Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins.
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R. Plemper | D. Wolf | D H Wolf | Richard K. Plemper | A Finger | J Bordallo | R K Plemper | A. Finger | J. Bordallo | Javier Bordallo | Andreas Finger | Dieter H. Wolf
[1] J. Lippincott-Schwartz,et al. Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins , 1988, Cell.
[2] D. Smith,et al. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. , 1988, Gene.
[3] R. Schekman,et al. Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex , 1991, Nature.
[4] D. Hamer,et al. Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein , 1988, Cell.
[5] J. Marshall,et al. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis , 1990, Cell.
[6] P. Orlean,et al. Topography of glycosylation in yeast: characterization of GDPmannose transport and lumenal guanosine diphosphatase activities in Golgi-like vesicles. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[7] D. Botstein,et al. The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase. , 1992, The Journal of biological chemistry.
[8] D Botstein,et al. Structure of the yeast endoplasmic reticulum: Localization of ER proteins using immunofluorescence and immunoelectron microscopy , 1991, Yeast.
[9] J. Riordan,et al. Multiple proteolytic systems, including the proteasome, contribute to CFTR processing , 1995, Cell.
[10] J. Yewdell,et al. The Human Immunodeficiency Virus Type 1 (HIV-1) Vpu Protein Interferes with an Early Step in the Biosynthesis of Major Histocompatibility Complex (MHC) Class I Molecules , 1997, The Journal of experimental medicine.
[11] R. Schekman,et al. Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation , 1997, The EMBO journal.
[12] M. Bogyo,et al. The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol , 1996, Cell.
[13] R. W. Davis,et al. Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae , 1984, Molecular and cellular biology.
[14] M. Knop,et al. Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast. , 1996, The EMBO journal.
[15] S. Ōmura,et al. Degradation of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Endoplasmic Reticulum Membranes Is Accelerated as a Result of Increased Susceptibility to Proteolysis* , 1996, The Journal of Biological Chemistry.
[16] R. Schekman,et al. A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum , 1987, The Journal of cell biology.
[17] R. Klausner,et al. Protein degradation in the endoplasmic reticulum , 1990, Cell.
[18] Satoshi Omura,et al. Degradation of CFTR by the ubiquitin-proteasome pathway , 1995, Cell.
[19] P. Freemont. The RING Finger , 1993 .
[20] U. K. Laemmli,et al. Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.
[21] J. Brodsky,et al. Proteasome-dependent endoplasmic reticulum-associated protein degradation: An unconventional route to a familiar fate , 1996 .
[22] H. Pelham,et al. Sorting of soluble ER proteins in yeast. , 1988, The EMBO journal.
[23] T. Rapoport,et al. Evolutionary conservation of components of the protein translocation complex , 1994, Nature.
[24] H. Pelham,et al. The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast. , 1994, European journal of cell biology.
[25] G. R. Carson,et al. Depletion of cellular calcium accelerates protein degradation in the endoplasmic reticulum. , 1991, The Journal of biological chemistry.
[26] G. Fink,et al. Proteinase C (carboxypeptidase Y) mutant of yeast , 1975, Journal of bacteriology.
[27] J. Lippincott-Schwartz,et al. Degradation of proteins within the endoplasmic reticulum. , 1991, Current opinion in cell biology.
[28] L. Hendershot,et al. The modification and assembly of proteins in the endoplasmic reticulum. , 1993, Current opinion in cell biology.
[29] J. Jungmann,et al. Resistance to cadmium mediated by ubiquitin-dependent proteolysis , 1993, Nature.
[30] H. Pelham. Control of protein exit from the endoplasmic reticulum. , 1989, Annual review of cell biology.
[31] M. Knop,et al. Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast. , 1993, European journal of biochemistry.
[32] D. Kinney,et al. Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions. , 1986, Gene.
[33] M. Knop,et al. N‐glycosylation affects endoplasmic reticulum degradation of a mutated derivative of carboxypeptidase yscY in yeast , 1996, Yeast.
[34] T. Biederer,et al. Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin‐proteasome pathway. , 1996, The EMBO journal.
[35] S. Jentsch,et al. A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum , 1993, Nature.
[36] D. Wolf,et al. ER Degradation of a Misfolded Luminal Protein by the Cytosolic Ubiquitin-Proteasome Pathway , 1996, Science.
[37] J. Haimovich,et al. Degradation of secretory immunoglobulin M in B lymphocytes occurs in a postendoplasmic reticulum compartment and is mediated by a cysteine protease. , 1992, The Journal of biological chemistry.
[38] A. Fra,et al. The Endoplasmic Reticulum as a Site of Protein Degradation , 1993 .
[39] R. Plemper,et al. Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation , 1997, Nature.
[40] G. Fink,et al. The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. , 1992, Molecular biology of the cell.
[41] J. Rine,et al. Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast , 1994, The Journal of cell biology.
[42] T. Rapoport,et al. A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation , 1992, Cell.
[43] R. Serrano. H+-ATPase from plasma membranes of Saccharomyces cerevisiae and Avena sativa roots: purification and reconstitution. , 1988, Methods in enzymology.
[44] M. Yaffe,et al. Two nuclear mutations that block mitochondrial protein import in yeast. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[45] T. Rapoport,et al. Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction , 1996, Nature.
[46] A. Le,et al. Soluble aggregates of the human PiZ alpha 1-antitrypsin variant are degraded within the endoplasmic reticulum by a mechanism sensitive to inhibitors of protein synthesis. , 1992, The Journal of biological chemistry.
[47] S. Jentsch,et al. Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor , 1993, Cell.
[48] P. Freemont,et al. Does this have a familiar RING? , 1996, Trends in biochemical sciences.
[49] K. Nasmyth,et al. Yeast G1 cyclins CLN1 and CLN2 and a GAP‐like protein have a role in bud formation. , 1993, The EMBO journal.
[50] J. Rine,et al. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. , 1996, Molecular biology of the cell.
[51] Gerald R. Fink,et al. Guide to yeast genetics and molecular biology , 1993 .
[52] R. Schekman,et al. Vesicle-mediated protein sorting. , 1992, Annual review of biochemistry.