Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

[1]  A. Rudensky,et al.  An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses , 2017, Nature Communications.

[2]  A. Kriegel,et al.  MiR-146a/b: a family with shared seeds and different roots. , 2017, Physiological genomics.

[3]  P. M. Davis,et al.  B cells from African American lupus patients exhibit an activated phenotype. , 2016, JCI insight.

[4]  Z. Rahman,et al.  IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity , 2016, The Journal of experimental medicine.

[5]  U. Klein,et al.  Unexpected functions of nuclear factor-&kgr;B during germinal center B-cell development: implications for lymphomagenesis , 2015, Current opinion in hematology.

[6]  R. Casellas,et al.  MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres , 2015, Nature Communications.

[7]  S. Booth,et al.  MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response , 2014, Front. Immunol..

[8]  Margaret Alexander,et al.  miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. , 2014, Immunity.

[9]  Hai Qi,et al.  T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction , 2014, Nature.

[10]  U. Klein,et al.  Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits , 2014, The Journal of experimental medicine.

[11]  S. Ghosh,et al.  Regulation of NF-κB by TNF family cytokines. , 2014, Seminars in immunology.

[12]  John M. Lindner,et al.  Cutting Edge: The Transcription Factor Bob1 Counteracts B Cell Activation and Regulates miR-146a in B Cells , 2014, The Journal of Immunology.

[13]  F. Sallusto,et al.  Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype. , 2013, Immunity.

[14]  A. DeFranco,et al.  Contribution of Toll‐like receptor signaling to germinal center antibody responses , 2012, Immunological reviews.

[15]  R. Xavier,et al.  Regulation of monocyte functional heterogeneity by miR-146a and Relb. , 2012, Cell reports.

[16]  D. Kitamura,et al.  In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo. , 2011, Nature communications.

[17]  Nan Shen,et al.  A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus , 2011, PLoS genetics.

[18]  Ryan M. O’Connell,et al.  NF-κB dysregulation in microRNA-146a–deficient mice drives the development of myeloid malignancies , 2011, Proceedings of the National Academy of Sciences.

[19]  P. Linsley,et al.  miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice , 2011, The Journal of experimental medicine.

[20]  S. Monticelli,et al.  MiR-146a in Immunity and Disease , 2011, Molecular biology international.

[21]  S. Crotty,et al.  Follicular helper CD4 T cells (TFH). , 2011, Annual review of immunology.

[22]  J. Cerhan,et al.  A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling , 2010, The Journal of experimental medicine.

[23]  Ryan M. O’Connell,et al.  MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. , 2010, Immunity.

[24]  David Baltimore,et al.  Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses , 2010, Cell.

[25]  Lai Wei,et al.  Regulation of microRNA expression and abundance during lymphopoiesis. , 2010, Immunity.

[26]  C. Glass,et al.  Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.

[27]  R. Noelle,et al.  Molecular mechanism and function of CD40/CD40L engagement in the immune system , 2009, Immunological reviews.

[28]  P. Tak,et al.  MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. , 2009, Arthritis and rheumatism.

[29]  A. Baldwin,et al.  NF-κB pathways in the immune system: control of the germinal center reaction , 2008, Immunologic research.

[30]  W. Cook,et al.  The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation. , 2007, Blood.

[31]  G. Sonenshein,et al.  CD40 Ligand-mediated Activation of the de Novo RelB NF-κB Synthesis Pathway in Transformed B Cells Promotes Rescue from Apoptosis* , 2007, Journal of Biological Chemistry.

[32]  D. Baltimore,et al.  NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses , 2006, Proceedings of the National Academy of Sciences.

[33]  Xuejun Jiang,et al.  Internalization of CD40 regulates its signal transduction in vascular endothelial cells. , 2006, Biochemical and biophysical research communications.

[34]  K. Rajewsky,et al.  Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[35]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Chris Sander,et al.  MicroRNA profiling of the murine hematopoietic system , 2005, Genome Biology.

[37]  C. Burge,et al.  Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.

[38]  A. Singer,et al.  CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 , 2005, Nature Immunology.

[39]  Y. Tu,et al.  Cattoretti and Riccardo Dalla-favera Tracking Cd40 Signaling during Germinal Center Development , 2022 .

[40]  Richard H. Scheuermann,et al.  Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands1 , 2004, The Journal of Immunology.

[41]  N. Rajewsky,et al.  Survival of Resting Mature B Lymphocytes Depends on BCR Signaling via the Igα/β Heterodimer , 2004, Cell.

[42]  P. Lipsky,et al.  Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. , 2003, The Journal of clinical investigation.

[43]  M. Daly,et al.  PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.

[44]  Mark Coles,et al.  Transgenic mice with hematopoietic and lymphoid specific expression of Cre , 2003, European journal of immunology.

[45]  C. Ahonen,et al.  The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells , 2002, Nature Immunology.

[46]  W. M. Weaver,et al.  A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. , 2001, Immunity.

[47]  T. Honjo,et al.  Human genetic defects in class-switch recombination (hyper-IgM syndromes). , 2001, Current opinion in immunology.

[48]  S. Akira,et al.  Iκb Kinase α Is Essential for Mature B Cell Development and Function , 2001, The Journal of experimental medicine.

[49]  R. Thomas,et al.  RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[50]  J. Sprent,et al.  Homeostatic T Cell Proliferation , 2000, The Journal of experimental medicine.

[51]  V. Dixit,et al.  Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity , 2000, Nature Immunology.

[52]  N. Yoshida,et al.  The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. , 1994, Immunity.

[53]  J. Sprent,et al.  T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. , 1987, Journal of immunology.

[54]  D. Calado,et al.  Germinal Centers , 2017, Methods in Molecular Biology.

[55]  Thomas R. Gingeras,et al.  STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..

[56]  M. Nussenzweig,et al.  Dopamine in germinal centers , 2017, Nature Immunology.

[57]  Riccardo Dalla-Favera,et al.  Germinal centres: role in B-cell physiology and malignancy , 2008, Nature Reviews Immunology.

[58]  N. Rajewsky,et al.  Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer. , 2004, Cell.

[59]  W. Leonard,et al.  Jaks and STATs: biological implications. , 1998, Annual review of immunology.