Improved method for cardiac output determination in man using ultrasound Doppler technique

An existing ultrasound Doppler method for measuring cardiac output has been improved and refined, partly by locating the sampling volume higher up in the aorta while still using the aortic ring size as the effective transverse flow area. The basis for using this technique is the approximately rectangular systolic velocity profile in the aortic orifice in physiologically and anatomically normal subjects, and the fact that this profile velocity is conserved as the maximum velocity in the ascending aorta for some 3 to 4 cm above the valves. This higher location of the sampling volume improves Doppler signal quality, and does not reduce the accuracy of the method, as can be confirmed in each experimental subject. Together with automatic computer-based online signal analysis, the technique employed enables us to make continuous long-term beat-to-beat measurements of cardiac output in subjects without aortic valve disease or grossly deforming disease of the aortic root.

[1]  G. Dobb,et al.  Non-invasive methods of measuring cardiac output , 2004, Intensive Care Medicine.

[2]  Hunter Rouse,et al.  Fluid Mechanics for Hydraulic Engineers , 1961 .

[3]  G. Uijen,et al.  Determination of cardiac output by single gated pulsed Doppler echocardiography. , 1988, International journal of cardiology.

[4]  E. Sonnenblick,et al.  The heart as a suction pump. , 1986, Scientific American.

[5]  H. Ihlen,et al.  Reproducibility of cardiac stroke volume estimated by Doppler echocardiography. , 1987, The American journal of cardiology.

[6]  K. Matre,et al.  Blood velocity distribution in the human ascending aorta. , 1987, Circulation.

[7]  J. Wesche,et al.  Time course and magnitude of blood flow changes in the human quadriceps muscles during and following rhythmic exercise. , 1988, The Journal of physiology.

[8]  L. M. Sheldahl,et al.  Determination of Stroke Volume and Cardiac Output During Exercise: Comparison of Two-Dimensional and Doppler Echocardiography, Fick Oximetry, and Thermodilution , 1987, Circulation.

[9]  P. K. Paulsen.  The hot-film anemometer--a method for blood velocity determination. II. In vivo comparison with the electromagnetic blood flowmeter. , 1980, European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes.

[10]  L. Walløe,et al.  Pulsatile pressure and flow in arterial stenoses simulated in a mathematical model. , 1981, Journal of biomedical engineering.

[11]  S Simonsen,et al.  Determination of cardiac output by Doppler echocardiography. , 1984, British heart journal.

[12]  N. Watanabe,et al.  Improvement of Vthcontrol for GaAs FET's by shallow-channel ion implantation , 1986, IEEE Transactions on Electron Devices.

[13]  P. Peronneau,et al.  Flow in the thoracic aorta. , 1979, Cardiovascular research.

[14]  L. Walløe,et al.  Blood flow in arteries determined transcutaneously by an ultrasonic doppler velocitymeter as compared to electromagnetic measurements on the exposed vesels. , 1980, Acta physiologica Scandinavica.

[15]  M. K. Daniel,et al.  Reproducibility of linear cardiac output measurement by Doppler ultrasound alone. , 1986, British heart journal.

[16]  Max Anliker,et al.  Spatial Velocity Distributions in the Ascending Aorta of Healthy Humans and Cardiac Patients , 1986, IEEE Transactions on Biomedical Engineering.