Detection of glucose based on bimetallic PtCu nanochains modified electrodes.

A series of novel bimetallic PtCu nanochains have been synthesized through a water-based mild chemical route, and their compositions (Pt(x)Cu(1-x)) can be conveniently tuned at the mesoscopic scale by a facile dealloying process. These nanomaterials have been characterized by transmission electron microscope (TEM), high-resolution TEM (HRTEM), X-ray powder diffraction (XRD), and elemental analysis. They have different compositions (Pt88Cu12, Pt75Cu25, and Pt50Cu50) but have similar morphology. Electrochemical activity of these nanomaterials is compared to Pt and nanochains of Pt when they are chemically modified onto a glassy carbon electrode. Electrochemical measurements demonstrate that the sensors made by these PtCu nanomaterials are very sensitive and selective for glucose detection due to the wiring of dispersed crystals, porous nanostructure, clean surface, and synergetic electronic effects of the alloyed atoms. Among them, the modified electrode made of Pt75Cu25 shows the best performance. The superior catalytic activity and selectivity make nanomaterials, via the green synthesis, very promising for applications in direct biosensing of glucose.

[1]  Sangyun Park,et al.  Nonenzymatic continuous glucose monitoring in human whole blood using electrified nanoporous Pt. , 2012, Biosensors & bioelectronics.

[2]  Yadong Li,et al.  Ultrathin Au-Ag bimetallic nanowires with Coulomb blockade effects. , 2011, Chemical communications.

[3]  Rongming Wang,et al.  Platinum catalyzed growth of NiPt hollow spheres with an ultrathin shell , 2011 .

[4]  Yu.B. Vassilyev,et al.  Kinetics and mechanism of glucose electrooxidation on different electrode-catalysts: Part I. Adsorption and oxidation on platinum , 1985 .

[5]  Yu Jin Jang,et al.  Bimetallic multifunctional core@shell plasmonic nanoparticles for localized surface plasmon resonance based sensing and electrocatalysis. , 2012, Analytical chemistry.

[6]  V. K. Rao,et al.  Immobilization of acetylcholineesterase-choline oxidase on a gold-platinum bimetallic nanoparticles modified glassy carbon electrode for the sensitive detection of organophosphate pesticides, carbamates and nerve agents. , 2009, Biosensors & bioelectronics.

[7]  J. Klett,et al.  Tuning the Basicity of Synergic Bimetallic Reagents: Switching the Regioselectivity of the Direct Dimetalation of Toluene from 2,5- to 3,5-Positions** , 2008, Angewandte Chemie.

[8]  Jiayin Yuan,et al.  In situ growth of catalytic active Au-Pt bimetallic nanorods in thermoresponsive core-shell microgels. , 2010, ACS nano.

[9]  Jinxia Xu,et al.  Polymer-supported bimetallic Ag@AgAu nanocomposites: synthesis and catalytic properties. , 2012, Chemistry, an Asian journal.

[10]  G. W. Small,et al.  Noninvasive glucose sensing. , 2005, Analytical chemistry.

[11]  N. Ashcroft,et al.  Vegard's law. , 1991, Physical review. A, Atomic, molecular, and optical physics.

[12]  Dingsheng Wang,et al.  Bimetallic Nanocrystals: Liquid‐Phase Synthesis and Catalytic Applications , 2011, Advanced materials.

[13]  Johannes E. M. N. Klein,et al.  Bimetallic palladium catalysis: direct observation of Pd(III)-Pd(III) intermediates. , 2009, Journal of the American Chemical Society.

[14]  Xiaowang Liu,et al.  Bimetallic nanoparticles: kinetic control matters. , 2012, Angewandte Chemie.

[15]  Malcolm L. H. Green,et al.  Copper oxide nanoparticle impurities are responsible for the electroanalytical detection of glucose seen using multiwalled carbon nanotubes , 2008 .

[16]  B. Beden,et al.  Fourier transform infrared reflectance spectroscopic investigation of the electrocatalytic oxidation of d-glucose: Identification of reactive intermediates and reaction products , 1996 .

[17]  Fei Xiao,et al.  Nonenzymatic glucose sensor based on ultrasonic-electrodeposition of bimetallic PtM (M=Ru, Pd and Au) nanoparticles on carbon nanotubes-ionic liquid composite film. , 2009, Biosensors & bioelectronics.

[18]  Lingling Wang,et al.  Non-enzymatic electrochemical sensing of glucose , 2013, Microchimica Acta.

[19]  Probal Banerjee,et al.  Core-shell hybrid nanogels for integration of optical temperature-sensing, targeted tumor cell imaging, and combined chemo-photothermal treatment. , 2010, Biomaterials.

[20]  G. S. Wilson,et al.  Biosensors for real-time in vivo measurements. , 2005, Biosensors & bioelectronics.

[21]  Hyunhyub Ko,et al.  Bimetallic Nanocobs: Decorating Silver Nanowires with Gold Nanoparticles , 2008 .

[22]  Moon J. Kim,et al.  Facile synthesis of bimetallic nanoplates consisting of Pd cores and Pt shells through seeded epitaxial growth. , 2008, Nano letters.

[23]  Richard G. Compton,et al.  The non-enzymatic determination of glucose using an electrolytically fabricated nickel microparticle modified boron-doped diamond electrode or nickel foil electrode , 2010 .

