Splat feature classification: Detection of the presence of large retinal hemorrhages

Reliable detection of large retinal hemorrhages is important in the development of automated screening systems which can be translated into practice. In this study, we propose a novel large retinal hemorrhages detection method based on splat feature classification. Fundus photographs are partitioned into a number of splats covering the entire image. Each splat contains pixels with similar color and close spatial location. A set of distinct features is extracted within each splat. By learning properties of splats formed from blood vessels, a classifier was trained so that it can distinguish blood splats from non-blood splats. Once the blood splats, i.e. vasculature and hemorrhages, are separated from the background, the connected vasculature was removed and the remaining objects considered hemorrhage candidates. Our approach had a satisfactory performance on a test set composed of 1200 images compared to a human expert.

[1]  Max A. Viergever,et al.  Ridge-based vessel segmentation in color images of the retina , 2004, IEEE Transactions on Medical Imaging.

[2]  Bram van Ginneken,et al.  Information Fusion for Diabetic Retinopathy CAD in Digital Color Fundus Photographs , 2009, IEEE Transactions on Medical Imaging.

[3]  Gwénolé Quellec,et al.  Optimal Filter Framework for Automated, Instantaneous Detection of Lesions in Retinal Images , 2011, IEEE Transactions on Medical Imaging.

[4]  Sing Bing Kang,et al.  Stereo for Image-Based Rendering using Image Over-Segmentation , 2007, International Journal of Computer Vision.

[5]  Peter F. Sharp,et al.  Evaluation of a System for Automatic Detection of Diabetic Retinopathy From Color Fundus Photographs in a Large Population of Patients With Diabetes , 2008, Diabetes Care.

[6]  Bram van Ginneken,et al.  Automatic detection of red lesions in digital color fundus photographs , 2005, IEEE Transactions on Medical Imaging.

[7]  Gwénolé Quellec,et al.  Automated early detection of diabetic retinopathy. , 2010, Ophthalmology.

[8]  Yi-Ping Hung,et al.  Comparison between immersion-based and toboggan-based watershed image segmentation , 2006, IEEE Transactions on Image Processing.

[9]  Ho Chul Kang,et al.  A Study on Hemorrhage Detection Using Hybrid Method in Fundus Images , 2011, Journal of Digital Imaging.

[10]  Young H. Kwon,et al.  Automated segmentation of the optic disc from stereo color photographs using physiologically plausible features. , 2007, Investigative ophthalmology & visual science.

[11]  Bram van Ginneken,et al.  Comparative study of retinal vessel segmentation methods on a new publicly available database , 2004, SPIE Medical Imaging.