Old age potentiates cold-induced tau phosphorylation: linking thermoregulatory deficit with Alzheimer's disease

[1]  A. Marette,et al.  Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease , 2016, Neurobiology of Aging.

[2]  J. Hardy,et al.  Genetics of Alzheimer’s Disease , 2014, Neurotherapeutics.

[3]  A. Marette,et al.  INSULIN REVERSES THE HIGH FAT DIET-INDUCED INCREASE IN BRAIN Aβ AND IMPROVES MEMORY IN AN ANIMAL MODEL OF ALZHEIMER'S DISEASE , 2014, Alzheimer's & Dementia.

[4]  M. Hemberg,et al.  Tau promotes neurodegeneration through global chromatin relaxation , 2014, Nature Neuroscience.

[5]  C. Cowan,et al.  Are Tau Aggregates Toxic or Protective in Tauopathies? , 2013, Front. Neurol..

[6]  I. Grundke‐Iqbal,et al.  Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration. , 2012, Journal of Alzheimer's disease : JAD.

[7]  Yihai Cao,et al.  Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice , 2012, Nature Protocols.

[8]  J. Woodgett,et al.  Molecular Neuroscience Review Article , 2009 .

[9]  F. Terro,et al.  Post-translational modifications of tau protein: Implications for Alzheimer's disease , 2011, Neurochemistry International.

[10]  Jan Nedergaard,et al.  Nonshivering thermogenesis and its adequate measurement in metabolic studies , 2011, Journal of Experimental Biology.

[11]  R. Petersen,et al.  Trends in the incidence and prevalence of Alzheimer’s disease, dementia, and cognitive impairment in the United States , 2011, Alzheimer's & Dementia.

[12]  E. Planel,et al.  Hypothermia and Alzheimer's disease neuropathogenic pathways. , 2010, Current Alzheimer research.

[13]  Rainer Lenhardt,et al.  The effect of anesthesia on body temperature control. , 2010, Frontiers in bioscience.

[14]  D. Weinert.  Circadian temperature variation and ageing , 2010, Ageing Research Reviews.

[15]  D. Dickson,et al.  Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[16]  E. Palmer,et al.  Identification and importance of brown adipose tissue in adult humans. , 2009, The New England journal of medicine.

[17]  D. Bennett,et al.  Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease , 2009, Journal of neuropathology and experimental neurology.

[18]  Kathryn Ziegler-Graham,et al.  Worldwide variation in the doubling time of Alzheimer's disease incidence rates , 2008, Alzheimer's & Dementia.

[19]  George Perry,et al.  Physiological regulation of tau phosphorylation during hibernation , 2008, Journal of neurochemistry.

[20]  Eric Ravussin,et al.  Aging, resting metabolic rate, and oxidative damage: results from the Louisiana Healthy Aging Study. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[21]  H. Koyama,et al.  Middle-aged and Elderly Outpatients Show Lower Body Temperature Responses than the Young, Even with the Same C-reactive Protein Levels , 2007, The Journal of international medical research.

[22]  R. Nelson,et al.  Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia , 2007, The Journal of Neuroscience.

[23]  G. Wolf-Klein,et al.  Older Is Colder: Temperature Range and Variation in Older People , 2005, Journal of The American Geriatrics Society.

[24]  Jesus Avila,et al.  Role of tau protein in both physiological and pathological conditions. , 2004, Physiological reviews.

[25]  Akihiko Takashima,et al.  Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease , 2004, The Journal of Neuroscience.

[26]  J. Schneider,et al.  Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. , 2004, Archives of neurology.

[27]  T. Arendt.  Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the ‘Dr. Jekyll and Mr. Hyde concept’ of Alzheimer’s disease or the yin and yang of neuroplasticity , 2003, Progress in Neurobiology.

[28]  Wolfgang Härtig,et al.  Reversible Paired Helical Filament-Like Phosphorylation of Tau Is an Adaptive Process Associated with Neuronal Plasticity in Hibernating Animals , 2003, The Journal of Neuroscience.

[29]  Patrick R. Hof,et al.  Tau protein isoforms, phosphorylation and role in neurodegenerative disorders 1 1 These authors contributed equally to this work. , 2000, Brain Research Reviews.

[30]  Bin Zhang,et al.  Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform , 1999, Neuron.

[31]  M Florez-Duquet,et al.  Cold-induced thermoregulation and biological aging. , 1998, Physiological reviews.

[32]  N. Sugarek.  Temperature Lowering After Iced Water: Enhanced Effects in the Elderly , 1986, Journal of the American Geriatrics Society.

[33]  R H Fox,et al.  Body Temperatures in the Elderly: A National Study of Physiological, Social, and Environmental Conditions , 1973, British medical journal.

[34]  F. Calon,et al.  Endogenous conversion of omega-6 into omega-3 fatty acids improves neuropathology in an animal model of Alzheimer's disease. , 2011, Journal of Alzheimer's disease : JAD.

[35]  Michèle Allard,et al.  Brain fuel metabolism, aging, and Alzheimer's disease. , 2011, Nutrition (Burbank, Los Angeles County, Calif.).

[36]  F. LaFerla,et al.  Alzheimer's disease. , 2010, The New England journal of medicine.

[37]  I. Grundke‐Iqbal,et al.  Anesthesia induces phosphorylation of tau. , 2009, Journal of Alzheimer's disease : JAD.

[38]  D. Bennett,et al.  Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease. , 2007, Journal of Alzheimer's disease : JAD.

[39]  D. Bennett,et al.  Biochemical Characterization of Aβ and Tau Pathologies in Mild Cognitive Impairment and Alzheimer's Disease , 2007 .

[40]  Akihiko Takashima,et al.  GSK-3 is essential in the pathogenesis of Alzheimer's disease. , 2006, Journal of Alzheimer's disease : JAD.

[41]  W Larry Kenney,et al.  CALL FOR PAPERS Physiology and Pharmacology of Temperature Regulation Impaired defense of core temperature in aged humans during mild cold stress , 2006 .

[42]  T. Howell.  Oral temperature range in old age. , 1975, Gerontologia clinica.