A New Chemical Access for 3′‐Acetyl‐4′‐hydroxychalcones Using Borontrifluoride‐etherate via a Regioselective Claisen—Schmidt Condensation and Its Application in the Synthesis of Chalcone Hybrids.

The Claisen—Schmidt condensation of the unsymmetrical bisacetylarene (I) with various aldehydes under optimized conditions affords chalcones (III) in good yields.