Chemistry and biological activities of Artemisia judaica: A mini review

Artemisia judaica L. is widely spread in the desert and coast of the Mediterranean region. Traditionally, it had been used as a vermifuge, stomachic, sedative, antispasmodic, diabetes, fungal infections and arthritis. It is strongly aromatic, with bushy herbs, woody bases and sturdy spreading branches, covered by woolly hairs, crowded and short leaves, heads are made of tubular florets. Recently, A. judaica gained attention around the world because of its therapeutic and biological activities such as anti-inflammatory, analgesic, anti-oxidant activity and high potential antiangiogenic activity. In this review, we summarize the most important chemical constituents and biological activities A. judaica.

[1]  H. Mohammed,et al.  Bio-Evaluation of the Wound Healing Activity of Artemisia judaica L. as Part of the Plant’s Use in Traditional Medicine; Phytochemical, Antioxidant, Anti-Inflammatory, and Antibiofilm Properties of the Plant’s Essential Oils , 2022, Antioxidants.

[2]  Rahamat Unissa,et al.  In-vitro Evaluation of Anti-microbial and Cytotoxic Activity of Artemisia judaica Leaves and Stem Extracts via Induction of Caspase Dependent Apoptosis , 2022, Indian Journal of Pharmaceutical Education and Research.

[3]  F. Moharram,et al.  Pharmacological activity and flavonoids constituents of Artemisia judaica L aerial parts. , 2021, Journal of ethnopharmacology.

[4]  Mahmoud A. Al-Qudah,et al.  Chemical composition and antioxidant activity of Jordanian Artemisia judaica L. as affected by different drying methods , 2021, International Journal of Food Properties.

[5]  S. M. Girgis,et al.  The Anticancer Activity of Artemisia Judaica Crude Extract in Human Hepatocellular Carcinoma HepG2 Cells by Induction of Apoptosis and Cell Cycle Arrest , 2021 .

[6]  A. Fahd,et al.  Cytotoxic, antimicrobial and antioxidant activities and phytochemical analysis of Artemisia judaica and A. sieberi in Saudi Arabia , 2020, African Journal of Pharmacy and Pharmacology.

[7]  R. Almeer,et al.  Protective effects of Artemisia judaica extract compared to metformin against hepatorenal injury in high-fat diet/streptozotocine-induced diabetic rats , 2020, Environmental Science and Pollution Research.

[8]  Mahmoud A. Al-Qudah,et al.  Effects of Artemisia judaica essential oil and ethanolic extract on experimentally-induced benign prostatic hyperplasia , 2020 .

[9]  A. Meena,et al.  Cirsimaritin, a lung squamous carcinoma cells (NCIH-520) proliferation inhibitor , 2020, Journal of biomolecular structure & dynamics.

[10]  G. Flamini,et al.  Chemical Composition, Antioxidant, Anti-Tyrosinase, Anti-Cholinesterase and Cytotoxic Activities of Essential Oils of Six Algerian Plants , 2020, Molecules.

[11]  Merajuddin Khan,et al.  Comparative study on the essential oils of Artemisia judaica and A. herba-alba from Saudi Arabia , 2020 .

[12]  M. Hegazy,et al.  Comparative chemical study and antimicrobial activity of essential oils of three Artemisia species from Egypt and Saudi Arabia , 2019, Flavour and Fragrance Journal.

[13]  Hari Prasad Devkota,et al.  Bioactive Compounds and Health Benefits of Artemisia Species , 2019, Natural Product Communications.

[14]  R. Ksouri,et al.  Phenolic Composition, Antioxidant, and Antibacterial Activities of Artemisia Judaica Subsp. Sahariensis , 2019, Journal of Herbs, Spices & Medicinal Plants.

[15]  P. Karanis,et al.  Anti-Blastocystis Activity In Vitro of Egyptian Herbal Extracts (Family: Asteraceae) with Emphasis on Artemisia judaica , 2019, International journal of environmental research and public health.

[16]  M. Ullah,et al.  Bioactive extract of Artemisia judaica causes in vitro inhibition of dipeptidyl peptidase IV and pancreatic/intestinal enzymes of the carbohydrate absorption cascade: implication for anti-diabetic new molecular entities (NMEs) , 2018, Oriental Pharmacy and Experimental Medicine.

