Mast-Cell-Releasing Tryptase Triggers Acute Lung Injury Induced by Small Intestinal Ischemia–Reperfusion by Activating PAR-2 in Rats

[1]  G. Tsokos,et al.  A novel inhibitor of the alternative pathway of complement attenuates intestinal ischemia/reperfusion-induced injury. , 2011, The Journal of surgical research.

[2]  T. Yoshikawa,et al.  Proinflammatory role of protease-activated receptor-2 in intestinal ischemia/reperfusion injury in rats. , 2010, Molecular medicine reports.

[3]  J. Gordon,et al.  A novel ELR-CXC chemokine antagonist reduces intestinal ischemia reperfusion-induced mortality, and local and remote organ injury. , 2010, The Journal of surgical research.

[4]  C. Cámara-Lemarroy,et al.  Effects of thalidomide and pentoxyphylline over local and remote organ injury after intestinal ischemia/reperfusion. , 2010, Transplantation proceedings.

[5]  E. Oztaş,et al.  Melatonin and 1400 W ameliorate both intestinal and remote organ injury following mesenteric ischemia/reperfusion. , 2009, The Journal of surgical research.

[6]  T. Allen,et al.  Anti-chemokine autoantibody:chemokine immune complexes activate endothelial cells via IgG receptors. , 2009, American journal of respiratory cell and molecular biology.

[7]  M. Matthay,et al.  Role of Protease Activated Receptor 2 in Experimental Acute Lung Injury and Lung Fibrosis , 2009, Anatomical record.

[8]  W. Jeon,et al.  Bovine colostrum prevents bacterial translocation in an intestinal ischemia/reperfusion-injured rat model. , 2009, Journal of medicinal food.

[9]  C. Roussos,et al.  Hypoxemic resuscitation prevents pulmonary capillary endothelial dysfunction induced by normoxemic resuscitation from hemorrhagic shock , 2009, Critical care medicine.

[10]  R. Feinman,et al.  Trauma-hemorrhagic shock-induced pulmonary epithelial and endothelial cell injury utilizes different programmed cell death signaling pathways. , 2009, American journal of physiology. Lung cellular and molecular physiology.

[11]  A. Kawabata,et al.  Proteinase-Activated Receptor-2–Triggered Prostaglandin E2 Release, but Not Cyclooxygenase-2 Upregulation, Requires Activation of the Phosphatidylinositol 3–Kinase / Akt / Nuclear Factor-κB Pathway in Human Alveolar Epithelial Cells , 2009 .

[12]  A. Kawabata,et al.  Proteinase-activated receptor-2-triggered prostaglandin E(2) release, but not cyclooxygenase-2 upregulation, requires activation of the phosphatidylinositol 3-kinase/Akt / nuclear factor-kappaB pathway in human alveolar epithelial cells. , 2009, Journal of pharmacological sciences.

[13]  A. Kawabata,et al.  PAR2 triggers IL-8 release via MEK/ERK and PI3-kinase/Akt pathways in GI epithelial cells. , 2008, Biochemical and biophysical research communications.

[14]  J. Whitsett,et al.  Pulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 gene. , 2008, American journal of respiratory cell and molecular biology.

[15]  W. Jing,et al.  Influence of Ketotifen, Cromolyn Sodium, and Compound 48/80 on the survival rates after intestinal ischemia reperfusion injury in rats , 2008, BMC Gastroenterology.

[16]  I. Wicks,et al.  The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis. , 2008, Arthritis and rheumatism.

[17]  A. Knox,et al.  Beta-tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2-independent mechanism. , 2008, American journal of respiratory cell and molecular biology.

[18]  N. Vergnolle,et al.  Protease Signaling to G Protein-Coupled Receptors: Implications for Inflammation and Pain , 2008 .

[19]  N. Vergnolle,et al.  Protease signaling to G protein-coupled receptors: implications for inflammation and pain. , 2008, Journal of receptor and signal transduction research.

[20]  G. Reiser,et al.  PAR-2 activation and LPS synergistically enhance inflammatory signaling in airway epithelial cells by raising PAR expression level and interleukin-8 release. , 2007, American journal of physiology. Lung cellular and molecular physiology.

[21]  G. Caughey.  Mast cell tryptases and chymases in inflammation and host defense , 2007, Immunological reviews.

[22]  C. Brightling,et al.  Mast cells express IL‐13Rα1: IL‐13 promotes human lung mast cell proliferation and FcɛRI expression , 2006, Allergy.

[23]  Shaoheng He,et al.  Induction of lactoferrin and IL‐8 release from human neutrophils by tryptic enzymes via proteinase activated receptor‐2 , 2006, Cell biology international.

[24]  L. Kay,et al.  Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulation , 2006, British journal of pharmacology.

[25]  Y. Naito,et al.  Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis , 2006, Scandinavian journal of gastroenterology.

[26]  Shaoheng He,et al.  Induction of release and up-regulated gene expression of interleukin (IL)-8 in A549 cells by serine proteinases , 2006, BMC Cell Biology.

[27]  M. Creer,et al.  Potential role for mast cell tryptase in recruitment of inflammatory cells to endothelium. , 2005, American journal of physiology. Cell physiology.

[28]  Hua Xie,et al.  Modulation of tryptase release from human tonsil mast cells by protease inhibitors. , 2005, Pharmacological reports : PR.

[29]  Y. Itoh,et al.  Physiology and pathophysiology of proteinase-activated receptors (PARs): role of tryptase/PAR-2 in vascular endothelial barrier function. , 2005, Journal of pharmacological sciences.

[30]  B. Widegren,et al.  Influence of Mast Cells on the Expression of Adhesion Molecules on Circulating and Migrating Leukocytes in Acute Pancreatitis-Associated Lung Injury , 2005, Lung.

[31]  C. Burger,et al.  Acute mesenteric ischemia: a clinical review. , 2004, Archives of internal medicine.

[32]  G. Stewart,et al.  Role of protease-activated receptors in airway function: a target for therapeutic intervention? , 2002, Pharmacology & therapeutics.

[33]  M. Oz,et al.  Effects of mast cell membrane stabilizing agents in a rat lung ischemia-reperfusion model. , 2000, The Annals of thoracic surgery.

[34]  A. Ishizaka,et al.  Importance of interleukin-8 in the development of reexpansion lung injury in rabbits. , 2000, American journal of respiratory and critical care medicine.

[35]  A. Saluja,et al.  Effect of recombinant platelet-activating factor acetylhydrolase on two models of experimental acute pancreatitis. , 1998, Gastroenterology.

[36]  E. Chi,et al.  Lung mast cells increase in number and degranulate during pulmonary artery occlusion/reperfusion injury in dogs. , 1993, The American review of respiratory disease.