Trafficking of Normal Stem Cells and Metastasis of Cancer Stem Cells Involve Similar Mechanisms: Pivotal Role of the SDF‐1–CXCR4 Axis
暂无分享,去创建一个
M. Ratajczak | M. Kucia | W. Wojakowski | J. Ratajczak | A. Janowska-Wieczorek | R. Reca | J. Wanzeck | K. Miekus
[1] V. Goldberg,et al. FGF‐2 enhances the mitotic and chondrogenic potentials of human adult bone marrow‐derived mesenchymal stem cells , 2005, Journal of cellular physiology.
[2] P. Carmeliet,et al. A Novel Role for Vascular Endothelial Growth Factor as an Autocrine Survival Factor for Embryonic Stem Cells during Hypoxia* , 2005, Journal of Biological Chemistry.
[3] M. Ratajczak,et al. Bone marrow as a source of circulating CXCR4+ tissue‐committed stem cells , 2005, Biology of the cell.
[4] J. Platt,et al. Selective suppression of Toll‐like receptor 4 activation by chemokine receptor 4 , 2005, FEBS letters.
[5] Lieve Moons,et al. CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. , 2005, Cancer research.
[6] Seiji Fukuda,et al. Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1. , 2005, Blood.
[7] E. Scott,et al. SDF-1 is both necessary and sufficient to promote proliferative retinopathy. , 2005, The Journal of clinical investigation.
[8] R. Alon,et al. Atypical PKC-ζ regulates SDF-1–mediated migration and development of human CD34+ progenitor cells , 2005 .
[9] R. Bolli,et al. Cells Expressing Early Cardiac Markers Reside in the Bone Marrow and Are Mobilized Into the Peripheral Blood After Myocardial Infarction , 2004, Circulation research.
[10] K. Forsberg-Nilsson,et al. Stem cell factor is a chemoattractant and a survival factor for CNS stem cells. , 2004, Experimental cell research.
[11] G. Schettini,et al. CXCR4 Activation Induces Epidermal Growth Factor Receptor Transactivation in an Ovarian Cancer Cell Line , 2004, Annals of the New York Academy of Sciences.
[12] Yan Huang,et al. Stromal Cell–Derived Factor-1α Plays a Critical Role in Stem Cell Recruitment to the Heart After Myocardial Infarction but Is Not Sufficient to Induce Homing in the Absence of Injury , 2004, Circulation.
[13] R. Henkelman,et al. Identification of human brain tumour initiating cells , 2004, Nature.
[14] M. Ratajczak,et al. CXCR4 Is a PAX Family Transcription Factor Regulated Gene. , 2004 .
[15] M. Ratajczak,et al. A Potential New Application of Mobilization/Leukapheresis for Enrichment of Peripheral Blood in Circulating Non-Hematopoietic CXCR4+CD45− Tissue-Committed Stem Cells (TCSC) for Organ/Tissue Regeneration. , 2004 .
[16] M. Tendera,et al. Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ Stem Cells, and Mononuclear Cells Expressing Early Cardiac, Muscle, and Endothelial Markers Into Peripheral Blood in Patients With Acute Myocardial Infarction , 2004, Circulation.
[17] C. Corless,et al. Transplanted human bone marrow contributes to vascular endothelium. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[18] T. Kilpatrick,et al. LIF receptor signaling modulates neural stem cell renewal , 2004, Molecular and Cellular Neuroscience.
[19] C. Donadoni,et al. Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues. , 2004, Brain : a journal of neurology.
[20] S. Zucker,et al. CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma. , 2004, Cancer letters.
[21] Yoshinori Murakami,et al. Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia. , 2004, Blood.
[22] J. Pouysségur,et al. HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs. , 2004, Biochemical pharmacology.
[23] G. Meinhardt,et al. The HMG-CoA reductase inhibitor simvastatin overcomes cell adhesion-mediated drug resistance in multiple myeloma by geranylgeranylation of Rho protein and activation of Rho kinase. , 2004, Blood.
