论文信息 - Does the skin tell the somatosensory cortex how to construct a map of the periphery?

Does the skin tell the somatosensory cortex how to construct a map of the periphery?

When the muzzle of a mouse bears an occasional extra whisker, the corresponding barrelfield (in the contralateral somatosensory cortex) contains an extra barrel in a topologically equivalent place and vice versa. Since the pattern of vibrissal follicles is laid down 7 days before birth and that of the barrels 3 days after birth, the former pattern appears to be responsible for the establishment of the latter. We propose that the answer to the title's question is yes.

H. Loos | J. Dörfl | Hendrik van der Loos | Josef Dörfl

[1] H. Loos. Structural changes in the cerebral cortex upon modification of the periphery: barrels in somatosensory cortex , 1977 .

[2] T. Woolsey,et al. The structural organization of layer IV in the somatosensory region (S I) of mouse cerebral cortex , 1970 .

[3] H. Loos. Barreloids in mouse somatosensory thalamus , 1976, Neuroscience Letters.

[4] T. Woolsey,et al. A proportional relationship between peripheral innervation density and cortical neuron number in the somatosensory system of the mouse , 1975, Brain Research.

[5] H. van der Loos,et al. Development of the barrels and barrel field in the somatosensory cortex of the mouse , 1977, The Journal of comparative neurology.

[6] H. Killackey,et al. The organization of specific thalamocortical projections to the posteromedial barrel subfield of the rat somatic sensory cortex , 1975, Brain Research.

[7] T. Woolsey,et al. Somatosensory Cortex: Structural Alterations following Early Injury to Sense Organs , 1973, Science.

[8] D. Frost,et al. Barrels in somatosensory cortex of normal and reeler mutant mice , 1976, Neuroscience Letters.

[9] D. Jeanmonod,et al. Mouse somatosensory cortex: Development of the alterations in the barrel field which are caused by injury to the vibrissal follicles , 1977, Neuroscience Letters.