Is Gender a Risk Factor for Adverse Drug Reactions?

[1]  B. Lund,et al.  Olanzapine Plasma Concentrations and Clinical Response: Acute Phase Results of the North American Olanzapine Trial , 2001, Journal of clinical psychopharmacology.

[2]  T. Simon,et al.  Sex Differences in the Prognosis of Congestive Heart Failure: Results From the Cardiac Insufficiency Bisoprolol Study (CIBIS II) , 2001, Circulation.

[3]  G. Tollefson,et al.  No gender differences in placebo responses of patients with major depressive disorder , 2001, Biological Psychiatry.

[4]  L. Wilhelmsen,et al.  Optimal risk factors in the population: prognosis, prevalence, and secular trends; data from Göteborg population studies. , 2001, European heart journal.

[5]  A. Ströhle Increased response to a putative panicogenic nocebo administration in female patients with panic disorder. , 2000, Journal of psychiatric research.

[6]  D M Roden,et al.  A common polymorphism associated with antibiotic-induced cardiac arrhythmia. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[7]  J. Reiffel,et al.  Effects of Aging and Gender on QT Dispersion in an Overtly Healthy Population , 2000 .

[8]  S. Priori,et al.  Evidence for a Cardiac Ion Channel Mutation Underlying Drug‐Induced QT Prolongation and Life‐Threatening Arrhythmias , 2000, Journal of cardiovascular electrophysiology.

[9]  Hajnalka Orvos,et al.  Gender-Related Heart Rate Differences in Human Neonates , 2000, Pediatric Research.

[10]  R. Woosley,et al.  Mechanism of cardiotoxicity of halofantrine , 2000, Clinical pharmacology and therapeutics.

[11]  D. Flockhart,et al.  Greater quinidine‐induced QTc interval prolongation in women , 2000, Clinical pharmacology and therapeutics.

[12]  F. Follath,et al.  Epidemiology of drug exposure and adverse drug reactions in two swiss departments of internal medicine. , 2000, British journal of clinical pharmacology.

[13]  P. Hjemdahl,et al.  Gender-related differences in response to placebo in benzodiazepine withdrawal: a single-blind pilot study , 2000, Psychopharmacology.

[14]  Michael F. Wilson,et al.  Gender‐related effects on metoprolol pharmacokinetics and pharmacodynamics in healthy volunteers , 1999, Clinical pharmacology and therapeutics.

[15]  L Guize,et al.  Associations between heart rate and other risk factors in a large French population. , 1999, Journal of hypertension.

[16]  S. Viskin Long QT syndromes and torsade de pointes , 1999, The Lancet.

[17]  S. Datta,et al.  Beta-estradiol acutely potentiates the depression of cardiac excitability by lidocaine and bupivacaine. , 1999, Journal of cardiovascular pharmacology.

[18]  A. Katchman,et al.  Female gender is a risk factor for torsades de pointes in an in vitro animal model. , 1999, Journal of cardiovascular pharmacology.

[19]  M. Keating,et al.  MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia , 1999, Cell.

[20]  Wen-Chung Yu,et al.  Effects of 17β‐Estradiol on Tachycardia‐Induced Changes of Atrial Refractoriness and Cisapride‐Induced Ventricular Arrhythmia , 1999, Journal of cardiovascular electrophysiology.

[21]  S. Priori,et al.  Low penetrance in the long-QT syndrome: clinical impact. , 1999, Circulation.

[22]  M. Lehmann,et al.  JTc prolongation with d,l-sotalol in women versus men. , 1999, The American journal of cardiology.

[23]  R. Hauer,et al.  Genetic and molecular basis of cardiac arrhythmias : Impact on clinical management , 1999 .

[24]  A. Katchman,et al.  The antiestrogen tamoxifen blocks the delayed rectifier potassium current, IKr, in rabbit ventricular myocytes. , 1998, The Journal of pharmacology and experimental therapeutics.

[25]  B. Knollmann,et al.  Cardiac actions of erythromycin: influence of female sex. , 1998, JAMA.

[26]  S. Knowles,et al.  Gender Differences in Adverse Drug Reactions , 1998, Journal of clinical pharmacology.

[27]  A. Kadish,et al.  Effects of hormone replacement therapy on QT interval. , 1998, The American journal of cardiology.