[24] W. Greene. The brightening future of HIV therapeutics , 2004, Nature Immunology.
[25] M. Ratajczak,et al. Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells , 2004, Leukemia.
[26] H. Broxmeyer,et al. Modulation of Hematopoietic Stem Cell Homing and Engraftment by CD26 , 2004, Science.
[27] Oana A. Tomescu,et al. Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression , 2004, Laboratory Investigation.
[28] Geoffrey C Gurtner,et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1 , 2004, Nature Medicine.
[29] D. Livingston,et al. Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway. , 2004, Cancer cell.
[30] Seung‐Jung Park,et al. Lysophosphatidylcholine up‐regulates CXCR4 chemokine receptor expression in human CD4 T cells , 2004, Journal of leukocyte biology.
[31] G. Seitz,et al. The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells. , 2004, Blood.
[32] J. Lord,et al. Topical Glucocorticoid Therapy Directly Induces Up-Regulation of Functional CXCR4 on Primed T Lymphocytes in the Aqueous Humor of Patients with Uveitis1 , 2004, The Journal of Immunology.
[33] S. Bae,et al. Adult bone marrow-derived cells trans-differentiating into insulin-producing cells for the treatment of type I diabetes , 2004, Laboratory Investigation.
[34] D. Wong,et al. Small peptide analogs to stromal derived factor-1 enhance chemotactic migration of human and mouse hematopoietic cells. , 2004, Experimental hematology.
[35] R. Alon,et al. CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow. , 2004, Blood.
[36] A. Nagler,et al. Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. , 2004, Blood.
[37] Arnon Nagler,et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. , 2004, Cancer research.
[38] N. Longo,et al. Stromal Cell-Derived Factor-1α Promotes Melanoma Cell Invasion across Basement Membranes Involving Stimulation of Membrane-Type 1 Matrix Metalloproteinase and Rho GTPase Activities , 2004, Cancer Research.
[39] W. Fu,et al. The presence of FGF2 signaling determines whether beta-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells. , 2004, Developmental biology.
[40] E. Fuchs,et al. Socializing with the Neighbors Stem Cells and Their Niche , 2004, Cell.
[41] J. Dipersio,et al. Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[42] D. Hess,et al. SDF‐1 (CXCL12) Is Upregulated in the Ischemic Penumbra Following Stroke: Association with Bone Marrow Cell Homing to Injury , 2004, Journal of neuropathology and experimental neurology.
[43] J. Kiss,et al. VEGF is a chemoattractant for FGF-2–stimulated neural progenitors , 2003, The Journal of cell biology.
[44] S. Salani,et al. Neuronal differentiation of murine bone marrow Thy-1- and Sca-1-positive cells. , 2003, Journal of hematotherapy & stem cell research.
[45] Michael F. Clarke,et al. Applying the principles of stem-cell biology to cancer , 2003, Nature Reviews Cancer.
[46] R. Zhao,et al. Multiorgan engraftment and multilineage differentiation by human fetal bone marrow Flk1+/CD31-/CD34- Progenitors. , 2003, Journal of hematotherapy & stem cell research.
[47] P. Houghton,et al. Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy. , 2003, Cancer research.
[48] Tanja Hartmann,et al. Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells , 2003, Oncogene.
[49] S. Saccani,et al. Regulation of the Chemokine Receptor CXCR4 by Hypoxia , 2003, The Journal of experimental medicine.
[50] David A. Williams,et al. Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling , 2003, Science.
[51] B. Wood,et al. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. , 2003, Blood.
[52] Masahiro Miyazaki,et al. Participation of adult mouse bone marrow cells in reconstitution of skin. , 2003, The American journal of pathology.
[53] G. Dontu,et al. Stem cells in normal breast development and breast cancer , 2003, Breast Cancer Research.
