Automated polyp segmentation for colonoscopy images: A method based on convolutional neural networks and ensemble learning.

PURPOSE To automatically and efficiently segment the lesion area of the colonoscopy polyp image, a polyp segmentation method has been presented. METHODS An ensemble model of pretrained convolutional neural networks was proposed, using Unet-VGG, SegNet-VGG, and PSPNet. Firstly, the Unet-VGG is obtained by the first 10 layers of VGG16 as the contraction path of the left half of the Unet. Then, the SegNet-VGG is acquired by fine-tuned transfer learning VGG16, using the first 13 layers of VGG16 as the encoder of the SegNet and combined the original decoder of the SegNet. By adjusting the input size of the Unet-VGG, SegNet-VGG, and PSPNet, the preprocessed data can be correctly fed to the three network models. The three models are used as the basic trainer to train and segment the datasets. Based on the ensemble learning algorithm, the weight voting method is used to ensemble the segmentation results corresponding to single basic trainer. RESULTS Both IoU and DICE similarity score were used to evaluate the segmentation quality for cvc300 with 300 images, CVC-ClinicDB with 612 images, and ETIS-LaribPolypDB with 196 images. From the experimental results, the IoU and DICE obtained by the proposed method for the cvc300 datasets can reach up to 96.16% and 98.04%, respectively, the IoU and DICE for the CVC-ClinicDB datasets can reach up to 96.66% and 98.30%, respectively, whereas the IoU and DICE for the ETIS-LaribPolypDB datasets can reach up to 96.95% and 98.45%, respectively. Evaluation of the IoU and DICE in our methods shows higher accuracy than previous methods. CONCLUSIONS The experimental results show that the proposed method improved correspondingly in IoU and DICE compared to a single basic trainer. The range of improvement is 1.98%-6.38%. The proposed ensemble learning succeeds in automatic polyp segmentation, which potentially helps to establish more polyp datasets.

[1]  Omid Haji Maghsoudi,et al.  Superpixels based marker tracking vs. hue thresholding in rodent biomechanics application , 2017, 2017 51st Asilomar Conference on Signals, Systems, and Computers.

[2]  Iasonas Kokkinos,et al.  DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs , 2016, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[3]  Dhiya Al-Jumeily,et al.  Boundary Delineation of MRI Images for Lumbar Spinal Stenosis Detection Through Semantic Segmentation Using Deep Neural Networks , 2019, IEEE Access.

[4]  Cha Zhang,et al.  Ensemble Machine Learning , 2012 .

[5]  Yuji Iwahori,et al.  Active contour segmentation of polyps in capsule endoscopic images , 2018, 2018 International Conference on Signals and Systems (ICSigSys).

[6]  Antonio M. López,et al.  A Benchmark for Endoluminal Scene Segmentation of Colonoscopy Images , 2016, Journal of healthcare engineering.

[7]  Alejandro F. Frangi,et al.  Bayesian Polytrees With Learned Deep Features for Multi-Class Cell Segmentation , 2019, IEEE Transactions on Image Processing.

[8]  Zhiming Luo,et al.  A Global and Local Enhanced Residual U-Net for Accurate Retinal Vessel Segmentation , 2019, IEEE/ACM Transactions on Computational Biology and Bioinformatics.

[9]  Sang-Woong Lee,et al.  Colorectal Segmentation Using Multiple Encoder-Decoder Network in Colonoscopy Images , 2018, 2018 IEEE First International Conference on Artificial Intelligence and Knowledge Engineering (AIKE).

[10]  Fernando Vilariño,et al.  Towards automatic polyp detection with a polyp appearance model , 2012, Pattern Recognit..

[11]  Akshay Madrosiya,et al.  Colorectal polyp segmentation using front propagation on surfaces guided by shape , 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[12]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[13]  Tianfu Wang,et al.  Colorectal polyp segmentation using a fully convolutional neural network , 2017, 2017 10th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI).

[14]  Roberto Cipolla,et al.  SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation , 2015, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[15]  Prasanta Kumar Ghosh,et al.  An Improved Air Tissue Boundary Segmentation Technique for Real Time Magnetic Resonance Imaging Video Using Segnet , 2019, ICASSP 2019 - 2019 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP).

[16]  Zhipeng Ge,et al.  ROAD EXTRACTION FROM REMOTE SENSING IMAGES BY MULTIPLE FEATURE PYRAMID NETWORK , 2018, IGARSS 2018 - 2018 IEEE International Geoscience and Remote Sensing Symposium.

[17]  Fernando Vilariño,et al.  WM-DOVA maps for accurate polyp highlighting in colonoscopy: Validation vs. saliency maps from physicians , 2015, Comput. Medical Imaging Graph..

[18]  Mengxi Xu,et al.  Change Detection Based on the Combination of Improved SegNet Neural Network and Morphology , 2018, 2018 IEEE 3rd International Conference on Image, Vision and Computing (ICIVC).

