of the US Obesity Epidemic , 2008, Obesity.

[113]  F. Lobelo,et al.  Physical activity habits of doctors and medical students influence their counselling practices , 2008, British Journal of Sports Medicine.

[114]  A. Ståhle,et al.  Physical activity on prescription in primary health care: a follow‐up of physical activity level and quality of life , 2007, Scandinavian journal of medicine & science in sports.

[115]  Jennifer S. Carrera,et al.  Physical activity levels and counseling practices of U.S. medical students. , 2008, Medicine and science in sports and exercise.

[116]  J. Lucas,et al.  Summary health statistics for U.S. adults: National Health Interview Survey, 2008. , 2009, Vital and health statistics. Series 10, Data from the National Health Survey.

[117]  Ramy Arnaout,et al.  Customized care 2020: how medical sequencing and network biology will enable personalized medicine , 2009, F1000 biology reports.

[118]  Roger Martin The Design of Business: Why Design Thinking is the Next Competitive Advantage , 2009 .

[119]  A. Stagnaro-Green,et al.  Teaching behavior change concepts and skills during the third-year medicine clerkship. , 2009, Academic medicine : journal of the Association of American Medical Colleges.

[120]  L. Neville,et al.  Computer-tailored dietary behaviour change interventions: a systematic review , 2009, Health education research.

[121]  A. Ståhle,et al.  Beneficial effects of individualized physical activity on prescription on body composition and cardiometabolic risk factors: results from a randomized controlled trial , 2009, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

[122]  Charles Abraham,et al.  Are worksite interventions effective in increasing physical activity? A systematic review and meta-analysis , 2009 .

[123]  R. Scharff Obesity and Hyperbolic Discounting: Evidence and Implications , 2009 .

[124]  Lawrence O Gostin,et al.  Evolving from reductionism to holism: is there a future for systems medicine? , 2009, JAMA.

[125]  G. Brunello,et al.  The Rise of Obesity in Europe: An Economic Perspective , 2009 .

[126]  V. Gqamane The Millennium Development Goals Report, 2009 , 2009 .

[127]  C F Finch,et al.  A sports setting matrix for understanding the implementation context for community sport , 2009, British Journal of Sports Medicine.

[128]  Steven Jonas,et al.  ACSM's Exercise is Medicine™: A Clinician's Guide to Exercise Prescription , 2009 .

[129]  M. Schulzer,et al.  Effect of school-based physical activity interventions on body mass index in children: a meta-analysis , 2009, Canadian Medical Association Journal.

[130]  R. Bohmer Designing Care: Aligning the Nature and Management of Health Care , 2009 .

[131]  Elena Rusticelli,et al.  The Obesity Epidemic: Analysis of Past and Projected Future Trends in Selected OECD Countries , 2009 .

[132]  N. Lins,et al.  New frontiers for the sustainable prevention and control of non-communicable diseases (NCDs): a view from sub-Saharan Africa , 2010, Global health promotion.

[133]  J. Dvořák,et al.  Football for health – prevention is better than cure , 2010, Scandinavian journal of medicine & science in sports.

[134]  Quality Measures and the Individual Physician , 2010 .

[135]  Franco Sassi,et al.  Obesity and the Economics of Prevention , 2010 .

[136]  G. Matheson,et al.  The Prevention of Sport Injury: An Analysis of 12 000 Published Manuscripts , 2010, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[137]  J. Lucas,et al.  Summary health statistics for U.S. adults: National Health Interview Survey, 2009. , 2010, Vital and health statistics. Series 10, Data from the National Health Survey.

[138]  Jennifer S. Lin,et al.  Behavioral Counseling to Promote Physical Activity and a Healthful Diet to Prevent Cardiovascular Disease in Adults: A Systematic Review for the U.S. Preventive Services Task Force , 2010, Annals of Internal Medicine.

[139]  Hoangmai H Pham,et al.  Episode-Based Payments: Charting a Course for Health Care Payment Reform. Washington, DC: National Institute for Health Care Reform , 2010 .

[140]  Franco Sassi,et al.  Obesity and the Economics of Prevention: Fit Not Fat , 2010 .

[141]  M. Fain,et al.  Healthy Aging Rounds: Using Healthy‐Aging Mentors to Teach Medical Students About Physical Activity and Social Support Assessment, Interviewing, and Prescription , 2010, Journal of the American Geriatrics Society.

[142]  B. Gersh Modelling the decreasing coronary heart disease mortality in Sweden between 1986 and 2002 , 2010 .

[143]  R. Rhodes,et al.  Mediators of physical activity behaviour change among adult non-clinical populations: a review update , 2010, The international journal of behavioral nutrition and physical activity.

[144]  A. Junge,et al.  ‘Football for Health’—a football-based health-promotion programme for children in South Africa: a parallel cohort study , 2010, British Journal of Sports Medicine.

[145]  Allard J van der Beek,et al.  Sustained body weight reduction by an individual-based lifestyle intervention for workers in the construction industry at risk for cardiovascular disease: results of a randomized controlled trial. , 2010, Preventive medicine.

[146]  Albert-László Barabási,et al.  Limits of Predictability in Human Mobility , 2010, Science.

[147]  Willem van Mechelen,et al.  Sedentary behaviors and health outcomes among adults: a systematic review of prospective studies. , 2011, American journal of preventive medicine.

[148]  C. Sundberg,et al.  Physical activity as medicine: time to translate evidence into clinical practice , 2011, British Journal of Sports Medicine.

[149]  A. Junge,et al.  ‘11 for Health’, a football-based health education programme for children: a two-cohort study in Mauritius and Zimbabwe , 2011, British Journal of Sports Medicine.

[150]  Claude Bouchard,et al.  Trends over 5 Decades in U.S. Occupation-Related Physical Activity and Their Associations with Obesity , 2011, PloS one.

[151]  Charles Boelen,et al.  Consenso Global sobre la Responsabilidad Social de las Facultades de Medicina , 2011 .

[152]  J. Haerting,et al.  Prevention and health promotion in undergraduate medical education: Preferences, attitudes and previous knowledge of medical students - a cross-sectional study , 2011, GMS Zeitschrift fur medizinische Ausbildung.

[153]  A. Dans,et al.  The rise of chronic non-communicable diseases in southeast Asia: time for action , 2011, The Lancet.

[154]  D. Hughes,et al.  Weight Lifting for Women at Risk for Breast Cancer–Related Lymphedema: A Randomized Trial , 2011 .

[155]  D. Makuc,et al.  Health, United States, 2010; with special feature on death and dying , 2011 .

[156]  Robert W Snow,et al.  The effect of mobile phone text-message reminders on Kenyan health workers' adherence to malaria treatment guidelines: a cluster randomised trial , 2011, The Lancet.

[157]  E. Stamatakis,et al.  Medicolegal neglect? The case for physical activity promotion and Exercise Medicine , 2011, British Journal of Sports Medicine.

[158]  Yu-fei Li,et al.  Sarcopenia , 2011 .

[159]  K. Khan The girl with or without tattoos who lived happily ever after because of ‘physical activity on prescription’: the fourth in the Stieg Larsson Trilogy , 2011, British Journal of Sports Medicine.

[160]  C. Boelen [Global consensus on social accountability of medical schools]. , 2011, Sante publique.

[161]  C. Finch Implementation and dissemination research: the time has come! , 2011, British Journal of Sports Medicine.

[162]  P. Allotey,et al.  Rethinking health-care systems: a focus on chronicity , 2011, The Lancet.

[163]  G. Paradis The Imperative of Public Health , 2013 .