[17]  H. Elansary,et al.  Effective antioxidant, antimicrobial and anticancer activities of essential oils of horticultural aromatic crops in northern Egypt , 2018, BMC Complementary and Alternative Medicine.

[18]  M. Shiboob,et al.  Antioxidant Activity of Phenolic and Alkaloid Fractions Accumulated in Artemisia Judaica and Artemisia Herba Alba , 2017 .

[19]  T. Shibamoto,et al.  Beneficial effects of a medicinal herb, Cirsium japonicum var. maackii, extract and its major component, cirsimaritin on breast cancer metastasis in MDA-MB-231 breast cancer cells. , 2017, Bioorganic & medicinal chemistry letters.

[20]  A. Osman,et al.  The genus Artemisia L. in the northern region of Saudi Arabia: essential oil variability and antibacterial activities , 2017, Natural product research.

[21]  T. Efferth,et al.  Chemical composition and biological activities of Artemisia judaica essential oil from southern desert of Jordan. , 2016, Journal of ethnopharmacology.

[22]  M. Akssira,et al.  Antimicrobial activity of essential oil of Artemisia judaica L. from Algeria against Multi‐Drug Resistant bacteria from clinical origin , 2016 .

[23]  C. Carrasco,et al.  Pro-apoptotic and anti-angiogenic properties of the α/β-thujone fraction from Thuja occidentalis on glioblastoma cells , 2016, Journal of Neuro-Oncology.

[24]  P. Marin,et al.  COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OILS OF ARTEMISIA JUDAICA, A. HERBA-ALBA AND A. ARBORESCENS FROM LIBYA , 2015 .

[25]  A. S. Othman,et al.  Antimicrobial Activity of Artemisinin and Precursor Derived from In Vitro Plantlets of Artemisia annua L. , 2014, BioMed research international.

[26]  H. Abd-Alla,et al.  Hunting for renal protective phytoconstituents in Artemisia judaica L. and Chrysanthemum coronarium L. (Asteraceae) , 2014 .

[27]  Hany Abdelhady.  Insecticidal activity and chemical composition of essential oil from Artemisia judaica L. against Callosobruchus maculatus (F.) (coleoptera: bruchidae) , 2012 .

[28]  F. Afifi,et al.  Screening the antiangiogenic activity of medicinal plants grown and sold in Jordan. , 2012, Planta medica.

[29]  M. Mahboubi,et al.  Antimicrobial activity and chemical composition of Mentha pulegium L. essential oil. , 2008, Journal of ethnopharmacology.

[30]  S. Abdelgaleil,et al.  Bioactivity of two major constituents isolated from the essential oil of Artemisia judaica L. , 2008, Bioresource technology.

[31]  Min-wei Wang,et al.  β-Eudesmol suppresses tumour growth through inhibition of tumour neovascularisation and tumour cell proliferation , 2008, Journal of Asian natural products research.

[32]  T. Dob,et al.  Chemical composition of the essential oil of Artemisia judaica L. from Algeria , 2006 .

[33]  Chunzhao Liu,et al.  Artemisia judaica L.: micropropagation and antioxidant activity. , 2004, Journal of biotechnology.

[34]  A. Farouk,et al.  Antioxidant activity and volatile components of Egyptian Artemisia judaica L. , 2002 .

[35]  I. A. Ross.  Medicinal Plants of the World , 2001, Humana Press.

[36]  K. H. Batanouny,et al.  Wild medicinal plants in Egypt : an inventory to support conservation and sustainable use , 1999 .

[37]  C. Zdero,et al.  Glaucolide-like sesquiterpene lactones from Artemisia judaica , 1988 .

[38]  M. A. Zarga,et al.  Effects of cirsimaritin, a flavone isolated from Artemisia judaica, on isolated guinea-pig ileum. , 1987, Planta medica.

[39]  M. Abou-zaid,et al.  Flavonoids of Artemisia judaica, A. Monosperma and A. herba-alba , 1987 .