The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis.
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A. Yoshimura | R. Okamoto | Toshihiko Suzuki | H. Ashida | Y. Nemoto | M. Tomura | J. Niess | Toshiaki Teratani | H. Melhem | Y. Mikami | Yuzo Koda | T. Sujino | K. Miyamoto | Y. Yoshimatsu | Y. Harada | S. Suzuki | T. Kanai | Toru Suzuki | Toshiro Sato | Yuki Yonemoto | Kenji Tanaka | Yosuke Harada
[1] H. Madhani,et al. Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system. , 2023, Immunity.
[2] H. Weiner,et al. Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting , 2023, Cell.
[3] C. Benoist,et al. The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries. , 2023, Immunity.
[4] A. Bevilacqua,et al. Gut-Microbiota, and Multiple Sclerosis: Background, Evidence, and Perspectives , 2023, Nutrients.
[5] Xuan Huang,et al. ERR-activated GPR35 promotes immune infiltration level of macrophages in gastric cancer tissues , 2022, Cell Death Discovery.
[6] A. Mohamadkhani,et al. Dynamic changes in kynurenine pathway metabolites in multiple sclerosis: A systematic review , 2022, Frontiers in Immunology.
[7] A. MacKenzie-Graham,et al. Chronic experimental autoimmune encephalomyelitis is an excellent model to study neuroaxonal degeneration in multiple sclerosis , 2022, Frontiers in Molecular Neuroscience.
[8] F. Shi,et al. Bone marrow hematopoiesis drives multiple sclerosis progression , 2022, Cell.
[9] Jeff Trent,et al. Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial , 2022, Nature Medicine.
[10] J. Cyster,et al. GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA , 2022, Cell.
[11] A. Regev,et al. Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity , 2021, Cell.
[12] J. Niess,et al. GPR35 in Intestinal Diseases: From Risk Gene to Function , 2021, Frontiers in Immunology.
[13] M. Leboyer,et al. Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders , 2021, Frontiers in Immunology.
[14] Susumu Tomono,et al. Clostridium butyricum MIYAIRI 588 Modifies Bacterial Composition under Antibiotic-Induced Dysbiosis for the Activation of Interactions via Lipid Metabolism between the Gut Microbiome and the Host , 2021, Biomedicines.
[15] Xiuli Lin,et al. Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice , 2021, Journal of translational medicine.
[16] T. Kanai,et al. CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells , 2021, Nature Communications.
[17] M. Doyle,et al. Interfacing Seurat with the R tidy universe , 2021, bioRxiv.
[18] T. Karlsen,et al. Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment , 2021, Gut.
[19] Toshiro Sato,et al. An organoid-based organ-repurposing approach to treat short bowel syndrome , 2021, Nature.
[20] N. Kamada,et al. The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine–Dependent but GPR43/109a-Independent Mechanisms , 2021, The Journal of Immunology.
[21] T. Kanai,et al. C-C motif chemokine receptor 9 regulates obesity-induced insulin resistance via inflammation of the small intestine in mice , 2021, Diabetologia.
[22] Paul J. McMurdie,et al. Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease , 2021, Gut microbes.
[23] Raphael Gottardo,et al. Integrated analysis of multimodal single-cell data , 2020, Cell.
[24] S. Damak,et al. Activation of the G-protein coupled receptor GPR35 by human milk oligosaccharides through different pathways , 2020, Scientific Reports.
[25] Christopher C. Overall,et al. Experimental autoimmune encephalomyelitis is associated with changes of the microbiota composition in the gastrointestinal tract , 2020, Scientific Reports.
[26] M. Hattori,et al. Gut microorganisms act together to exacerbate inflammation in spinal cords , 2020, Nature.
[27] P. Hruz,et al. Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis. , 2020, Cell reports.
[28] M. Hattori,et al. The liver–brain–gut neural arc maintains the Treg cell niche in the gut , 2020, Nature.
[29] L. Vécsei,et al. Kynurenines in the Pathogenesis of Multiple Sclerosis: Therapeutic Perspectives , 2020, Cells.
[30] Gavin M Douglas,et al. PICRUSt2 for prediction of metagenome functions , 2020, Nature Biotechnology.
[31] D. Littman,et al. Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes , 2020, bioRxiv.
[32] S. Miyake,et al. Gut dysbiosis and multiple sclerosis. , 2020, Clinical immunology.
[33] L. Boon,et al. Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells. , 2020, Immunity.
[34] M. Ishii,et al. Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1 , 2019, Nature Immunology.
