Management of Occupational Exposure to Engineered Nanoparticles Through a Chance-Constrained Nonlinear Programming Approach

Critical environmental and human health concerns are associated with the rapidly growing fields of nanotechnology and manufactured nanomaterials (MNMs). The main risk arises from occupational exposure via chronic inhalation of nanoparticles. This research presents a chance-constrained nonlinear programming (CCNLP) optimization approach, which is developed to maximize the nanaomaterial production and minimize the risks of workplace exposure to MNMs. The CCNLP method integrates nonlinear programming (NLP) and chance-constrained programming (CCP), and handles uncertainties associated with both the nanomaterial production and workplace exposure control. The CCNLP method was examined through a single-walled carbon nanotube (SWNT) manufacturing process. The study results provide optimal production strategies and alternatives. It reveal that a high control measure guarantees that environmental health and safety (EHS) standards regulations are met, while a lower control level leads to increased risk of violating EHS regulations. The CCNLP optimization approach is a decision support tool for the optimization of the increasing MNMS manufacturing with workplace safety constraints under uncertainties.

[1]  Craig A. Poland,et al.  Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma , 2010, Particle and Fibre Toxicology.

[2]  M. L. Healy,et al.  Economic assessment of single-walled carbon nanotube processes , 2010 .

[3]  Dynamically coupled 3D pollutant dispersion model for assessing produced water discharges in the Canadian offshore area. , 2013, Environmental science & technology.

[4]  G H Huang,et al.  An inexact chance-constrained programming model for water quality management in Binhai New Area of Tianjin, China. , 2011, The Science of the total environment.

[5]  U. Zuperl,et al.  A hybrid analytical-neural network approach to the determination of optimal cutting conditions , 2004 .

[6]  James C. Benneyan,et al.  Risk Analysis Modeling of Production Costs and Occupational Health Exposure of Single‐Wall Carbon Nanotube Manufacturing , 2008 .

[7]  이수정.  해외산업간호정보 - 미국 산업안전보건연구원(National Institute for Occupational Safety and Health) 소개 , 2009 .

[8]  B. Tripathi,et al.  Interaction of engineered nanoparticles with various components of the environment and possible strategies for their risk assessment. , 2011, Chemosphere.

[9]  P. Baron,et al.  Exposure to Carbon Nanotube Material: Aerosol Release During the Handling of Unrefined Single-Walled Carbon Nanotube Material , 2004, Journal of toxicology and environmental health. Part A.

[10]  Qiang Xu,et al.  Simultaneous mixed-integer dynamic optimization for environmentally benign electroplating , 2011, Comput. Chem. Eng..

[11]  G. Huang,et al.  Simulation-based inexact chance-constrained nonlinear programming for eutrophication management in the Xiangxi Bay of Three Gorges Reservoir. , 2012, Journal of environmental management.

[12]  Lucas Reijnders,et al.  Workplace exposure to nanoparticles and the application of provisional nanoreference values in times of uncertain risks , 2012, Journal of Nanoparticle Research.

[13]  M. Roller,et al.  Carcinogenicity of inhaled nanoparticles , 2009, Inhalation toxicology.

[14]  Ashutosh Kumar,et al.  Engineered ZnO and TiO(2) nanoparticles induce oxidative stress and DNA damage leading to reduced viability of Escherichia coli. , 2011, Free radical biology & medicine.

[15]  Xiaoshan Zhu,et al.  Toxicity and bioaccumulation of TiO2 nanoparticle aggregates in Daphnia magna. , 2010, Chemosphere.

[16]  G. A. Dervakos,et al.  Process optimization for clean manufacturing : Supercritical fluid extraction for B-carotene production , 1996 .

[17]  G. Biskos,et al.  Mini-Symposium: Nanoparticles and Children's Lungs Airborne Engineered Nanoparticles: Potential Risks and Monitoring Challenges for Assessing their Impacts on Children , 2012 .

[18]  Kenneth A. Smith,et al.  Gas-phase catalytic growth of single-walled carbon nanotubes from carbon monoxide , 1999 .

[19]  M. K. Luhandjula.  Fuzzy stochastic linear programming: Survey and future research directions , 2006, Eur. J. Oper. Res..

[20]  A. Lapresta-Fernández,et al.  Nanoecotoxicity effects of engineered silver and gold nanoparticles in aquatic organisms , 2012 .

[21]  Ord,et al.  Nanotechnology White Paper , 2014 .

[22]  Toly Chen,et al.  A fuzzy set approach for evaluating and enhancing the mid-term competitiveness of a semiconductor factory , 2009, Fuzzy Sets Syst..

[23]  Paul Cullinan,et al.  Personal exposures and microenvironment concentrations of PM2.5, VOC, NO2 and CO in Oxford, UK , 2004 .

[24]  Simon Šilih,et al.  Optimization based comparison between composite I beams and composite trusses , 2003 .

[25]  Derk Brouwer,et al.  Exposure to manufactured nanoparticles in different workplaces. , 2010, Toxicology.

[26]  Thomas L. Theis,et al.  Toward Sustainable Nanoproducts , 2008 .

[27]  P. Schulte,et al.  Occupational exposure limits for nanomaterials: state of the art , 2010 .

[28]  A. Maynard,et al.  Airborne Nanostructured Particles and Occupational Health , 2005 .

[29]  M. L. Healy,et al.  Environmental Assessment of Single‐Walled Carbon Nanotube Processes , 2008 .

[30]  Cynna Selvy,et al.  Occupational Safety and Health Administration (OSHA) , 2015 .

[31]  Bengt Fadeel,et al.  Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress. , 2012, Toxicology and applied pharmacology.

[32]  Jyoti K. Parikh,et al.  Carbon emission coefficient of power consumption in India: baseline determination from the demand side , 2005 .

[33]  Weiping Li,et al.  Applied Nonlinear Control , 1991 .

[34]  G. Hutchison,et al.  Nanoparticle interactions with zinc and iron: implications for toxicology and inflammation. , 2007, Toxicology and applied pharmacology.

[35]  S. Yamada.  [The ten leading work-related diseases and injuries proposed by the National Institute for Occupational Safety and Health (NIOSH)]. , 1986, Journal of UOEH.

[36]  The Nanotechnology Panel of the American Chemistry Council (ACC) is pleased to offer comments on the National Institute for Occupational Safety and Health’s (NIOSH) draft Current Intelligence Bulletin (CIB) Occupational Exposure to Carbon Nanotubes and Nanofibers , 2011 .

[37]  S. Hackenberg,et al.  Cytotoxic, genotoxic and pro-inflammatory effects of zinc oxide nanoparticles in human nasal mucosa cells in vitro. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.

[38]  White,et al.  Are fullerene tubules metallic? , 1992, Physical review letters.

[39]  Christian Micheletti,et al.  Analysis of currently available data for characterising the risk of engineered nanomaterials to the environment and human health--lessons learned from four case studies. , 2011, Environment international.

[40]  Gerhard Kasper,et al.  In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung - A dialog between aerosol science and biology , 2011 .

[41]  D. Kamp,et al.  Asbestos-induced lung diseases: an update. , 2009, Translational research : the journal of laboratory and clinical medicine.

[42]  Baoding Liu,et al.  Uncertain Programming , 1999 .