[54] F. Garcia-sanchez,et al. Transforming growth factor-beta1 down-regulates expression of chemokine stromal cell-derived factor-1: functional consequences in cell migration and adhesion. , 2003, Blood.
[55] Eric J Topol,et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy , 2003, The Lancet.
[56] G. Stamatoyannopoulos,et al. Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. , 2003, Cancer research.
[57] Z. Estrov,et al. Adult stem cells for tissue repair - a new therapeutic concept? , 2003, The New England journal of medicine.
[58] A. Nagler,et al. HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver. , 2003, The Journal of clinical investigation.
[59] N. Qian,et al. Distinct Role of ZAP-70 and Src Homology 2 Domain-Containing Leukocyte Protein of 76 kDa in the Prolonged Activation of Extracellular Signal-Regulated Protein Kinase by the Stromal Cell-Derived Factor-1α/CXCL12 Chemokine1 , 2003, The Journal of Immunology.
[60] H. Nakshatri,et al. NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4* , 2003, Journal of Biological Chemistry.
[61] Shahin Rafii,et al. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration , 2003, Nature Medicine.
[62] G. Downey,et al. L-selectin stimulation enhances functional expression of surface CXCR4 in lymphocytes: implications for cellular activation during adhesion and migration. , 2003, Blood.
[63] K. Pienta,et al. Expression of CXCR4 and CXCL12 (SDF‐1) in human prostate cancers (PCa) in vivo , 2003, Journal of cellular biochemistry.
[64] John D Lambris,et al. Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1. , 2003, Blood.
[65] H. Broxmeyer,et al. Stromal cell‐derived factor‐1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and Gαi proteins and enhances engraftment of competitive, repopulating stem cells , 2003, Journal of leukocyte biology.
[66] R. Gorlin,et al. Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease , 2003, Nature Genetics.
[67] M. Ratajczak,et al. Expression of Functional CXCR4 by Muscle Satellite Cells and Secretion of SDF‐1 by Muscle‐Derived Fibroblasts is Associated with the Presence of Both Muscle Progenitors in Bone Marrow and Hematopoietic Stem/Progenitor Cells in Muscles , 2003, Stem cells.
[68] X. Qian,et al. SDF-1α production is negatively regulated by mouse estrogen enhanced transcript in a mouse thymus epithelial cell line , 2003 .
[69] K. Korach,et al. Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. , 2003, Molecular endocrinology.
[70] P. Casanova,et al. Role of the α‐chemokine stromal cell‐derived factor (SDF‐1) in the developing and mature central nervous system , 2003 .
[71] R. Bonavia,et al. Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. , 2003, Cancer research.
[72] Y. Matsui,et al. Impaired colonization of the gonads by primordial germ cells in mice lacking a chemokine, stromal cell-derived factor-1 (SDF-1) , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[73] R. Bonavia,et al. Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation. , 2003, Toxicology letters.
[74] S. Stier,et al. Stromal cell‐derived factor 1α (SDF‐1α) induces gene‐expression of early growth response‐1 (Egr‐1) and VEGF in human arterial endothelial cells and enhances VEGF induced cell proliferation , 2003, Cell proliferation.
[75] Takashi Uchiyama,et al. Natural Alpha Interferon-Producing Cells Respond to Human Immunodeficiency Virus Type 1 with Alpha Interferon Production and Maturation into Dendritic Cells , 2003, Journal of Virology.
[76] R. Ganju,et al. Differential Regulation of CXCR4-mediated T-cell Chemotaxis and Mitogen-activated Protein Kinase Activation by the Membrane Tyrosine Phosphatase, CD45* , 2003, The Journal of Biological Chemistry.
[77] J. Isner,et al. Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization , 2003, Circulation.
[78] A. Schier. Chemokine Signaling: Rules of Attraction , 2003, Current Biology.
[79] M. Ratajczak,et al. CXCR4–SDF-1 Signalling, Locomotion, Chemotaxis and Adhesion , 2003, Journal of Molecular Histology.