[35] M. Shinohara,et al. Pattern Recognition Receptors in Multiple Sclerosis and Its Animal Models , 2019, Front. Immunol..
[36] Fabian J Theis,et al. Generalizing RNA velocity to transient cell states through dynamical modeling , 2019, Nature Biotechnology.
[37] P. Rosenstiel,et al. Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology , 2019, Nature Communications.
[38] J. Schrenzel,et al. Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis. , 2019, Cell reports.
[39] Katsuaki Sato,et al. Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35. , 2019, The Journal of clinical investigation.
[40] William A. Walters,et al. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 , 2019, Nature Biotechnology.
[41] Xiuli Lin,et al. Gut Microbiota Interventions With Clostridium butyricum and Norfloxacin Modulate Immune Response in Experimental Autoimmune Encephalomyelitis Mice , 2019, Front. Immunol..
[42] Aviv Regev,et al. Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis , 2019, Cell.
[43] D. Im,et al. Lodoxamide Attenuates Hepatic Fibrosis in Mice: Involvement of GPR35 , 2019, Biomolecules & therapeutics.
[44] G. Castelo-Branco,et al. An Atlas of Vagal Sensory Neurons and Their Molecular Specialization , 2019, Cell reports.
[45] D. Esterházy,et al. Compartmentalized gut lymph node drainage dictates adaptive immune responses , 2019, Nature.
[46] M. Hattori,et al. Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis , 2019, Nature Microbiology.
[47] Andrew R. Bassett,et al. GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump , 2019, Science Signaling.
[48] T. McGaha,et al. The Aryl Hydrocarbon Receptor: Connecting Immunity to the Microenvironment. , 2018, Trends in immunology.
[49] Donovan H. Parks,et al. AnnoTree: visualization and exploration of a functionally annotated microbial tree of life , 2018, bioRxiv.
[50] T. Kanai,et al. Toll-Like Receptor 7 Agonist–Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells , 2018, Cellular and molecular gastroenterology and hepatology.
[51] Erik Sundström,et al. RNA velocity of single cells , 2018, Nature.
[52] M. Bissonnette,et al. Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis. , 2018, Inflammatory bowel diseases.
[53] G. Weinstock,et al. Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota. , 2018, Cell metabolism.
[54] Clare Baecher-Allan,et al. Multiple Sclerosis: Mechanisms and Immunotherapy , 2018, Neuron.
[55] Yu-Wei Wu. ezTree: an automated pipeline for identifying phylogenetic marker genes and inferring evolutionary relationships among uncultivated prokaryotic draft genomes , 2018, BMC Genomics.
[56] K. Berer,et al. Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice , 2017, Proceedings of the National Academy of Sciences.
[57] Stephen L. Hauser,et al. Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models , 2017, Proceedings of the National Academy of Sciences.
[58] N. Hamouda,et al. G protein‐coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells , 2017, Pharmacological research.
[59] M. Hattori,et al. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. , 2017, Cell reports.
[60] Robin Patel,et al. Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease. , 2017, Cell reports.
[61] A. Mangalam,et al. Gut microbiome in multiple sclerosis: The players involved and the roles they play , 2017, Gut microbes.
[62] T. Honda,et al. Regulatory T cells with superior immunosuppressive capacity emigrate from the inflamed colon to draining lymph nodes , 2017, Mucosal Immunology.
[63] Hailiang Huang,et al. Fine-mapping inflammatory bowel disease loci to single variant resolution , 2017, Nature.
[64] Geet Duggal,et al. Salmon: fast and bias-aware quantification of transcript expression using dual-phase inference , 2017, Nature Methods.
[65] Bruce V. Taylor,et al. Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression , 2017, Scientific Reports.
[66] Johannes U. Mayer,et al. Tissue-Specific Differentiation of Colonic Macrophages Requires TGFβ Receptor Mediated Signalling , 2017, Mucosal Immunology.
[67] C. Benoist,et al. Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice , 2016, Proceedings of the National Academy of Sciences.
[68] B. Stockinger,et al. Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney , 2016, Immunity.
[69] M. Kanehisa,et al. BlastKOALA and GhostKOALA: KEGG Tools for Functional Characterization of Genome and Metagenome Sequences. , 2016, Journal of molecular biology.
[70] M. Robinson,et al. Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences. , 2015, F1000Research.
[71] M. Hattori,et al. Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells , 2015, Cell.
[72] M. Hattori,et al. Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters , 2015, PloS one.
[73] Liza Konnikova,et al. Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells , 2015, Science.
[74] T. Hohl,et al. Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses. , 2015, Cell reports.
