DOCTORAL SCHOOL IN ONCOLOGY AND GENETICS

[1]  W. Hahn,et al.  CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation. , 2010, Molecular endocrinology.

[2]  Duane D. Miller,et al.  Discovery and mechanistic characterization of a novel selective nuclear androgen receptor exporter for the treatment of prostate cancer. , 2010, Cancer research.

[3]  S. Balk,et al.  Androgen Receptor Phosphorylation and Activity Are Regulated by an Association with Protein Phosphatase 1* , 2009, The Journal of Biological Chemistry.

[4]  F. S. French,et al.  Site-specific Androgen Receptor Serine Phosphorylation Linked to Epidermal Growth Factor-dependent Growth of Castration-recurrent Prostate Cancer* , 2008, Journal of Biological Chemistry.

[5]  Xiao Zhen Zhou,et al.  The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease , 2007, Nature Reviews Molecular Cell Biology.

[6]  Hanzhou Wang,et al.  Cyclin D3/CDK11p58 Complex Is Involved in the Repression of Androgen Receptor , 2007, Molecular and Cellular Biology.

[7]  K. Fischbeck,et al.  Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity. , 2007, Human molecular genetics.

[8]  Elisabeth S Yeh,et al.  PIN1, the cell cycle and cancer , 2007, Nature Reviews Cancer.

[9]  M. Barbacid,et al.  Cell cycle kinases in cancer. , 2007, Current opinion in genetics & development.

[10]  G. Bubley,et al.  Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1 , 2006, Proceedings of the National Academy of Sciences.

[11]  G. Bartsch,et al.  Androgen axis in prostate cancer , 2006, Journal of cellular biochemistry.

[12]  W. Gerald,et al.  Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression. , 2006, Urology.

[13]  Zhiyong Guo,et al.  Regulation of androgen receptor activity by tyrosine phosphorylation. , 2006, Cancer cell.

[14]  P. Sicinski,et al.  Targeting Cyclins and Cyclin-Dependent Kinases in Cancer: Lessons from Mice, Hopes for Therapeutic Applications in Humans , 2006, Cell cycle.

[15]  B. E. Black,et al.  Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization. , 2006, Molecular endocrinology.

[16]  Mark A. Rubin,et al.  Activation of β-Catenin Signaling in Prostate Cancer by Peptidyl-Prolyl Isomerase Pin1-Mediated Abrogation of the Androgen Receptor-β-Catenin Interaction , 2006, Molecular and Cellular Biology.

[17]  J. Melamed,et al.  Cell-specific Regulation of Androgen Receptor Phosphorylation in Vivo* , 2005, Journal of Biological Chemistry.

[18]  Scott A. Busby,et al.  Simian Virus 40 Small t Antigen Mediates Conformation-Dependent Transfer of Protein Phosphatase 2A onto the Androgen Receptor , 2005, Molecular and Cellular Biology.

[19]  J. Trapman,et al.  Phosphorylation of androgen receptor isoforms. , 2004, The Biochemical journal.

[20]  Anna Frolov,et al.  The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer. , 2003, Cancer research.

[21]  M. Menon,et al.  Synchronized prostate cancer cells for studying androgen regulated events in cell cycle progression from G1 into S phase , 2003, Journal of cellular physiology.

[22]  E. Bissonette,et al.  Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells. , 2003, Cancer research.

[23]  Chawnshang Chang,et al.  Molecular communication between androgen receptor and general transcription machinery , 2003, The Journal of Steroid Biochemistry and Molecular Biology.

[24]  J. Shabanowitz,et al.  Androgen Receptor Phosphorylation , 2002, The Journal of Biological Chemistry.

[25]  S. Fuqua,et al.  Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function , 2002, Molecular and Cellular Biology.

[26]  K. Knudsen,et al.  Cyclin D1: Mechanism and Consequence of Androgen Receptor Co-repressor Activity* , 2002, The Journal of Biological Chemistry.

[27]  D. Feldman,et al.  The development of androgen-independent prostate cancer , 2001, Nature Reviews Cancer.

[28]  Tianhua Niu,et al.  Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c‐Jun towards cyclin D1 , 2001, The EMBO journal.

[29]  R. Becklin,et al.  Identification of a novel phosphorylation site in human androgen receptor by mass spectrometry. , 2001, Biochemical and biophysical research communications.

[30]  T. Hunter,et al.  Oncogenic kinase signalling , 2001, Nature.

[31]  H. Scher,et al.  Collocation of androgen receptor gene mutations in prostate cancer. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[32]  J. Palvimo,et al.  Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[33]  K. Makino,et al.  HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. , 2000, Cancer research.

[34]  M. Shen,et al.  Molecular genetics of prostate cancer. , 2000, Genes & development.

[35]  I. Melezínek,et al.  The role of prostate specific antigen measurement in the detection and management of prostate cancer. , 2000, Endocrine-related cancer.

[36]  M. Kirschner,et al.  Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. , 1997, Science.

[37]  J Isola,et al.  Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. , 1997, Cancer research.

[38]  T. Hunter,et al.  A human peptidyl–prolyl isomerase essential for regulation of mitosis , 1996, Nature.

[39]  E. Wilson,et al.  Identification of three proline-directed phosphorylation sites in the human androgen receptor. , 1995, Molecular endocrinology.

[40]  A. Brinkmann,et al.  Phosphotryptic peptide analysis of the human androgen receptor: detection of a hormone-induced phosphopeptide. , 1995, Biochemistry.

[41]  G. Jenster,et al.  Changes in the abundance of androgen receptor isotypes: effects of ligand treatment, glutamine-stretch variation, and mutation of putative phosphorylation sites. , 1994, Biochemistry.

[42]  H. Klocker,et al.  Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor and epidermal growth factor. , 1995, European urology.

[43]  J. Trapman,et al.  Localization and hormonal stimulation of phosphorylation sites in the LNCaP-cell androgen receptor. , 1993, The Biochemical journal.

[44]  P. Riegman,et al.  The promoter of the prostate-specific antigen gene contains a functional androgen responsive element. , 1991, Molecular endocrinology.

[45]  J. Trapman,et al.  Hormone-dependent androgen receptor phosphorylation is accompanied by receptor transformation in human lymph node carcinoma of the prostate cells. , 1991, The Journal of biological chemistry.

[46]  J. Trapman,et al.  Androgen receptor heterogeneity and phosphorylation in human LNCaP cells. , 1990, Biochemical and biophysical research communications.

[47]  M. Suzuki SPXX, a frequent sequence motif in gene regulatory proteins. , 1989, Journal of molecular biology.

[48]  M. Beato Gene regulation by steroid hormones , 1989, Cell.

[49]  H. Lilja A kallikrein-like serine protease in prostatic fluid cleaves the predominant seminal vesicle protein. , 1985, The Journal of clinical investigation.

[50]  A. Jemal,et al.  Cancer Statistics, 2005 , 2005, CA: a cancer journal for clinicians.