Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma: Effects Across a Broad Range of Eosinophil Counts.
暂无分享,去创建一个
[1] D. A. Korevaar,et al. Biomarkers to identify sputum eosinophilia in different adult asthma phenotypes , 2015, European Respiratory Journal.
[2] E. Bateman,et al. Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials. , 2015, The Lancet. Respiratory medicine.
[3] S. Fowler,et al. High blood eosinophil counts predict sputum eosinophilia in patients with severe asthma. , 2015, The Journal of allergy and clinical immunology.
[4] D. Khatry,et al. High blood eosinophil count is a risk factor for future asthma exacerbations in adult persistent asthma. , 2014, The journal of allergy and clinical immunology. In practice.
[5] W. Busse,et al. Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study. , 2014, The Lancet. Respiratory medicine.
[6] Ian D Pavord,et al. Mepolizumab treatment in patients with severe eosinophilic asthma. , 2014, The New England journal of medicine.
[7] E. Rawlins,et al. The best laid schemes of airway repair , 2014, European Respiratory Journal.
[8] C. Janson,et al. Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects. , 2013, The Journal of allergy and clinical immunology.
[9] M. Humbert,et al. Anti-interleukin-5 therapy in severe asthma , 2013, European Respiratory Review.
[10] Ian D Pavord,et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial , 2012, The Lancet.
[11] L. Boulet,et al. Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. , 2011, American journal of respiratory and critical care medicine.
[12] Viswanath Devanarayan,et al. Recommendations for the validation of cell-based assays used for the detection of neutralizing antibody immune responses elicited against biological therapeutics. , 2011, Journal of pharmaceutical and biomedical analysis.
[13] Lakshmi Amaravadi,et al. Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development. , 2011, Journal of immunological methods.
[14] A. Rahman,et al. A novel homogeneous Biotin-digoxigenin based assay for the detection of human anti-therapeutic antibodies in autoimmune serum. , 2010, Journal of immunological methods.
[15] G. Walsh. Reslizumab, a humanized anti-IL-5 mAb for the treatment of eosinophil-mediated inflammatory conditions. , 2009, Current opinion in molecular therapeutics.
[16] Ana Sousa,et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. , 2009, The New England journal of medicine.
[17] Viswanath Devanarayan,et al. Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products. , 2008, Journal of pharmaceutical and biomedical analysis.
[18] Mike Thomas,et al. Cluster analysis and clinical asthma phenotypes. , 2008, American journal of respiratory and critical care medicine.
[19] K. Takatsu,et al. IL-5 and eosinophilia. , 2008, Current opinion in immunology.
[20] S. Wenzel,et al. Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. , 2004, The Journal of allergy and clinical immunology.
[21] D. Postma,et al. Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. , 2003, American journal of respiratory and critical care medicine.
[22] R. Djukanović,et al. The relationship between airways inflammation and asthma severity. , 2000, American journal of respiratory and critical care medicine.
[23] R. Egan,et al. Effect of Sch 55700, a Humanized Monoclonal Antibody to Human Interleukin-5, on Eosinophilic Responses and Bronchial Hyperreactivity , 1999, Arzneimittelforschung.
[24] G H Guyatt,et al. Development and validation of a questionnaire to measure asthma control. , 1999, The European respiratory journal.
[25] R. Pauwels,et al. GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION , 1996 .
[26] C. Ulrik. Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma , 1995, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[27] J. Bousquet,et al. Eosinophilic inflammation in asthma. , 1990, The New England journal of medicine.