[75] L. Vécsei,et al. Kynurenines and Multiple Sclerosis: The Dialogue between the Immune System and the Central Nervous System , 2015, International journal of molecular sciences.
[76] R. Morita,et al. Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells. , 2015, Immunity.
[77] M. Rovaris,et al. Indoleamine 2,3 Dioxygenase (IDO) Expression and Activity in Relapsing- Remitting Multiple Sclerosis , 2015, PloS one.
[78] Rob Knight,et al. Analysis of composition of microbiomes: a novel method for studying microbial composition , 2015, Microbial ecology in health and disease.
[79] Evan Z. Macosko,et al. Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets , 2015, Cell.
[80] G. Milligan,et al. G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease , 2015, Front. Pharmacol..
[81] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[82] Shane J. Neph,et al. A comparative encyclopedia of DNA elements in the mouse genome , 2014, Nature.
[83] Torsten Seemann,et al. Prokka: rapid prokaryotic genome annotation , 2014, Bioinform..
[84] G. Friedlander,et al. Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis. , 2014, Immunity.
[85] J. Yates,et al. Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor , 2013, Cell.
[86] M. Tomita,et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells , 2013, Nature.
[87] W. Garrett,et al. The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis , 2013, Science.
[88] J. Goverman,et al. Modeling the heterogeneity of multiple sclerosis in animals. , 2013, Trends in immunology.
[89] M. Hattori,et al. Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota , 2013, Nature.
[90] T. Hibi,et al. A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice. , 2013, Cell host & microbe.
[91] Susan Holmes,et al. phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data , 2013, PloS one.
[92] Pelin Yilmaz,et al. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools , 2012, Nucleic Acids Res..
[93] K. Adachi,et al. Sphingosine 1-Phosphate Receptor 1 as a Useful Target for Treatment of Multiple Sclerosis , 2012, Pharmaceuticals.
[94] Ye Fang,et al. Multiple tyrosine metabolites are GPR35 agonists , 2012, Scientific Reports.
[95] K. Berer,et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination , 2011, Nature.
[96] S. Sakoda,et al. The Lactic Acid Bacterium Pediococcus acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-Producing Regulatory T Cells , 2011, PloS one.
[97] C. Constantinescu,et al. Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS) , 2011, British journal of pharmacology.
[98] F. Safavi,et al. The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF , 2011, Nature Immunology.
[99] S. Mazmanian,et al. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis , 2010, Proceedings of the National Academy of Sciences.
[100] D. Kasper,et al. A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease , 2010, Mucosal Immunology.
[101] Dan R. Littman,et al. Th17 and Regulatory T Cells in Mediating and Restraining Inflammation , 2010, Cell.
[102] P. Legendre,et al. Associations between species and groups of sites: indices and statistical inference. , 2009, Ecology.
[103] Davis J. McCarthy,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[104] R. Nurieva,et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. , 2009, Immunity.
[105] Irah L. King,et al. Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. , 2009, Blood.
[106] Atsushi Miyawaki,et al. Monitoring cellular movement in vivo with photoconvertible fluorescence protein “Kaede” transgenic mice , 2008, Proceedings of the National Academy of Sciences.
[107] B. Pulendran,et al. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17–producing T cell responses , 2007, Nature Immunology.
[108] W. Turski,et al. Astrocytic activation in relation to inflammatory markers during clinical exacerbation of relapsing-remitting multiple sclerosis , 2007, Journal of Neural Transmission.
[109] J. Reagan,et al. Kynurenic Acid as a Ligand for Orphan G Protein-coupled Receptor GPR35* , 2006, Journal of Biological Chemistry.
[110] H. Weiner,et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells , 2006, Nature.
[111] R. D. Hatton,et al. Transforming growth factor-β induces development of the TH17 lineage , 2006, Nature.
[112] P. Klivényi,et al. Kynurenine metabolism in multiple sclerosis , 2005, Acta neurologica Scandinavica.
[113] T. Macdonald,et al. Immunity, Inflammation, and Allergy in the Gut , 2005, Science.
[114] Steffen Jung,et al. Blood monocytes consist of two principal subsets with distinct migratory properties. , 2003, Immunity.
[115] R. Kastelein,et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain , 2003, Nature.
[116] C. Sasakawa,et al. vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri , 1992, Journal of bacteriology.
[117] R. Schwarcz,et al. Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism , 1991, Journal of neurochemistry.
[118] Nicholas L. Bormann,et al. scRepertoire: An R-based toolkit for single-cell immune receptor analysis. , 2020, F1000Research.
[119] R. Gold,et al. Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine. , 2016, Immunity.