Does left ventricular shape influence clinical outcome in heart failure?

Background: Left ventricular (LV) shape tends to become spherical in patients with dilated cardiomyopathy of diverse etiology. Clinical and echocardiographic factors which affect the degree of LV spherical distortion and the impact of altered LV shape on prognosis have not been studied adequately.

[1]  P. Armstrong,et al.  Sequential echocardiographic-Doppler assessment of left ventricular remodelling and mitral regurgitation during evolving experimental heart failure. , 1991, Cardiovascular research.

[2]  M. LeWinter,et al.  Relation between left ventricular shape and exercise capacity in patients with left ventricular dysfunction. , 1993, Journal of the American College of Cardiology.

[3]  N. Reichek,et al.  Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. , 1986, The American journal of cardiology.

[4]  J. Carroll,et al.  Physiologic mechanisms governing hemodynamic responses to positive inotropic therapy in patients with dilated cardiomyopathy. , 1988, Circulation.

[5]  C. Tomlinson.  Left ventricular geometry and function in experimental heart failure. , 1987, The Canadian journal of cardiology.

[6]  C. Visser,et al.  Pathogenesis of mitral regurgitation in acute myocardial infarction: importance of changes in left ventricular shape and regional function. , 1996, American heart journal.

[7]  N. Smedira,et al.  Partial left ventriculectomy and mitral valve repair for end-stage congestive heart failure. , 1998, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[8]  W. Laskey,et al.  Left ventricular mechanics in dilated cardiomyopathy. , 1984, The American journal of cardiology.

[9]  F. Khaja,et al.  Left ventricular shape as a determinant of functional mitral regurgitation in patients with severe heart failure secondary to either coronary artery disease or idiopathic dilated cardiomyopathy. , 1991, The American journal of cardiology.

[10]  N. Schiller,et al.  Two-dimensional echocardiographic determination of left ventricular volume, systolic function, and mass. Summary and discussion of the 1989 recommendations of the American Society of Echocardiography. , 1991, Circulation.

[11]  M. Quiñones,et al.  Relation of ventricular size and function to heart failure status and ventricular dysrhythmia in patients with severe left ventricular dysfunction. , 1996, The American journal of cardiology.

[12]  N. Nanda,et al.  Evaluation of valvular regurgitation by color Doppler. , 1989, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[13]  J. Cohn.  Critical review of heart failure: The role of left ventricular remodeling in the therapeutic response–Cohn: Remodeling in heart failure , 1995, Clinical cardiology.

[14]  F. Pileggi,et al.  Effects of Dynamic Cardiomyoplasty on Regional Wall Motion, Ejection Fraction, and Geometry of Left Ventricle , 1992, Circulation.

[15]  N Reichek,et al.  Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy. , 1989, Journal of the American College of Cardiology.

[16]  M E King,et al.  The effects of right ventricular hemodynamics on left ventricular configuration. , 1990, The Canadian journal of cardiology.

[17]  S. Goldstein,et al.  Left ventricular shape is the primary determinant of functional mitral regurgitation in heart failure. , 1992, Journal of the American College of Cardiology.

[18]  S. Goldstein,et al.  Ventricular Remodeling and Angiotensin‐Converting Enzyme Inhibitors , 1994, Journal of cardiovascular pharmacology.

[19]  S. Shroff,et al.  Differences in the shape of the normal, cardiomyopathic, and volume overloaded human left ventricle. , 1989, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[20]  G. Lamas,et al.  Effects of left ventricular shape and captopril therapy on exercise capacity after anterior wall acute myocardial infarction. , 1989, The American journal of cardiology.

[21]  S. Goldstein,et al.  Left ventricular shape: a factor in the etiology of functional mitral regurgitation in heart failure. , 1992, American heart journal.

[22]  N Reichek,et al.  Echocardiographic Determination of Left Ventricular Mass in Man: Anatomic Validation of the Method , 1977, Circulation.

[23]  G. Lamas,et al.  Clinical significance of mitral regurgitation after acute myocardial infarction. Survival and Ventricular Enlargement Investigators. , 1997, Circulation.