[80] G. Eckert,et al. Statin effects on cholesterol micro-domains in brain plasma membranes. , 2003, Biochemical pharmacology.
[81] H. Blau,et al. Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[82] V. Robert-Hebmann,et al. Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling. , 2003, Blood.
[83] H. Broxmeyer,et al. Transgenic Expression of Stromal Cell-Derived Factor-1/CXC Chemokine Ligand 12 Enhances Myeloid Progenitor Cell Survival/Antiapoptosis In Vitro in Response to Growth Factor Withdrawal and Enhances Myelopoiesis In Vivo , 2003, The Journal of Immunology.
[84] V. Wee Yong,et al. CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival* , 2002, The Journal of Biological Chemistry.
[85] R. Bachelder,et al. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. , 2002, Cancer research.
[86] H. Broxmeyer,et al. Cell Surface Peptidase CD26/Dipeptidylpeptidase IV Regulates CXCL12/Stromal Cell-Derived Factor-1α-Mediated Chemotaxis of Human Cord Blood CD34+ Progenitor Cells1 , 2002, The Journal of Immunology.
[87] Helen M. Blau,et al. Biological Progression from Adult Bone Marrow to Mononucleate Muscle Stem Cell to Multinucleate Muscle Fiber in Response to Injury , 2002, Cell.
[88] Timothy Gomez,et al. G Protein-Coupled Chemokine Receptors Induce Both Survival and Apoptotic Signaling Pathways1 , 2002, The Journal of Immunology.
[89] Oana A. Tomescu,et al. CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion. , 2002, Blood.
[90] M. Ratajczak,et al. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. , 2002, Blood.
[91] O. Kollet,et al. The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2mnull mice , 2002, Leukemia.
[92] M. Tessier-Lavigne,et al. The chemokine SDF1 regulates migration of dentate granule cells. , 2002, Development.
[93] I. Petit,et al. Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. , 2002, Experimental hematology.
[94] M. Farzan,et al. The Role of Post-translational Modifications of the CXCR4 Amino Terminus in Stromal-derived Factor 1α Association and HIV-1 Entry* , 2002, The Journal of Biological Chemistry.
[95] J. Broach,et al. A Point Mutation That Confers Constitutive Activity to CXCR4 Reveals That T140 Is an Inverse Agonist and That AMD3100 and ALX40-4C Are Weak Partial Agonists* , 2002, The Journal of Biological Chemistry.
[96] R. Taichman,et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4 , 2002, Nature Immunology.
[97] F. Jirik,et al. Disruption of a Single Pten Allele Augments the Chemotactic Response of B Lymphocytes to Stromal Cell-Derived Factor-11 , 2002, The Journal of Immunology.
[98] D. Leduc,et al. Leukocyte Elastase Negatively Regulates Stromal Cell-derived Factor-1 (SDF-1)/CXCR4 Binding and Functions by Amino-terminal Processing of SDF-1 and CXCR4* , 2002, The Journal of Biological Chemistry.
[99] M. Probst-Kepper,et al. CXCR4/CXCL12 expression and signalling in kidney cancer , 2002, British Journal of Cancer.
[100] D. Scadden,et al. Thymocyte emigration is mediated by active movement away from stroma-derived factors. , 2002, The Journal of clinical investigation.
[101] Evan T Keller,et al. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. , 2002, Cancer research.
[102] M. Le Bousse-Kerdilès,et al. Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. , 2002, Blood.
[103] J. Isner,et al. Endothelial Progenitor Cell Vascular Endothelial Growth Factor Gene Transfer for Vascular Regeneration , 2002, Circulation.
[104] R. Alon,et al. TGF‐β1 enhances SDF‐1α‐induced chemotaxis and homing of naive T cells by up‐regulating CXCR4 expression and downstream cytoskeletal effector molecules , 2002, European journal of immunology.
