Glyphosate-Resistant Crops and Weeds: Now and in the Future

Glyphosate-resistant (GR) crops represent more than 80% of the 120 million ha of transgenic crops grown annually worldwide. GR crops have been rapidly adopted in soybean, maize, cotton, canola, and sugarbeet in large part because of the economic advantage of the technology, as well as the simple and superior weed control that glyphosate delivers. Furthermore, the GR crop/glyphosate technology is generally more environmentally benign than the weed management technologies that it replaced. In the Americas, except for Canada, adoption has meant continuous and intense selection pressure with glyphosate, resulting in evolution of GR weeds and shifts to weed species that are only partially controlled by glyphosate. This development is jeopardizing the benefits of this valuable technology. New transgenic crops with resistance to other herbicide classes—in some cases coupled with glyphosate resistance— will be introduced soon. If used wisely, these tools can be integrated into resistance management and prevention strategies. Greater diversity in weed management technologies is badly needed to preserve the utility of the GR crop/glyphosate technology.

[1]  D. Lema,et al.  Adoption of Herbicide Tolerant Soybeans in Argentina: An Economic Analysis , 2003 .

[2]  K. Ammann Effects of biotechnology on biodiversity: herbicide-tolerant and insect-resistant GM crops. , 2005, Trends in biotechnology.

[3]  D. Reheul,et al.  Environmental impact of herbicide regimes used with genetically modified herbicide-resistant maize , 2008, Transgenic Research.

[4]  I. Heap International survey of herbicide-resistant weeds , 1997 .

[5]  S. Padgette,et al.  Glyphosate-resistant crops: adoption, use and future considerations. , 2008, Pest management science.

[6]  O. Borggaard,et al.  Fate of glyphosate in soil and the possibility of leaching to ground and surface waters: a review. , 2008, Pest management science.

[7]  I. Jepson,et al.  Chemical‐inducible gene expression systems for plants—a review† , 1998 .

[8]  C. Mallory-Smith,et al.  Gene flow from glyphosate-resistant crops. , 2008, Pest management science.

[9]  A. G. Hornsby,et al.  Predicted impact of transgenic, herbicidetolerant corn on drinking water quality in vulnerable watersheds of the mid-western USA. , 2002, Pest management science.

[10]  G. Dill,et al.  Glyphosate-resistant crops: history, status and future. , 2005, Pest management science.

[11]  G. Stephenson,et al.  Influence of herbicide-resistant canola on the environmental impact of weed management. , 2005, Pest management science.

[12]  R Kroes,et al.  Safety evaluation and risk assessment of the herbicide Roundup and its active ingredient, glyphosate, for humans. , 2000, Regulatory toxicology and pharmacology : RTP.

[13]  M. Koziel,et al.  Characterization and plant expression of a glyphosate-tolerant enolpyruvylshikimate phosphate synthase. , 2008, Pest management science.

[14]  Richard Bennett,et al.  Environmental and human health impacts of growing genetically modified herbicide-tolerant sugar beet: a life-cycle assessment. , 2004, Plant biotechnology journal.

[15]  Linda A. Castle,et al.  Discovery and Directed Evolution of a Glyphosate Tolerance Gene , 2004, Science.

[16]  T. Clemente,et al.  Dicamba Resistance: Enlarging and Preserving Biotechnology-Based Weed Management Strategies , 2007, Science.

[17]  A. Cerdeira Environmental impacts of transgenic herbicide-resistant crops. , 2007 .

[18]  L. Gianessi,et al.  Economic impacts of glyphosate-resistant crops. , 2008, Pest management science.

[19]  Graham Brookes,et al.  GM crops: global socio-economic and environmental impacts 1996- 2007 , 2008 .

[20]  Graham Brookes,et al.  GM crops : The global economic and environmental impact-The first nine years 1996-2004 , 2005 .

[21]  Alan C. York,et al.  distribution of Glyphosate-Resistant Palmer Amaranth (Amaranthus palmeri) in Georgia and north carolina during 2005 and 2006 , 2008 .

[22]  G. Nelson,et al.  Herbicides, glyphosate resistance and acute mammalian toxicity: simulating an environmental effect of glyphosate-resistant weeds in the USA. , 2008, Pest management science.

[23]  P. Sikkema,et al.  Control of volunteer glyphosate-tolerant maize (Zea mays) in glyphosate-tolerant soybean (Glycine max). , 2006 .