[28]  D. Roden Mechanisms and management of proarrhythmia. , 1998, The American journal of cardiology.

[29]  M. Lazdunski,et al.  Involvement of IsK-associated K+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome. , 1998, Circulation research.

[30]  S. Priori,et al.  Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome: findings from the International LQTS Registry. , 1998, Circulation.

[31]  A. Kadish,et al.  Effects of Gender on Cardiac Arrhythmias , 1998, Journal of cardiovascular electrophysiology.

[32]  R. Woosley,et al.  Female gender as a risk factor for drug-induced cardiac arrhythmias: evaluation of clinical and experimental evidence. , 1998, Journal of women's health.

[33]  M. Rosen,et al.  Effects of gonadal steroids on ventricular repolarization and on the response to E4031. , 1998, The Journal of pharmacology and experimental therapeutics.

[34]  D. Roden Taking the “Idio” out of “Idiosyncratic”: Predicting Torsades de Pointes , 1998, Pacing and clinical electrophysiology : PACE.

[35]  G. Mann,et al.  Environmental estrogenic pollutants induce acute vascular relaxation by inhibiting L‐type Ca2+ channels in smooth muscle cells , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[36]  M. Morad,et al.  Gender difference in the cycle length-dependent QT and potassium currents in rabbits. , 1998, The Journal of pharmacology and experimental therapeutics.

[37]  A. Camm,et al.  Mortality in the Survival With ORal D-sotalol (SWORD) trial: why did patients die? , 1998, The American journal of cardiology.

[38]  Y. P. Adams,et al.  MECHANISMS AND MANAGEMENT , 1998 .

[39]  Edmeads Jg,et al.  Tolerability Profile of Zolmitriptan (Zomig™; 311C90), a Novel Dual Central and Peripherally Acting 5HT1B/1D Agonist: International Clinical Experience Based on > 3000 Subjects Treated with Zolmitriptan , 1997 .

[40]  A. Krahn,et al.  Hysteresis of the RT interval with exercise: a new marker for the long-QT syndrome? , 1997, Circulation.

[41]  P. Coumel,et al.  Physiology of QT Interval Dynamicity , 1997 .

[42]  U. Heiden,et al.  Magnesium abolishes inadequate kinetics of frequency adaptation of the Q-aT interval in the presence of sotalol. , 1997, Cardiovascular research.

[43]  P. Schwartz,et al.  Gender and the relationship between ventricular repolarization and cardiac cycle length during 24-h Holter recordings. , 1997, European heart journal.

[44]  A. Moss,et al.  Age-gender influence on the rate-corrected QT interval and the QT-heart rate relation in families with genotypically characterized long QT syndrome. , 1997, Journal of the American College of Cardiology.

[45]  P. Kligfield,et al.  QT interval-heart rate relation during exercise in normal men and women: definition by linear regression analysis. , 1996, Journal of the American College of Cardiology.

[46]  M. Lehmann,et al.  Sex difference in risk of torsade de pointes with d,l-sotalol. , 1996, Circulation.

[47]  H. Hirao,et al.  Frequency-dependent electrophysiologic properties of ventricular repolarization in patients with congenital long QT syndrome. , 1996, Journal of the American College of Cardiology.

[48]  C. Funck-Brentano,et al.  Influence of dofetilide on QT-interval duration and dispersion at various heart rates during exercise in humans. , 1996, Circulation.

[49]  R. Glazer,et al.  Sex hormones prolong the QT interval and downregulate potassium channel expression in the rabbit heart. , 1996, Circulation.

[50]  R. Chaisson,et al.  Adverse events from drug therapy for human immunodeficiency virus disease. , 1996, The American journal of medicine.

[51]  J. Sowers,et al.  Tamoxifen (estrogen antagonist) inhibits voltage-gated calcium current and contractility in vascular smooth muscle from rats. , 1996, The Journal of pharmacology and experimental therapeutics.

[52]  P. Sarrel,et al.  Cyclical variation in paroxysmal supraventricular tachycardia in women , 1996, The Lancet.

[53]  V. Fuster,et al.  Management of patients with atrial fibrillation. A Statement for Healthcare Professionals. From the Subcommittee on Electrocardiography and Electrophysiology, American Heart Association. , 1996, Circulation.

