Decreased Expression of Adipogenic Genes in Obese Subjects with Type 2 Diabetes

[1]  K. Hua,et al.  Protein inhibitor of activated STAT3 inhibits adipogenic gene expression. , 2006, Biochemical and biophysical research communications.

[2]  C. Kahn,et al.  Intrinsic Heterogeneity in Adipose Tissue of Fat-specific Insulin Receptor Knock-out Mice Is Associated with Differences in Patterns of Gene Expression* , 2004, Journal of Biological Chemistry.

[3]  A. Goldberg,et al.  Racial differences in adipocyte size and relationship to the metabolic syndrome in obese women. , 2004, Obesity research.

[4]  B. Falkner,et al.  Race/ethnic issues in obesity and obesity-related comorbidities. , 2004, The Journal of clinical endocrinology and metabolism.

[5]  Maia M. Jack,et al.  Evidence of impaired adipogenesis in insulin resistance. , 2004, Biochemical and biophysical research communications.

[6]  M. Lazar,et al.  Transcriptional control of adipogenesis. , 2003, Annual review of nutrition.

[7]  J. Auwerx,et al.  Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[8]  S. Kwak,et al.  NF-κB is involved in the TNF-α induced inhibition of the differentiation of 3T3-L1 cells by reducing PPARγ expression , 2003, Experimental & Molecular Medicine.

[9]  Karen C Johnson,et al.  Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. , 2003, Controlled clinical trials.

[10]  J. Stephens,et al.  STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation. , 2003, Diabetes.

[11]  E. Rosen The Molecular Control of Adipogenesis, with Special Reference to Lymphatic Pathology , 2002, Annals of the New York Academy of Sciences.

[12]  C. Kahn,et al.  Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. , 2002, Developmental cell.

[13]  Y. Masuho,et al.  Stimulation of 3T3-L1 adipogenesis by signal transducer and activator of transcription 5. , 2002, Molecular endocrinology.

[14]  S. O’Rahilly,et al.  Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha. , 2002, Diabetes.

[15]  E. A. Sims,et al.  Are there persons who are obese, but metabolically healthy? , 2001, Metabolism: clinical and experimental.

[16]  M. Laville,et al.  Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. , 2001, Diabetes.

[17]  J. Gimble,et al.  Differential expression of signal transducers and activators of transcription during human adipogenesis. , 2001, Biochemical and biophysical research communications.

[18]  T. Willson,et al.  Comprehensive Messenger Ribonucleic Acid Profiling Reveals That Peroxisome Proliferator-Activated Receptor γ Activation Has Coordinate Effects on Gene Expression in Multiple Insulin-Sensitive Tissues. , 2001, Endocrinology.

[19]  C. Bogardus,et al.  Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance , 2000, Diabetologia.

[20]  E. Danforth Failure of adipocyte differentiation causes type II diabetes mellitus? , 2000, Nature Genetics.

[21]  P. Puigserver,et al.  Transcriptional regulation of adipogenesis. , 2000, Genes & development.

[22]  A. Folsom,et al.  Incident type 2 diabetes mellitus in African American and white adults: the Atherosclerosis Risk in Communities Study. , 2000, JAMA.

[23]  P. Kopelman Obesity as a medical problem , 2000, Nature.

[24]  G. Shulman,et al.  Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice* , 2000, The Journal of Biological Chemistry.

[25]  M. Reitman,et al.  Transgenic Mice Lacking White Fat: Models for Understanding Human Lipoatrophic Diabetes , 1999, Annals of the New York Academy of Sciences.

[26]  W. Wahli,et al.  Peroxisome proliferator-activated receptors: nuclear control of metabolism. , 1999, Endocrine reviews.

[27]  R. Hammer,et al.  Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy , 1999, Nature.

[28]  B. Spiegelman,et al.  Regulation of Peroxisome Proliferator-Activated Receptor γ Expression by Adipocyte Differentiation and Determination Factor 1/Sterol Regulatory Element Binding Protein 1: Implications for Adipocyte Differentiation and Metabolism , 1999, Molecular and Cellular Biology.

[29]  H. King,et al.  Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections , 1998, Diabetes Care.

[30]  B. Spiegelman,et al.  ADD1/SREBP1 activates PPARγ through the production of endogenous ligand , 1998 .

[31]  K. Flegal,et al.  Prevalence of Diabetes, Impaired Fasting Glucose, and Impaired Glucose Tolerance in U.S. Adults: The Third National Health and Nutrition Examination Survey, 1988–1994 , 1998, Diabetes Care.

[32]  S. Akira,et al.  Defective adipocyte differentiation in mice lacking the C/EBPβ and/or C/EBPδ gene , 1997 .

[33]  J. Lovejoy,et al.  Abdominal fat distribution and metabolic risk factors: effects of race. , 1996, Metabolism: clinical and experimental.

[34]  J. Stephens,et al.  The Expression and Regulation of STATs during 3T3-L1 Adipocyte Differentiation (*) , 1996, The Journal of Biological Chemistry.

[35]  R. Harris,et al.  Early and late stimulation of ob mRNA expression in meal-fed and overfed rats. , 1996, The Journal of clinical investigation.

[36]  E. Ravussin,et al.  A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM , 1995, Diabetologia.

[37]  S. McKnight,et al.  Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. , 1995, Genes & development.

[38]  J. Flier,et al.  The adipocyte: Storage depot or node on the energy information superhighway? , 1995, Cell.

[39]  B. Spiegelman,et al.  Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor , 1994, Cell.

[40]  B. Spiegelman,et al.  mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. , 1994, Genes & development.

[41]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[42]  H. Koistinen,et al.  Insulin action on expression of novel adipose genes in healthy and type 2 diabetic subjects. , 2004, Obesity research.

[43]  S. Kwak,et al.  NF-kappaB is involved in the TNF-alpha induced inhibition of the differentiation of 3T3-L1 cells by reducing PPARgamma expression. , 2003, Experimental & molecular medicine.

[44]  T. Willson,et al.  Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues. , 2001, Endocrinology.

[45]  B. Spiegelman,et al.  Molecular regulation of adipogenesis. , 2000, Annual review of cell and developmental biology.

[46]  B. Spiegelman,et al.  ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[47]  S. Akira,et al.  Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. , 1997, The EMBO journal.

[48]  B. Spiegelman,et al.  Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. , 1994, Cell.

[49]  G. Shulman,et al.  On Diabetes: Insulin Resistance Cellular Mechanisms of Insulin Resistance , 2022 .