论文信息 - (R)-ACX is a novel sufonylurea compound with potent, quick and short-lasting hypoglycemic activity. - 字舞流文

(R)-ACX is a novel sufonylurea compound with potent, quick and short-lasting hypoglycemic activity.

K. Kurashima | Y. Imamura | K. Seri | H. Akita | K. Sanai

[1] T. Ohta,et al. JTT-608 controls blood glucose by enhancement of glucose-stimulated insulin secretion in normal and diabetes mellitus rats. , 1999, European journal of pharmacology.

[2] Y. Imamura,et al. Determination of absolute configuration of a metabolite (−)-hydroxyhexamide from acetohexamide, syntheses of (−)- and (+)-hydroxyhexamides and (−)- and (+)-acetoxyhexamides , 1998 .

[3] M. Akiyoshi,et al. Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (−)‐N‐(trans‐4‐isopropylcyclohexane‐carbonyl)‐d‐phenylalanine (A‐4166) , 1997, British journal of pharmacology.

[4] T. Koizumi,et al. Novel rapid- and short-acting hypoglycemic agent, a calcium(2s)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) that acts on the sulfonylurea receptor: comparison of effects between KAD-1229 and gliclazide. , 1994, The Journal of pharmacology and experimental therapeutics.

[5] J. Ward,et al. Symptomatic Hypoglycemia in NIDDM Patients Treated With Oral Hypoglycemic Agents , 1989, Diabetes Care.

[6] K. Tomita,et al. [High-performance liquid chromatographic determination of acetohexamide and its metabolite, hydroxyhexamide (author's transl)]. , 1979, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[7] R. Mcmahon,et al. The nature of the metabolites of acetohexamide in the rat and in the human. , 1965, The Journal of pharmacology and experimental therapeutics.