A Multi-Cohort Study of Polymorphisms in the GH/IGF Axis and Physical Capability: The HALCyon Programme
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Tom R. Gaunt | I. Deary | C. Cooper | J. Starr | S. Harris | I. Day | Y. Ben-Shlomo | M. Kumari | D. Kuh | D. Gunnell | R. Cooper | R. Hardy | Richard M. Martin | T. Alfred | A. Sayer | S. Harris | C. Cooper | C. Cooper
[1] M. D. de Wit,et al. Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions , 2012, Annals of the rheumatic diseases.
[2] C. Gieger,et al. A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. , 2011, Human molecular genetics.
[3] A. Yashin,et al. Heritability estimates of endophenotypes of long and health life: the Long Life Family Study. , 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.
[4] Rebecca Hardy,et al. Objective measures of physical capability and subsequent health: a systematic review , 2010, Age and ageing.
[5] D. Kuh,et al. Objectively measured physical capability levels and mortality: systematic review and meta-analysis , 2010, BMJ : British Medical Journal.
[6] Ayellet V. Segrè,et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height , 2010, Nature.
[7] Jing Hua Zhao,et al. Physical Activity Attenuates the Genetic Predisposition to Obesity in 20,000 Men and Women from EPIC-Norfolk Prospective Population Study , 2010, PLoS medicine.
[8] W. Willett,et al. A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians. , 2010, Human molecular genetics.
[9] D. Cooper,et al. Characterisation of a functional intronic polymorphism in the human growth hormone (GHI) gene , 2010, Human Genomics.
[10] Y. Kamatani,et al. A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. , 2010, Human molecular genetics.
[11] E. Hoffman,et al. A polymorphism near IGF1 is associated with body composition and muscle function in women from the Health, Aging, and Body Composition Study , 2010, European Journal of Applied Physiology.
[12] P. Delmas,et al. Rapid loss of appendicular skeletal muscle mass is associated with higher all-cause mortality in older men: the prospective MINOS study. , 2010, The American journal of clinical nutrition.
[13] P. Visscher,et al. Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time. , 2010, American journal of human genetics.
[14] S. Land,et al. Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women , 2010, Journal of cancer epidemiology.
[15] R. Riley,et al. Meta-analysis of individual participant data: rationale, conduct, and reporting , 2010, BMJ : British Medical Journal.
[16] C. Cooper,et al. Cohort profile: The Hertfordshire Ageing Study (HAS). , 2010, International journal of epidemiology.
[17] Christian Gieger,et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk , 2010, Nature Genetics.
[18] Jean Tichet,et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia , 2009, Nature Genetics.
[19] M. Pirmohamed,et al. The d3/fl-GH receptor gene polymorphism does not influence quality of life and body composition in GH-deficient adults receiving GH replacement therapy. , 2009, European journal of endocrinology.
[20] Ali Amin Al Olama,et al. Identification of seven new prostate cancer susceptibility loci through a genome-wide association study , 2009, Nature Genetics.
[21] P. Cawthon,et al. Sarcopenia: etiology, clinical consequences, intervention, and assessment , 2009, Osteoporosis International.
[22] D. Clemmons. Role of IGF-I in skeletal muscle mass maintenance , 2009, Trends in Endocrinology & Metabolism.
[23] Hongbing Shen,et al. Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies , 2009, European Journal of Human Genetics.
[24] J. Ioannidis,et al. Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. , 2009, Journal of clinical epidemiology.
[25] S. Levy,et al. Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. , 2009, American journal of human genetics.
[26] R. Baserga. The insulin receptor substrate-1: a biomarker for cancer? , 2009, Experimental cell research.
[27] J. Kopchick,et al. Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models. , 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
[28] S. Gruber,et al. Recreational Physical Activity Modifies the Association Between a Common GH1 Polymorphism and Colorectal Cancer Risk , 2008, Cancer Epidemiology Biomarkers & Prevention.
[29] R. Recker,et al. Comprehensive association analyses of IGF1, ESR2, and CYP17 genes with adult height in Caucasians , 2008, European Journal of Human Genetics.