[105] J. Isner,et al. Bone Marrow as a Source of Endothelial Cells for Natural and Iatrogenic Vascular Repair , 2001, Annals of the New York Academy of Sciences.
[106] M. Ratajczak,et al. Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment. , 2001, Blood.
[107] I. Weissman,et al. Stem cells, cancer, and cancer stem cells , 2001, Nature.
[108] Gideon Rechavi,et al. A Possible Role for CXCR4 and Its Ligand, the CXC Chemokine Stromal Cell-Derived Factor-1, in the Development of Bone Marrow Metastases in Neuroblastoma1 , 2001, The Journal of Immunology.
[109] F. Barr. Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma , 2001, Oncogene.
[110] M. Ratajczak,et al. The SDF‐1‐CXCR4 Axis Stimulates VEGF Secretion and Activates Integrins but does not Affect Proliferation and Survival in Lymphohematopoietic Cells , 2001, Stem cells.
[111] Kazuhiko Yamamoto,et al. Chemokine receptors in human basophils: inducible expression of functional CXCR4 , 2001, Journal of leukocyte biology.
[112] J. Groopman,et al. Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. , 2001, Blood.
[113] S. Rafii,et al. Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. , 2001, Blood.
[114] K. Satomura,et al. Circulating Skeletal Stem Cells , 2001, The Journal of cell biology.
[115] M. Ratajczak,et al. Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. , 2001, Blood.
[116] David A. Williams,et al. Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[117] T. Mcclanahan,et al. Involvement of chemokine receptors in breast cancer metastasis , 2001, Nature.
[118] F. Prósper,et al. Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells. , 2001, Experimental hematology.
[119] R. Ganju,et al. SHP2 and cbl participate in alpha-chemokine receptor CXCR4-mediated signaling pathways. , 2001, Blood.
[120] D. Kelvin,et al. The human hematopoietic stem cell compartment is heterogeneous for CXCR4 expression. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[121] M. Ratajczak,et al. Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis. , 2000, Blood.
[122] R. Taichman,et al. Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function. , 2000, The Journal of clinical investigation.
[123] M. Ratajczak,et al. Differential MMP and TIMP production by human marrow and peripheral blood CD34(+) cells in response to chemokines. , 2000, Experimental hematology.
[124] J. Forrester,et al. CXCR4 Receptor Expression on Human Retinal Pigment Epithelial Cells from the Blood-Retina Barrier Leads to Chemokine Secretion and Migration in Response to Stromal Cell-Derived Factor 1α1 , 2000, The Journal of Immunology.
[125] G. Christensen,et al. Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure. , 2000, Cardiovascular research.
[126] I. Clark-lewis,et al. Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. , 2000 .
[127] H. Yssel,et al. Cytokines and Cell Surface Molecules Independently Induce CXCR4 Expression on CD4+ CCR7+ Human Memory T Cells1 , 2000, The Journal of Immunology.
[128] Rebekah Gardner,et al. Liver from bone marrow in humans , 2000, Hepatology.
[129] R. Alon,et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. , 2000, Blood.
[130] J. Groopman,et al. Stromal cell-derived factor-1 a stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells : roles of phosphoinositide-3 kinase and protein kinase C , 2000 .
[131] M. Ratajczak,et al. Binding of stromal derived factor‐1α(SDF‐1α) to CXCR4 chemokine receptorin normal human megakaryoblasts butnot in platelets induces phosphorylationof mitogen‐activated protein kinase p42/44 (MAPK), ELK‐1 transcription factor and serine/threonine kinase AKT , 2000, European journal of haematology.
[132] S. Rafii,et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. , 2000, Blood.
[133] A. Zlotnik,et al. Chemokines: a new classification system and their role in immunity. , 2000, Immunity.
[134] Yue Sun,et al. β-Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This Implicates Multiple Interaction Sites between β-Arrestin and CXCR4* , 2000, The Journal of Biological Chemistry.
[135] J. Westwick,et al. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. , 1999, Journal of immunology.