[19]  Surabhi Bhargava,et al.  A Dataset and a Technique for Generalized Nuclear Segmentation for Computational Pathology , 2017, IEEE Transactions on Medical Imaging.

[20]  Ilangko Balasingham,et al.  Automatic Colon Polyp Detection Using Region Based Deep CNN and Post Learning Approaches , 2018, IEEE Access.

[21]  Yuji Iwahori,et al.  Automatic Segmentation of Polyps in Endoscopic Image Using Level-Set Formulation , 2018, 2018 International Conference on Wireless Communications, Signal Processing and Networking (WiSPNET).

[22]  L. R. Dice Measures of the Amount of Ecologic Association Between Species , 1945 .

[23]  Trevor Darrell,et al.  Fully Convolutional Networks for Semantic Segmentation , 2017, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[24]  Max Q.-H. Meng,et al.  Automatic Polyp Detection via a Novel Unified Bottom-Up and Top-Down Saliency Approach , 2018, IEEE Journal of Biomedical and Health Informatics.

[25]  Ilangko Balasingham,et al.  Date of publication xxxx 00, 0000, date of current version xxxx 00, 0000 , 2019 .

[26]  Xiaogang Wang,et al.  Pyramid Scene Parsing Network , 2016, 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[27]  Raymond Y. K. Lau,et al.  Road Detection and Centerline Extraction Via Deep Recurrent Convolutional Neural Network U-Net , 2019, IEEE Transactions on Geoscience and Remote Sensing.

[28]  Ryusuke Miyamoto,et al.  Accurate Fashion Style Estimation with a Novel Training Set and Removal of Unnecessary Pixels , 2019, 2019 IEEE International Symposium on Circuits and Systems (ISCAS).

[29]  Yujie Li,et al.  NAS-Unet: Neural Architecture Search for Medical Image Segmentation , 2019, IEEE Access.

[30]  Chi-Wing Fu,et al.  H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation From CT Volumes , 2018, IEEE Transactions on Medical Imaging.

[31]  Jiangye Yuan,et al.  Building Extraction at Scale Using Convolutional Neural Network: Mapping of the United States , 2018, IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing.

[32]  Wei-Min Liu,et al.  Semantic Segmentation of Colorectal Polyps with DeepLab and LSTM Networks , 2018, 2018 IEEE International Conference on Consumer Electronics-Taiwan (ICCE-TW).

[33]  Pulkit Kumar,et al.  U-Segnet: Fully Convolutional Neural Network Based Automated Brain Tissue Segmentation Tool , 2018, 2018 25th IEEE International Conference on Image Processing (ICIP).

[34]  Ebrahim Nasr-Esfahani,et al.  Polyp Segmentation in Colonoscopy Images Using Fully Convolutional Network , 2018, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[35]  Md. Kamrul Hasan,et al.  Automatic Traffic Sign Detection and Recognition Using SegU-Net and a Modified Tversky Loss Function With L1-Constraint , 2020, IEEE Transactions on Intelligent Transportation Systems.

[36]  Michael Kampffmeyer,et al.  UNCERTAINTY MODELING AND INTERPRETABILITY IN CONVOLUTIONAL NEURAL NETWORKS FOR POLYP SEGMENTATION , 2018, 2018 IEEE 28th International Workshop on Machine Learning for Signal Processing (MLSP).

[37]  Daniel Sierra-Sosa,et al.  Automatic colon polyp detection using Convolutional encoder-decoder model , 2017, 2017 IEEE International Symposium on Signal Processing and Information Technology (ISSPIT).

[38]  Jun Li,et al.  Segnet-based gland segmentation from colon cancer histology images , 2018, 2018 33rd Youth Academic Annual Conference of Chinese Association of Automation (YAC).

[39]  Haolun Wu,et al.  Pixel Level Image Encryption Based on Semantic Segmentation , 2018, 2018 International Conference on Control, Artificial Intelligence, Robotics & Optimization (ICCAIRO).

[40]  Jian Yang,et al.  Combining ElasticFusion with PSPNet for RGB-D Based Indoor Semantic Mapping , 2018, 2018 Chinese Automation Congress (CAC).

[41]  Seunghoon Hong,et al.  Learning Deconvolution Network for Semantic Segmentation , 2015, 2015 IEEE International Conference on Computer Vision (ICCV).

[42]  Yao Lu,et al.  RIC-Unet: An Improved Neural Network Based on Unet for Nuclei Segmentation in Histology Images , 2019, IEEE Access.

[43]  Lianru Gao,et al.  CNN-based Large Scale Landsat Image Classification , 2018, 2018 Asia-Pacific Signal and Information Processing Association Annual Summit and Conference (APSIPA ASC).

[44]  Manfred K. Warmuth,et al.  The Weighted Majority Algorithm , 1994, Inf. Comput..