Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog
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Paul A. Khavari | M. Scott | P. Khavari | Matthew P. Scott | A. Oro | Hongran Fan | Anthony E. Oro | H. Fan
[1] Andrew P. McMahon,et al. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity , 1993, Cell.
[2] P. Ingham,et al. smoothened encodes a receptor-like serpentine protein required for hedgehog signalling , 1996, Nature.
[3] Stanley J. Miller,et al. Biology of basal cell carcinoma (Part II). , 1991, Journal of the American Academy of Dermatology.
[4] E. Lane,et al. Antibody markers of basal cells in complex epithelia. , 1990, Journal of cell science.
[5] R. Tompkins,et al. Evaluation of human skin reconstituted from composite grafts of cultured keratinocytes and human acellular dermis transplanted to athymic mice. , 1996, The Journal of investigative dermatology.
[6] Andrew P. McMahon,et al. The world according to bedgebog , 1997 .
[7] P. Ingham. Signalling by hedgehog family proteins in Drosophila and vertebrate development. , 1995, Current opinion in genetics & development.
[8] M. H. Hardy,et al. The secret life of the hair follicle. , 1992, Trends in genetics : TIG.
[9] M. Noll,et al. The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal , 1996, Cell.
[10] K. Resing,et al. Characterization of two monoclonal antibodies to human epidermal keratohyalin: reactivity with filaggrin and related proteins. , 1987, The Journal of investigative dermatology.
[11] R. Burgeson,et al. Basement membrane proteins kalinin and nicein are structurally and immunologically identical. , 1993, Laboratory investigation; a journal of technical methods and pathology.
[12] T. Tabata,et al. Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs , 1994, Cell.
[13] R. Myers,et al. Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome , 1996, Science.
[14] Paul A. Khavari,et al. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription , 1993, Nature.
[15] L. Trusolino,et al. Expression and topography of integrins and basement membrane proteins in epidermal carcinomas: Basal but not squamous cell carcinomas display loss of α6β4 and BM-600/nicein , 1993 .
[16] P. Ingham,et al. Regulation of wingless transcription in the Drosophila embryo. , 1993, Development.
[17] G. Struhl,et al. Dual Roles for Patched in Sequestering and Transducing Hedgehog , 1996, Cell.
[18] M. Rijn,et al. bcl-2 expression in primary malignancies of the skin. , 1995, Archives of dermatology.
[19] G. Pinkus,et al. Involucrin expression in normal and neoplastic human skin: a marker for keratinocyte differentiation. , 1984, The Journal of investigative dermatology.
[20] A. McMahon,et al. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. , 1995, Developmental biology.
[21] B. Koller,et al. A murine model of cystic fibrosis. , 1995, American journal of respiratory and critical care medicine.
[22] N. Copeland,et al. Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog. , 1995, Genomics.
[23] P. Khavari,et al. Corrective gene transfer in the human skin disorder lamellar ichthyosis , 1996, Nature Medicine.
[24] Walter F. Lever,et al. Histopathology of the Skin , 1990 .
[25] G. Nolan,et al. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. , 1996, Human gene therapy.
[26] J. Troy,et al. A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180. , 1993, The Journal of clinical investigation.
[27] Michael Dean,et al. Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome , 1996, Cell.
[28] G. Nolan,et al. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. , 1996, Human gene therapy.
[29] M. Scott,et al. Basal cell carcinomas in mice overexpressing sonic hedgehog. , 1997, Science.
[30] Michael Dean,et al. Is human patched the gatekeeper of common skin cancers? , 1996, Nature Genetics.
[31] T. Friedmann,et al. Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[32] C. Nüsslein-Volhard,et al. Mutations affecting segment number and polarity in Drosophila , 1980, Nature.
[33] A. McMahon,et al. Hedgehogs in the clinic , 1996, Nature Medicine.
[34] H. Green,et al. Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is , 1975, Cell.
[35] A. McMahon,et al. Proteolytic processing yields two secreted forms of sonic hedgehog , 1995, Molecular and cellular biology.
[36] C. Tabin,et al. Sonic hedgehog mediates the polarizing activity of the ZPA , 1993, Cell.
[37] Stephen C. Ekker,et al. The product of hedgehog autoproteolytic cleavage active in local and long-range signalling , 1995, Nature.
[38] C. Helms,et al. Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly , 1996, Nature Genetics.
[39] H. Green,et al. Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma , 1975, Cell.
[40] A. Bradley,et al. High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC , 1995, Nature.
[41] M. Scott,et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog , 1996, Nature.
[42] Arbeit Jm. Transgenic models of epidermal neoplasia and multistage carcinogenesis , 1996 .
[43] M. Neuburg,et al. Expression pattern of the bullous pemphigoid‐180 antigen in normal and neoplastic epithelia , 1995, The British journal of dermatology.
[44] S. Scherer,et al. Mutations in the human Sonic Hedgehog gene cause holoprosencephaly , 1996, Nature Genetics.
[45] P. Beachy,et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function , 1996, Nature.