[24]  Stephen O Duke,et al.  The current status and environmental impacts of glyphosate-resistant crops: a review. , 2006, Journal of environmental quality.

[25]  Robert J. Keenan,et al.  The Molecular Basis of Glyphosate Resistance by an Optimized Microbial Acetyltransferase* , 2007, Journal of Biological Chemistry.

[26]  S. Powles,et al.  Multiple herbicide resistance in a glyphosate-resistant rigid ryegrass (Lolium rigidum) population , 2004, Weed Science.

[27]  P. Gundel,et al.  Evolution of Glyphosate-Resistant Johnsongrass (Sorghum halepense) in Glyphosate-Resistant Soybean , 2007, Weed Science.

[28]  M. Owen Weed species shifts in glyphosate-resistant crops. , 2008, Pest management science.

[29]  S. Powles,et al.  Evolved glyphosate-resistant weeds around the world: lessons to be learnt. , 2008, Pest management science.

[30]  R. Keenan,et al.  Evolution of a microbial acetyltransferase for modification of glyphosate: a novel tolerance strategy. , 2005, Pest management science.

[31]  P. G. Arnison,et al.  Genetic use restriction technologies (GURTs): strategies to impede transgene movement. , 2007, Trends in plant science.

[32]  David Zilberman,et al.  Implications of gene flow in the scale-up and commercial use of biotechnology-derived crops: Economic and policy considerations , 2007 .

[33]  G. Kleter,et al.  Comparison of herbicide regimes and the associated potential environmental effects of glyphosate-resistant crops versus what they replace in Europe. , 2008, Pest management science.

[34]  Jerry W. Davis,et al.  Glyphosate-resistant Palmer amaranth (Amaranthus palmeri ) confirmed in Georgia , 2006, Weed Science.

[35]  K. N. Reddy,et al.  Integrating soil conservation practices and glyphosate-resistant crops: impacts on soil. , 2008, Pest management science.

[36]  David S. Bullock,et al.  Simulating a relative environmental effect of glyphosate-resistant soybeans , 2003 .

[37]  R. Malone,et al.  Impact of glyphosate-tolerant soybean and glufosinate-tolerant corn production on herbicide losses in surface runoff. , 2008, Journal of environmental quality.

[38]  C. Mallory-Smith,et al.  Escape and establishment of transgenic glyphosate-resistant creeping bentgrass Agrostis stolonifera in Oregon, USA: a 4-year study. , 2008 .

[39]  S. Powles,et al.  Glyphosate, paraquat and ACCase multiple herbicide resistance evolved in a Lolium rigidum biotype , 2006, Planta.

[40]  S. Duke Taking stock of herbicide-resistant crops ten years after introduction. , 2005, Pest management science.

[41]  Jerry M. Green Evolution of Glyphosate-Resistant Crop Technology , 2009 .

[42]  Jerry M. Green,et al.  New multiple-herbicide crop resistance and formulation technology to augment the utility of glyphosate. , 2008, Pest management science.

[43]  Mark J. VanGessel,et al.  Glyphosate-resistant horseweed from Delaware , 2001, Weed Science.

[44]  J. Andreassi,et al.  Response of 98140 Corn With Gat4621 and hra Transgenes to Glyphosate and ALS-Inhibiting Herbicides , 2009, Weed Science.

[45]  L. Gianessi,et al.  Plant Biotechnology : Current and Potential Impact For Improving Pest Management In U . S . Agriculture An Analysis of 40 Case Studies June 2002 Viral Resistant Citrus , 2002 .

[46]  S. Powles Evolution In Action: Glyphosate-Resistant Weeds Threaten World Crops , 2008 .

[47]  Graham Brookes,et al.  Global Impact of Biotech Crops: Socio-Economic and Environmental Effects in the First Ten Years of Commercial Use , 2007 .

[48]  S. Duke,et al.  Glyphosate: a once-in-a-century herbicide. , 2008, Pest management science.

[49]  S. Warwick,et al.  Do escaped transgenes persist in nature? The case of an herbicide resistance transgene in a weedy Brassica rapa population , 2008, Molecular ecology.

[50]  John P. Giesy,et al.  Ecotoxicological Risk Assessment for Roundup ® Herbicide , 2000 .

[51]  P. Christoffoleti,et al.  Glyphosate sustainability in South American cropping systems. , 2008, Pest management science.