Estimating the Breast Surface Using UWB Microwave Monostatic Backscatter Measurements

This paper presents an algorithm for estimating the location of the breast surface from scattered ultrawideband (UWB) microwave signals recorded across an antenna array. Knowing the location of the breast surface can improve imaging performance if incorporated as a priori information into recently proposed microwave imaging algorithms. These techniques transmit low-power microwaves into the breast using an antenna array, which in turn measures the scattered microwave signals for the purpose of detecting anomalies or changes in the dielectric properties of breast tissue. Our proposed surface identification algorithm consists of three procedures, the first of which estimates points on the breast surface given channels of measured microwave backscatter data. The second procedure applies interpolation and extrapolation to these points to generate points that are approximately uniformly distributed over the breast surface, while the third procedure uses these points to generate a 3-D estimated breast surface. Numerical as well as experimental tests indicate that the maximum absolute error in the estimated surface generated by the algorithm is on the order of several millimeters. An error analysis conducted for a basic microwave radar imaging algorithm (least-squares narrowband beamforming) indicates that this level of error is acceptable. A key advantage of the algorithm is that it uses the same measured signals that are used for UWB microwave imaging, thereby minimizing patient scan time and avoiding the need for additional hardware.

[1]  Paul M. Meaney,et al.  Microwave imaging for neoadjuvant chemotherapy monitoring , 2006, 2006 First European Conference on Antennas and Propagation.

[2]  김덕영 [신간안내] Computational Electrodynamics (the finite difference time - domain method) , 2001 .

[3]  E. Madsen,et al.  Tissue-mimicking phantom materials for narrowband and ultrawideband microwave applications , 2005, Physics in medicine and biology.

[4]  M. Lindstrom,et al.  A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries , 2007, Physics in medicine and biology.

[5]  Stuchly,et al.  Dielectric properties of breast carcinoma and the surrounding tissues , 1988, IEEE Transactions on Biomedical Engineering.

[6]  M. Stuchly,et al.  Experimental feasibility study of confocal microwave imaging for breast tumor detection , 2003 .

[7]  S. K. Davis,et al.  MICROWAVE IMAGING VIA SPACE-TIME BEAMFORMING FOR EARLY DETECTION OF BREAST CANCER: BEAMFORMER DESIGN IN THE FREQUENCY DOMAIN , 2003 .

[8]  P L Carson,et al.  Anthropomorphic breast phantoms for assessing ultrasonic imaging system performance and for training ultrasonographers: Part II , 1982, Journal of clinical ultrasound : JCU.

[9]  D. W. van der Weide,et al.  Microwave imaging via space-time beamforming: experimental investigation of tumor detection in multilayer breast phantoms , 2004, IEEE Transactions on Microwave Theory and Techniques.

[10]  Allen Taflove,et al.  Computational Electrodynamics the Finite-Difference Time-Domain Method , 1995 .

[11]  Barry D. Van Veen,et al.  Ultrawideband microwave breast cancer detection: a detection-theoretic approach using the generalized likelihood ratio test , 2005, IEEE Transactions on Biomedical Engineering.

[12]  A. Taflove,et al.  Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: fixed-focus and antenna-array sensors , 1998, IEEE Transactions on Biomedical Engineering.

[13]  Elise C. Fear,et al.  Microwave detection of breast cancer , 2000 .

[14]  S.C. Hagness,et al.  A confocal microwave imaging algorithm for breast cancer detection , 2001, IEEE Microwave and Wireless Components Letters.

[15]  D. Land,et al.  Dielectric properties of female human breast tissue measured in vitro at 3.2 GHz. , 1992, Physics in medicine and biology.

[16]  Barry D. Van Veen,et al.  Breast Tumor Characterization Based on Ultrawideband Microwave Backscatter , 2008, IEEE Transactions on Biomedical Engineering.

[17]  Takuya Sakamoto,et al.  A Target Shape Estimation Algorithm for Pulse Radar Systems Based on Boundary Scattering Transform , 2004 .

[18]  Paul M. Meaney,et al.  Conformal microwave imaging for breast cancer detection , 2003 .

[19]  Xu Li,et al.  Microwave imaging via space-time beamforming for early detection of breast cancer , 2002, 2002 IEEE International Conference on Acoustics, Speech, and Signal Processing.

[20]  X. Li,et al.  Confocal microwave imaging for breast cancer detection: localization of tumors in three dimensions , 2002, IEEE Transactions on Biomedical Engineering.

[21]  S. S. Chaudhary,et al.  Dielectric properties of normal & malignant human breast tissues at radiowave & microwave frequencies. , 1984, Indian journal of biochemistry & biophysics.

[22]  G. Wahba Spline models for observational data , 1990 .

[23]  A. Bulyshev,et al.  Three-dimensional vector microwave tomography: theory and computational experiments , 2004 .

[24]  Ian J Craddock,et al.  Numerical investigation of breast tumour detection using multi-static radar , 2003 .

[25]  M. Lindstrom,et al.  A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries , 2007, Physics in medicine and biology.

[26]  Shireen D. Geimer,et al.  Microwave image reconstruction from 3-D fields coupled to 2-D parameter estimation , 2004, IEEE Transactions on Medical Imaging.

[27]  B.D. Van Veen,et al.  An overview of ultra-wideband microwave imaging via space-time beamforming for early-stage breast-cancer detection , 2005, IEEE Antennas and Propagation Magazine.

[28]  P. Kosmas,et al.  Time reversal with the FDTD method for microwave breast cancer detection , 2005, IEEE Transactions on Microwave Theory and Techniques.

[29]  S.C. Hagness,et al.  Numerical and experimental investigation of an ultrawideband ridged pyramidal horn antenna with curved launching plane for pulse radiation , 2003, IEEE Antennas and Wireless Propagation Letters.

[30]  B.D. Van Veen,et al.  Estimation of the Frequency-Dependent Average Dielectric Properties of Breast Tissue Using a Time-Domain Inverse Scattering Technique , 2006, IEEE Transactions on Antennas and Propagation.

[31]  Qing Huo Liu,et al.  Three-dimensional nonlinear image reconstruction for microwave biomedical imaging , 2004, IEEE Transactions on Biomedical Engineering.

[32]  W. Joines,et al.  The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz. , 1994, Medical physics.

[33]  Paul M. Meaney,et al.  A clinical prototype for active microwave imaging of the breast , 2000 .

[34]  P. M. Berg,et al.  Imaging of biomedical data using a multiplicative regularized contrast source inversion method , 2002 .

[35]  S. Kidera,et al.  A high-resolution 3-D imaging algorithm with linear array antennas for UWB pulse radar systems , 2006, 2006 IEEE Antennas and Propagation Society International Symposium.