[136] C. Martínez-A,et al. The chemokine SDF‐lα triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[137] J. Isner,et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. , 1999, Circulation research.
[138] Hiroshi Takahashi,et al. Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon , 1999, Nature Medicine.
[139] T. Springer,et al. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. , 1999, Immunity.
[140] Haruchika Masuda,et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization , 1999, Nature Medicine.
[141] R. Alon,et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. , 1999, Science.
[142] H. Broxmeyer,et al. Chemokines: signal lamps for trafficking of T and B cells for development and effector function , 1999, Journal of leukocyte biology.
[143] R. Ganju,et al. The α-Chemokine, Stromal Cell-derived Factor-1α, Binds to the Transmembrane G-protein-coupled CXCR-4 Receptor and Activates Multiple Signal Transduction Pathways* , 1998, The Journal of Biological Chemistry.
[144] R. Bronson,et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[145] S. Rafii,et al. Evidence for circulating bone marrow-derived endothelial cells. , 1998, Blood.
[146] Masahiko Kuroda,et al. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development , 1998, Nature.
[147] Kouji Matsushima,et al. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract , 1998, Nature.
[148] R. Snyderman,et al. Regulation of Human Chemokine Receptors CXCR4 , 1997, The Journal of Biological Chemistry.
[149] Z. Lu,et al. Activation of HIV-1 Coreceptor (CXCR4) Mediates Myelosuppression* , 1997, The Journal of Biological Chemistry.
[150] T. Springer,et al. The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood , 1997, The Journal of experimental medicine.
[151] S. Nishikawa,et al. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1 , 1996, Nature.
[152] J. Dick,et al. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. , 1992, Science.
[153] Z. Brown,et al. Chemokine Receptors , 2006, Treatments in respiratory medicine.
[154] M. Ratajczak,et al. Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient. , 2005, Blood.
[155] R. Alon,et al. Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. , 2005, The Journal of clinical investigation.
[156] R. Willemze,et al. Reduced stem cell mobilization in mice receiving antibiotic modulation of the intestinal flora: involvement of endotoxins as cofactors in mobilization. , 2004, Blood.
[157] M. Ratajczak,et al. Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury. , 2004, Blood cells, molecules & diseases.
[158] M. Ratajczak,et al. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells ‘hide out’ in the bone marrow , 2004, Leukemia.
[159] M. Ratajczak,et al. Heterogeneous populations of bone marrow stem cells--are we spotting on the same cells from the different angles? , 2004, Folia histochemica et cytobiologica.
[160] S. Rafii,et al. Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis , 2004, Nature Medicine.
[161] R. Hershkoviz,et al. Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis. , 2003, International immunology.
[162] M. Ratajczak,et al. Circulating CXCR4-positive stem/progenitor cells compete for SDF-1-positive niches in bone marrow, muscle and neural tissues: an alternative hypothesis to stem cell plasticity. , 2003, Folia histochemica et cytobiologica.
[163] Kelvin K. W. Chan,et al. The statins as anticancer agents. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[164] P. Casanova,et al. Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. , 2003, Glia.
[165] X. Qian,et al. SDF-1alpha production is negatively regulated by mouse estrogen enhanced transcript in a mouse thymus epithelial cell line. , 2003, Cellular immunology.
[166] M. Valk,et al. Transplanted bone marrow generates new neurons in human brains , 2003 .
[167] B. Petersen,et al. SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. , 2002, Cloning and stem cells.
[168] S. Frisch,et al. Anoikis mechanisms. , 2001, Current opinion in cell biology.
[169] J. Rodríguez-Frade,et al. The chemokine SDF-1 (cid:97) triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway , 1999 .
[170] K. Matsushima,et al. Inhibition of immature erythroid progenitor cell proliferation by macrophage inflammatory protein-1alpha by interacting mainly with a C-C chemokine receptor, CCR1. , 1997, Blood.