Changes During Disease Progression Somatic Mutation and Multiple Isotype Transcripts in Early Disease With Analysis of VH Genes in Follicular and Diffuse Lymphoma Shows Ongoing

[1]  R M Zinkernagel,et al.  On immunological memory. , 2000, Annual review of immunology.

[2]  D. Oscier,et al.  Differential rates of somatic hypermutation in V(H) genes among subsets of chronic lymphocytic leukemia defined by chromosomal abnormalities. , 1997, Blood.

[3]  P. Casali,et al.  Molecular characterization of IgA- and/or IgG-switched chronic lymphocytic leukemia B cells. , 1997, Blood.

[4]  C. Chapman,et al.  VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection. , 1996, Blood.

[5]  G. Mead,et al.  Histological transformation of indolent (follicular) lymphoma. , 1996, Annals of oncology : official journal of the European Society for Medical Oncology.

[6]  P. Gregersen,et al.  Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells. , 1996, The Journal of clinical investigation.

[7]  O. Burrone,et al.  IgM-producing chronic lymphocytic leukemia cells undergo immunoglobulin isotype-switching without acquiring somatic mutations. , 1996, The Journal of clinical investigation.

[8]  N. Chiorazzi,et al.  Evidence for progenitors of chronic lymphocytic leukemia B cells that undergo intraclonal differentiation and diversification. , 1996, Blood.

[9]  W. Carroll,et al.  The Absence of Ongoing Immunoglobulin Gene Hypermutation Suggests a Distinct Mechanism for c-myc Mutation in Endemic Burkitt's Lymphoma , 1996, Journal of pediatric hematology/oncology.

[10]  J. Banchereau,et al.  B-chronic lymphocytic leukemias can undergo isotype switching in vivo and can be induced to differentiate and switch in vitro. , 1996, Blood.

[11]  F. Stevenson,et al.  Ig VH gene mutational patterns indicate different tumor cell status in human myeloma and monoclonal gammopathy of undetermined significance. , 1996, Blood.

[12]  H. Stein,et al.  Burkitt's lymphomas express VH genes with a moderate number of antigen-selected somatic mutations. , 1995, The American journal of pathology.

[13]  F. Hsu,et al.  Preferential use of the VH4 Ig gene family by diffuse large-cell lymphoma. , 1995, Blood.

[14]  N. Carter,et al.  A Complete Map of the Human Immunoglobulin VH Locus , 1995, Annals of the New York Academy of Sciences.

[15]  C. Chapman,et al.  Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity. , 1995, Blood.

[16]  D. Oscier,et al.  Splenic lymphoma with villous lymphocytes involves B cells with extensively mutated Ig heavy chain variable region genes. , 1995, Blood.

[17]  R. Fisher.  Treatment of aggressive non‐hodgkin's lymphomas: Lessons from the past 10 years , 1994 .

[18]  H Stein,et al.  A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. , 1994, Blood.

[19]  D. Oscier,et al.  Assessment of the role of clonogenic B lymphocytes in the pathogenesis of multiple myeloma. , 1994, Leukemia.

[20]  T. Logtenberg,et al.  In vivo and in vitro IgE isotype switching in human B lymphocytes: Evidence for a predominantly direct IgM to IgE class switch program , 1994, European journal of immunology.

[21]  K. Oka,et al.  A case with primary gastric lymphoma producing IgM and IgG immunoglobulins. , 1994, Archives of Pathology & Laboratory Medicine.

[22]  P. Isaacson,et al.  Sources of DNA for detecting B cell monoclonality using PCR. , 1994, Journal of clinical pathology.

[23]  N. Carter,et al.  A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q , 1994, Nature Genetics.

[24]  G. Dighiero,et al.  The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire. , 1994, Immunology today.

[25]  G. Winter,et al.  Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines. , 1994, Blood.

[26]  K. Thielemans,et al.  Evidence that the clonogenic cell in multiple myeloma originates from a pre‐switched but somatically mutated B cell , 1994, British journal of haematology.

[27]  R. Hawkins,et al.  Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes , 1994, British journal of haematology.

[28]  Moore,et al.  Variable region gene analysis of an isotype-switched (IgA) variant of chronic lymphocytic leukemia. , 1992, Blood.

[29]  C. Heirman,et al.  Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation. , 1992, Blood.

[30]  C. Berek.  The Development of B Cells and the B‐Cell Repertoire in the Microenvironment of the Germinal Center , 1992, Immunological reviews.

[31]  R. Levy,et al.  Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire. , 1992, Molecular immunology.

[32]  G. Mead,et al.  Intensive weekly combination chemotherapy for patients with intermediate-grade and high-grade non-Hodgkin's lymphoma. , 1991, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[33]  M. Nussenzweig,et al.  Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene , 1991, The Journal of experimental medicine.

[34]  A. Zelenetz,et al.  Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B cell , 1991, The Journal of experimental medicine.

[35]  T. Honjo,et al.  Organization of variable region segments of the human immunoglobulin heavy chain: duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments. , 1990, The EMBO journal.

[36]  I. Maclennan,et al.  Mechanism of antigen-driven selection in germinal centres , 1989, Nature.

[37]  J. Sklar,et al.  Somatic Mutation in Human B‐Cell Tumors , 1987, Immunological reviews.

[38]  F. Stevenson,et al.  The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia , 1981, The Journal of experimental medicine.

[39]  S. Hsu,et al.  Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. , 1981, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[40]  I. Tomlinson,et al.  The human immunoglobulin VH repertoire. , 1995, Immunology today.

[41]  P. Leder,et al.  Molecular mechanism for immunoglobulin double-isotype expression. , 1989, Cold Spring Harbor symposia on quantitative biology.

[42]  S. Jagannath,et al.  Effective salvage therapy for lymphoma with cisplatin in combination with high-dose Ara-C and dexamethasone (DHAP). , 1988, Blood.

[43]  A. Bateman,et al.  immunocytochemistry: a study of 80 antibodies , 2022 .