[54]  D. Roden,et al.  Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence. , 1996, Circulation.

[55]  Carlo Napolitano,et al.  Erratum: Long QT syndrome patients with mutations on the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate: Implications for gene-specific therapy (Circulation (1995) 92 (3381-3386)) , 1996 .

[56]  S. Priori,et al.  Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. , 1995, Circulation.

[57]  N. Holford,et al.  Moclobemide: relationships between dose, drug concentration in plasma, and occurrence of adverse events. , 1995, Journal of clinical psychopharmacology.

[58]  P. Schwartz,et al.  Are gender differences in QTc present at birth? MISNES Investigators. Multicenter Italian Study on Neonatal Electrocardiography and Sudden Infant Death Syndrome. , 1995, The American journal of cardiology.

[59]  R. Cannon,et al.  Effect of combined 17 beta-estradiol and vitamin E on low-density lipoprotein oxidation in postmenopausal women. , 1995, The American journal of cardiology.

[60]  D. D. Bono,et al.  QT dispersion and mortality after myocardial infarction , 1995, The Lancet.

[61]  M. Drici,et al.  Influence of the behaviour pattern on the nocebo response of healthy volunteers. , 1995, British journal of clinical pharmacology.

[62]  J. Schwartz,et al.  Aging of women alters S‐verapamil pharmacokinetics and pharmacodynamics , 1994, Clinical pharmacology and therapeutics.

[63]  P. Ward,et al.  Effect of age and gender on tirilazad pharmacokinetics in humans , 1994, Clinical pharmacology and therapy.

[64]  P Jaillon,et al.  Rate-corrected QT interval: techniques and limitations. , 1993, The American journal of cardiology.

[65]  G Cheymol,et al.  Clinical Pharmacokinetics of Drugs in Obesity , 1993, Clinical pharmacokinetics.

[66]  M. Lehmann,et al.  Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. , 1993, JAMA.

[67]  D. Wyse,et al.  Precordial QT Interval Dispersion as a Marker of Torsade de Pointes: Disparate Effects of Class Ta Antiarrhythmic Drugs and Amiodarone , 1992, Circulation.

[68]  R. Prineas,et al.  Sex differences in the evolution of the electrocardiographic QT interval with age. , 1992, The Canadian journal of cardiology.

[69]  S. Datta,et al.  Effects of progesterone on the cardiac electrophysiologic action of bupivacaine and lidocaine. , 1992, Anesthesiology.

[70]  K. Hashiba Sex Differences in Phenotypic Manifestation and Gene Transmission in the Romano‐Ward Syndrome , 1992, Annals of the New York Academy of Sciences.

[71]  G. Vincent,et al.  Effects of exercise on heart rate, QT, QTc and QT/QS2 in the Romano-Ward inherited long QT syndrome. , 1991, The American journal of cardiology.

[72]  Graham A. Colditz,et al.  Menopause and Heart Disease , 1990 .

[73]  J. Mccomb,et al.  QT dispersion: an indication of arrhythmia risk in patients with long QT intervals. , 1990, British heart journal.

[74]  J. Trimmer,et al.  Estrogen induction of a small, putative K+ channel mRNA in rat uterus , 1990, Neuron.

[75]  A J Moss,et al.  Electrocardiographic quantitation of ventricular repolarization. , 1989, Circulation.

[76]  D. Greenblatt,et al.  Imipramine disposition in users of oral contraceptive steroids , 1984, Clinical pharmacology and therapeutics.

[77]  J. Pasqualini Receptors and mechanism of action of steroid hormones , 1978 .

[78]  N. Goldschlager,et al.  A Clinical and Hemodynamic Study , 1973 .

[79]  G. Cramér Early and late results of conversion of atrial fibrillation with quinidine. A clinical and hemodynamic study. , 1968, Acta medica Scandinavica. Supplementum.

[80]  F Dessertenne,et al.  [Ventricular tachycardia with 2 variable opposing foci]. , 1966, Archives des maladies du coeur et des vaisseaux.

[81]  R. Shipley,et al.  The four-lead electrocardiogram in two hundred normal men and women , 1936 .

[82]  H. Bazett,et al.  AN ANALYSIS OF THE TIME‐RELATIONS OF ELECTROCARDIOGRAMS. , 1997 .