EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer

[1]  A. Shearn,et al.  The ubiquitin ligase Hyperplastic discs negatively regulates hedgehog and decapentaplegic expression by independent mechanisms , 2002, Development.

[2]  R. Sutherland,et al.  EDD, the Human Hyperplastic Discs Protein, Has a Role in Progesterone Receptor Coactivation and Potential Involvement in DNA Damage Response* , 2002, The Journal of Biological Chemistry.

[3]  M. Nakao,et al.  Cooperation of HECT-domain Ubiquitin Ligase hHYD and DNA Topoisomerase II-binding Protein for DNA Damage Response* , 2002, The Journal of Biological Chemistry.

[4]  A. Bashein,et al.  Global cDNA Amplification Combined with Real-Time RT–PCR: Accurate Quantification of Multiple Human Potassium Channel Genes at the Single Cell Level , 2000, Yeast.

[5]  C. Clarke,et al.  The hD52 (TPD52) gene is a candidate target gene for events resulting in increased 8q21 copy number in human breast carcinoma , 2000, Genes, chromosomes & cancer.

[6]  T. Visakorpi,et al.  Mapping the amplification of EIF3S3 in breast and prostate cancer , 2000, Genes, chromosomes & cancer.

[7]  D L Pincus,et al.  Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. , 1999, Genomics.

[8]  E. Prochownik,et al.  MYC oncogenes and human neoplastic disease , 1999, Oncogene.

[9]  R. Sutherland,et al.  Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs , 1998, Oncogene.

[10]  Sajeev P. Cherian,et al.  Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesis , 1998, Hepatology.

[11]  T. Godfrey,et al.  Molecular cytogenetic analysis of consistent abnormalities at 8q12‐q22 in breast cancer , 1998, Genes, chromosomes & cancer.

[12]  M. Scheffner,et al.  Characterization of Human hect Domain Family Members and Their Interaction with UbcH5 and UbcH7* , 1998, The Journal of Biological Chemistry.

[13]  A. Marchetti,et al.  The chromosome location of the human homolog of the mouse mammary tumor-associated gene INT6 and its status in human breast carcinomas. , 1997, Genomics.

[14]  M. Buendia,et al.  Comprehensive allelotyping of human hepatocellular carcinoma , 1997, Oncogene.

[15]  A. Gillenwater,et al.  Genotypic alterations in benign and malignant salivary gland tumors: histogenetic and clinical implications. , 1997, The American journal of surgical pathology.

[16]  R. Rees,et al.  Abnormalities of chromosomes 3 and 8 in posterior uveal melanoma correlate with prognosis , 1997, Genes, chromosomes & cancer.

[17]  M. Scheffner,et al.  A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[18]  B. Dutrillaux,et al.  Detection of DNA amplification in 17 primary breast carcinomas with homogeneously staining regions by a modified comparative genomic hybridization technique , 1994, Genes, chromosomes & cancer.

[19]  J Piper,et al.  Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[20]  B. Palsson,et al.  Human Cell Culture , 1999, Human Cell Culture.

[21]  G. Mann,et al.  10q deletions in metastatic cutaneous melanoma. , 1998, Cancer genetics and cytogenetics.

[22]  K. Bland,et al.  Stage I and stage II infiltrating ductal carcinoma of the breast analyzed for chromosome 8 copy number using fluorescent in situ hybridization. , 1997, Pathobiology : journal of immunopathology, molecular and cellular biology.