CDK: cyclin-dependent kinase c-FLIP: cellular FLICE inhibitory protein COX: cyclooxygenase CREB: cAMP response element-binding CSF: colony-stimulating factor DMBA: dimethylbenz[a]anthracene EGCG: epigallocatechin gallate EGF: endothelial growth factor EGFR: epidermal growth factor receptor ERK: extr