A New Chemical Access for 3′‐Acetyl‐4′‐hydroxychalcones Using Borontrifluoride‐etherate via a Regioselective Claisen—Schmidt Condensation and Its Application in the Synthesis of Chalcone Hybrids.
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The Claisen—Schmidt condensation of the unsymmetrical bisacetylarene (I) with various aldehydes under optimized conditions affords chalcones (III) in good yields.