Effects of noise and filtering on SVD-based morphological parameters of the T wave in the ECG

Singular value decomposition (SVD) based electrocardiogram (ECG) morphology analysis is a novel method in the assessment of subtle abnormalities in the T wave morphology of 12-lead ECG. As various types of noise contaminate the ECG signal and create a bias for the morphological analyses, this study was designed to estimate the effects of noise on the SVD method in an experimental setup. Ideal signals were generated by filtering real ECG signals several times with the Savitzky-Golay filter. Random and real noise samples were superimposed on the ideal signals. The noisy signals were filtered with a power line interference filter combined with the Savitzky-Golay or the wavelet filter. Results show that noise increased both the dipolar and non-dipolar components significantly unless filtering was applied. R-TWR (relative T wave residuum) and A-TWR (absolute T wave residuum) were four to eight times higher in noisy signals. The experiments with patient data demonstrated that certain types of noise may even lead to erroneous classification of patients. Filtering brings the median values closer to the correct ones and decreases significantly the variance of the values of parameters.

[1]  Marek Malik,et al.  Practical use of T wave morphology assessment. , 2002, Cardiac electrophysiology review.

[2]  P. E. Tikkanen,et al.  Nonlinear wavelet and wavelet packet denoising of electrocardiogram signal , 1999, Biological Cybernetics.

[3]  M. Malik,et al.  Spatial, temporal and wavefront direction characteristics of 12-lead T-wave morphology , 1999, Medical & Biological Engineering & Computing.

[4]  Katerina Hnatkova,et al.  Analysis of T-Wave Morphology From the 12-Lead Electrocardiogram for Prediction of Long-Term Prognosis in Male US Veterans , 2002, Circulation.

[5]  Pauli Tikkanen,et al.  Characterization and application of analysis methods for ECG and time interval variability data , 1999 .

[6]  S. Hohnloser,et al.  Assessment of QT dispersion for prediction of mortality or arrhythmic events after myocardial infarction: results of a prospective, long-term follow-up study. , 1998, Circulation.

[7]  Katerina Hnatkova,et al.  Repolarization Abnormality for Prediction of All‐Cause and Cardiovascular Mortality in American Indians: The Strong Heart Study , 2005, Journal of cardiovascular electrophysiology.

[8]  Katerina Hnatkova,et al.  Ventricular gradient and nondipolar repolarization components increase at higher heart rate. , 2004, American journal of physiology. Heart and circulatory physiology.

[9]  Qiuzhen Xue,et al.  New algorithms for QT dispersion analysis , 1996, Computers in Cardiology 1996.

[10]  L. Horan,et al.  A rapid assay of dipolar and extradipolar content in the human electrocardiogram. , 1972, Journal of electrocardiology.

[11]  Katerina Hnatkova,et al.  Sex differences in repolarization homogeneity and its circadian pattern. , 2002, American journal of physiology. Heart and circulatory physiology.

[12]  J.P. Marques de Sa,et al.  ECG noise filtering using wavelets with soft-thresholding methods , 1999, Computers in Cardiology 1999. Vol.26 (Cat. No.99CH37004).

[13]  Joos Vandewalle,et al.  Two Methods for Optimal MECG Elimination and FECG Detection from Skin Electrode Signals , 1987, IEEE Transactions on Biomedical Engineering.

[14]  Richard B. Devereux,et al.  Principal Component Analysis of the T Wave and Prediction of Cardiovascular Mortality in American Indians: The Strong Heart Study , 2002, Circulation.

[15]  Mariana Moga,et al.  Wavelets as methods for ECG signal processing. , 2004, Romanian journal of internal medicine = Revue roumaine de medecine interne.

[16]  M Malik,et al.  Predictive value of T-wave morphology variables and QT dispersion for postmyocardial infarction risk assessment. , 2001, Journal of electrocardiology.

[17]  Mariana Moga,et al.  Frequency domain and wavelets applications as methods for ECG signal processing. , 2002, Studies in health technology and informatics.

[18]  M Malik,et al.  Analysis of 12-Lead T-Wave Morphology for Risk Stratification After Myocardial Infarction , 2000, Circulation.

[19]  H. Koymen,et al.  SVD-based on-line exercise ECG signal orthogonalization , 1999, IEEE Transactions on Biomedical Engineering.

[20]  A J Camm,et al.  QT Dispersion Does Not Represent Electrocardiographic Interlead Heterogeneity of Ventricular Repolarization , 2000, Journal of cardiovascular electrophysiology.

[21]  E. Prystowsky,et al.  State of the Journal 2004 , 2005 .

[22]  Hans Lohninger,et al.  Teach/Me - Data Analysis , 1999 .

[23]  E FRANK Absolute Quantitative Comparison of Instantaneous QRS Equipotentials on a Normal Subject with Dipole Potentials on a Homogeneous Torso Model , 1955, Circulation research.