[24]  H. Gasteiger,et al.  Characterization of High‐Surface‐Area Electrocatalysts Using a Rotating Disk Electrode Configuration , 1998 .

[25]  R. Zengerle,et al.  Cyclic Electrodeposition of PtCu Alloy: Facile Fabrication of Highly Porous Platinum Electrodes , 2012, Advanced materials.

[26]  Sejin Park,et al.  Nonenzymatic glucose detection using mesoporous platinum. , 2003, Analytical chemistry.

[27]  S. Matsunaga,et al.  Heterobimetallic transition metal/rare earth metal bifunctional catalysis: a Cu/Sm/Schiff base complex for syn-selective catalytic asymmetric nitro-Mannich reaction. , 2010, Journal of the American Chemical Society.

[28]  Richard G. Compton,et al.  Electrochemical Non-enzymatic Glucose Sensors: A Perspective and an Evaluation , 2010, International Journal of Electrochemical Science.

[29]  Aicheng Chen,et al.  Amperometric glucose sensor based on platinum–iridium nanomaterials , 2008 .

[30]  Yong Ding,et al.  Atomic structure of Au-Pd bimetallic alloyed nanoparticles. , 2010, Journal of the American Chemical Society.

[31]  Yu Ding,et al.  A novel NiO-Au hybrid nanobelts based sensor for sensitive and selective glucose detection. , 2011, Biosensors & bioelectronics.

[32]  Kang Wang,et al.  Highly Ordered Platinum‐Nanotubule Arrays for Amperometric Glucose Sensing , 2005 .

[33]  J. Elam,et al.  Supported ru-pt bimetallic nanoparticle catalysts prepared by atomic layer deposition. , 2010, Nano letters.

[34]  Changqing Sun,et al.  Pt-Pb nanowire array electrode for enzyme-free glucose detection. , 2008, Biosensors & bioelectronics.

[35]  G. Henkelman,et al.  Au@Pt dendrimer encapsulated nanoparticles as model electrocatalysts for comparison of experiment and theory , 2012 .

[36]  Shuhong Yu,et al.  Large scale restructuring of porous Pt-Ni nanoparticle tubes for methanol oxidation: A highly reactive, stable, and restorable fuel cell catalyst , 2011 .

[37]  Adam Heller,et al.  Electrochemistry in diabetes management. , 2010, Accounts of chemical research.

[38]  Y. Lei,et al.  Preparation, characterization and application of novel conductive NiO–CdO nanofibers with dislocation feature , 2012 .

[39]  Younan Xia,et al.  Pd-Pt Bimetallic Nanodendrites with High Activity for Oxygen Reduction , 2009, Science.

[40]  Yadong Li,et al.  Highly branched Pt–Ni nanocrystals enclosed by stepped surface for methanol oxidation , 2012 .

[41]  E. Easton,et al.  PtCu/C and Pt(Cu)/C catalysts: Synthesis, characterization and catalytic activity towards ethanol electrooxidation , 2013 .

[42]  Tetsuya Osaka,et al.  Synthesis of mesoporous PtCu film modified with Ru submonolayer as catalyst for methanol electrooxidation. , 2010, Chemical communications.

[43]  Joseph Wang.  Electrochemical glucose biosensors. , 2008, Chemical reviews.

[44]  Aicheng Chen,et al.  Nonenzymatic electrochemical glucose sensor based on nanoporous PtPb networks. , 2008, Analytical chemistry.

[45]  T. Mallouk,et al.  Combinatorial discovery of alloy electrocatalysts for amperometric glucose sensors. , 2001, Analytical chemistry.

[46]  Aicheng Chen,et al.  Nanoporous Pt‐Ru Networks and Their Electrocatalytical Properties , 2007 .

[47]  P. Strasser,et al.  Size-dependent morphology of dealloyed bimetallic catalysts: linking the nano to the macro scale. , 2012, Journal of the American Chemical Society.

[48]  Yunqing Liu,et al.  Nanoporous PtAg and PtCu alloys with hollow ligaments for enhanced electrocatalysis and glucose biosensing. , 2011, Biosensors & bioelectronics.

[49]  H. Kung,et al.  Study of Supported PtCu and PdAu Bimetallic Nanoparticles Using In-Situ X-ray Tools† , 2010 .

[50]  Xiaoqing Lu,et al.  Nonenzymatic glucose voltammetric sensor based on gold nanoparticles/carbon nanotubes/ionic liquid nanocomposite. , 2009, Talanta.

[51]  Sejin Park,et al.  Electrochemical non-enzymatic glucose sensors. , 2006, Analytica chimica acta.

[52]  Arben Merkoçi,et al.  Bimetallic nanowires as electrocatalysts for nonenzymatic real-time impedancimetric detection of glucose. , 2012, Chemical communications.

[53]  Ernest Yeager,et al.  In situ infrared studies of glucose oxidation on platinum in an alkaline medium , 1991 .

[54]  Chengzhou Zhu,et al.  PdM (M = Pt, Au) Bimetallic Alloy Nanowires with Enhanced Electrocatalytic Activity for Electro‐oxidation of Small Molecules , 2012, Advanced materials.

[55]  Aicheng Chen,et al.  Platinum-based nanostructured materials: synthesis, properties, and applications. , 2010, Chemical reviews.

[56]  A. Hirata,et al.  Nanoporous PdNi Bimetallic Catalyst with Enhanced Electrocatalytic Performances for Electro‐oxidation and Oxygen Reduction Reactions , 2011 .