[30] S. Giovannini,et al. Modulation of GH/IGF-1 axis: Potential strategies to counteract sarcopenia in older adults , 2008, Mechanisms of Ageing and Development.
[31] M. Pike,et al. IGF-1, IGFBP-1, and IGFBP-3 Polymorphisms Predict Circulating IGF Levels but Not Breast Cancer Risk: Findings from the Breast and Prostate Cancer Cohort Consortium (BPC3) , 2008, PloS one.
[32] K. Lunetta. Genetic Association Studies , 2008, Circulation.
[33] C. Velloso. Regulation of muscle mass by growth hormone and IGF‐I , 2008, British journal of pharmacology.
[34] A. Ashworth,et al. Identification of genetic variants that influence circulating IGF1 levels: a targeted search strategy. , 2008, Human molecular genetics.
[35] D. Melzer,et al. Epidemiology of balance and dizziness in a national population: findings from the English Longitudinal Study of Ageing. , 2008, Age and ageing.
[36] J. Thompson,et al. How should we use information about HWE in the meta-analyses of genetic association studies? , 2008, International journal of epidemiology.
[37] James M Hagberg,et al. Influence of promoter region variants of insulin-like growth factor pathway genes on the strength-training response of muscle phenotypes in older adults. , 2007, Journal of applied physiology.
[38] M. Sandhu,et al. Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women. , 2007, The Journal of clinical endocrinology and metabolism.
[39] J. Hirschhorn,et al. Common genetic variation in eight genes of the GH/IGF1 axis does not contribute to adult height variation , 2007, Human Genetics.
[40] James Strait,et al. Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits , 2007, PLoS genetics.
[41] E. Hoffman,et al. IGF-II gene region polymorphisms related to exertional muscle damage. , 2007, Journal of applied physiology.
[42] D. Cole,et al. Relationship of the human growth hormone receptor exon 3 genotype with final adult height and bone mineral density. , 2007, The Journal of clinical endocrinology and metabolism.
[43] H. Grönberg,et al. Haplotype-Based Analysis of Common Variation in the Growth Hormone Receptor Gene and Prostate Cancer Risk , 2007, Cancer Epidemiology Biomarkers & Prevention.
[44] Tom R. Gaunt,et al. Refined Association Mapping for a Quantitative Trait: Weight in the H19‐IGF2‐INS‐TH Region , 2006, Annals of human genetics.
[45] P. Kelly,et al. Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[46] D. Kuh,et al. Cohort Profile: The 1946 National Birth Cohort (MRC National Survey of Health and Development). , 2006, International journal of epidemiology.
[47] T. Noakes,et al. Growth hormone 1 (GH1) gene and performance and post-race rectal temperature during the South African Ironman triathlon , 2006, British Journal of Sports Medicine.
[48] I. Janssen. Influence of Sarcopenia on the Development of Physical Disability: The Cardiovascular Health Study , 2006, Journal of the American Geriatrics Society.
[49] C. Cooper,et al. Cohort profile: the Hertfordshire cohort study. , 2005, International journal of epidemiology.
[50] R. Ebstein,et al. Association between the insulin-like growth factor 2 gene (IGF2) and scores on the Eating Attitudes Test in nonclinical subjects: a family-based study. , 2005, The American journal of psychiatry.
[51] S. Bandinelli,et al. Insulin resistance and muscle strength in older persons. , 2005, The journals of gerontology. Series A, Biological sciences and medical sciences.
[52] G. Smith,et al. Cohort profile: The Boyd Orr cohort--an historical cohort study based on the 65 year follow-up of the Carnegie Survey of Diet and Health (1937-39). , 2005, International journal of epidemiology.
[53] R. Wolff,et al. Insulin-Like Growth Factor Pathway Polymorphisms Associated with Body Size in Hispanic and Non-Hispanic White Women , 2005, Cancer Epidemiology Biomarkers & Prevention.
[54] B. Zwaan,et al. Reduced insulin/IGF‐1 signalling and human longevity , 2005, Aging cell.
[55] R. Hardy,et al. Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditions. , 2005, The journals of gerontology. Series A, Biological sciences and medical sciences.
[56] R. Ebstein,et al. Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study , 2005, Mechanisms of Ageing and Development.
[57] M. Päivänsalo,et al. IGF‐I concentrations are positively associated with carotid artery atherosclerosis in women , 2005, Annals of medicine.
[58] P. Delmas,et al. Low Skeletal Muscle Mass Is Associated With Poor Structural Parameters of Bone and Impaired Balance in Elderly Men—The MINOS Study , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[59] E. Metter,et al. Insulin-like growth factor-2 genotype, fat-free mass, and muscle performance across the adult life span. , 2004, Journal of applied physiology.
[60] X. Shu,et al. Genetic polymorphisms in the human growth hormone‐1 gene (GH1) and the risk of breast carcinoma , 2004, Cancer.
[61] Luigi Ferrucci,et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. , 2003, Journal of applied physiology.
[62] D. Altman,et al. Measuring inconsistency in meta-analyses , 2003, BMJ : British Medical Journal.
[63] C. Cooper,et al. Polymorphism of the IGF2 gene, birth weight and grip strength in adult men. , 2002, Age and ageing.
[64] L. Le Marchand,et al. Association of a common polymorphism in the human GH1 gene with colorectal neoplasia. , 2002, Journal of the National Cancer Institute.
[65] Tom R. Gaunt,et al. Positive associations between single nucleotide polymorphisms in the IGF2 gene region and body mass index in adult males. , 2001, Human molecular genetics.
[66] R. Dennis Cook,et al. Detection of Influential Observation in Linear Regression , 2000, Technometrics.
[67] S. Heymsfield,et al. Epidemiology of sarcopenia among the elderly in New Mexico. , 1998, American journal of epidemiology.
[68] R B Wallace,et al. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. , 1995, The New England journal of medicine.
[69] Diane Podsiadlo,et al. The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons , 1991, Journal of the American Geriatrics Society.
[70] P. Bougnères. The exon-3 deletion of the growth hormone receptor (GHR) gene still has a limited impact in clinical endocrinology. , 2010, The Journal of clinical endocrinology and metabolism.
[71] B. Han,et al. Identification of 15 loci influencing height in a Korean population , 2010, Journal of Human Genetics.
[72] Christian Gieger,et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation , 2009, Nature Genetics.
[73] G. Abellán van Kan. Epidemiology and consequences of sarcopenia , 2009, The journal of nutrition, health & aging.
[74] Wj Gauderman,et al. QUANTO 1.1: A computer program for power and sample size calculations for genetic-epidemiology studies , 2006 .
[75] Tom R. Gaunt,et al. Experience applying light typerTM methodology to human SNPs relevant to growth and cardiovascular risk , 2006 .
[76] M. Rudnicki,et al. Cellular and molecular regulation of muscle regeneration. , 2004, Physiological reviews.
[77] J. Kaprio,et al. Heritability of maximal isometric muscle strength in older female twins. , 2004, Journal of applied physiology.
[78] Ian J Deary,et al. The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947. , 2004, Journal of personality and social psychology.
[79] J. Nazroo. Health, wealth and lifestyles of the older population in England: The 2002 English Longitudinal Study of Ageing , 2003 .
[80] Ack,et al. LOWER-EXTREMITY FUNCTION IN PERSONS OVER THE AGE OF 70 YEARS AS A PREDICTOR OF SUBSEQUENT DISABILITY , 2001 .
[81] Obert,et al. Effects of human growth hormone in men over 60 years old. , 1990, The New England journal of medicine.
[82] D. Mccarty,et al. Simple method for measurement of lower extremity muscle strength. , 1985, The American journal of medicine.
[83] A. Bartke. Printed in U.S.A. Copyright © 2005 by The Endocrine Society doi: 10.1210/en.2005-0411 Minireview: Role of the Growth Hormone/Insulin-Like Growth Factor System in Mammalian Aging , 2022 .