IL-27 Limits IL-2 Production during Th1 Differentiation1
暂无分享,去创建一个
[1] M. Neurath,et al. Impaired Th1 responses in mice deficient in Epstein‐Barr virus‐induced gene 3 and challenged with physiological doses of Leishmania major , 2005, European journal of immunology.
[2] T. Mak,et al. The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis 1 , 2005, The Journal of Immunology.
[3] S. Khader,et al. IL-27 Signaling Compromises Control of Bacterial Growth in Mycobacteria-Infected Mice1 , 2004, The Journal of Immunology.
[4] G. Wu,et al. The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity1 , 2004, The Journal of Immunology.
[5] T. Yoshimoto,et al. An Indispensable Role for STAT1 in IL-27-Induced T-bet Expression but Not Proliferation of Naive CD4+ T Cells1 , 2004, The Journal of Immunology.
[6] C. Hunter,et al. Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27 , 2004, Arthritis research & therapy.
[7] C. Hunter,et al. Understanding the Pro- and Anti-Inflammatory Properties of IL-271 , 2004, The Journal of Immunology.
[8] C. Hunter,et al. Cutting Edge: Early IL-4 Production Governs the Requirement for IL-27-WSX-1 Signaling in the Development of Protective Th1 Cytokine Responses following Leishmania major Infection1 , 2004, The Journal of Immunology.
[9] R. Schwartz,et al. Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation1 , 2004, The Journal of Immunology.
[10] W. Alexander,et al. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. , 2004, Annual review of immunology.
[11] T. Mcclanahan,et al. WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27 , 2004, The Journal of Immunology.
[12] F. D. de Sauvage,et al. IL-27 regulates IL-12 responsiveness of naïve CD4+ T cells through Stat1-dependent and -independent mechanisms , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[13] S. Szabo,et al. Molecular mechanisms regulating Th1 immune responses. , 2003, Annual review of immunology.
[14] T. Mak,et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. , 2003, Immunity.
[15] G. Trinchieri,et al. The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. , 2003, Immunity.
[16] T. Mak,et al. WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. , 2003, Immunity.
[17] W. Paul,et al. Stat5 activation plays a critical role in Th2 differentiation. , 2003, Immunity.
[18] R. Kastelein,et al. IL-27 and IFN-α Signal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells , 2003 .
[19] S. Ebong,et al. Suppressor of Cytokine Signaling 3 Regulates Proliferation and Activation of T-helper Cells* , 2003, Journal of Biological Chemistry.
[20] J. Johnston,et al. SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses , 2003, Nature Medicine.
[21] R. Schwartz. T cell anergy. , 2003, Annual review of immunology.
[22] J. Johnston,et al. A Role of Suppressor of Cytokine Signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated Interleukin 2 Production , 2003, The Journal of experimental medicine.
[23] G. Trinchieri,et al. Interleukin-12 and the regulation of innate resistance and adaptive immunity , 2003, Nature Reviews Immunology.
[24] Ronald H. Schwartz,et al. Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process , 2003, Nature Immunology.
[25] U. Grohmann,et al. CTLA-4–Ig regulates tryptophan catabolism in vivo , 2002, Nature Immunology.
[26] C. Hunter,et al. Susceptibility of Interleukin-2-Deficient Mice to Toxoplasma gondii Is Associated with a Defect in the Production of Gamma Interferon , 2002, Infection and Immunity.
[27] D. Robinson,et al. Further checkpoints in Th1 development. , 2002, Immunity.
[28] T. Mcclanahan,et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. , 2002, Immunity.
[29] A. Sher,et al. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[30] X. Hua,et al. Cell cycle controlling the silencing and functioning of mammalian activators , 2001, Current Biology.
[31] T. Mak,et al. WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. , 2001, Immunity.
[32] S. Akira,et al. Cis3/Socs3/Ssi3 Plays a Negative Regulatory Role in Stat3 Activation and Intestinal Inflammation , 2001, The Journal of experimental medicine.
[33] T. Waldmann,et al. Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. , 2001, Immunity.
[34] R. Siegel,et al. The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity , 2000, Nature Immunology.
[35] F.J. Sauvage,et al. Development of Th1-type immune responses requires the type I cytokine receptor TCCR , 2000, Nature.
[36] H. Dickensheets,et al. Interleukin-12 differentially regulates expression of IFN-gamma and interleukin-2 in human T lymphoblasts. , 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[37] J. G. Zhang,et al. Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[38] Laurie H Glimcher,et al. A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment , 2000, Cell.
[39] S. Akira,et al. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. , 1998, Journal of immunology.
[40] P. Heinrich,et al. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. , 1998, The Biochemical journal.
[41] Werner Müller,et al. Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation. , 1998, International immunology.
[42] Chyung-Ru Wang,et al. Helper T cell differentiation is controlled by the cell cycle. , 1998, Immunity.
[43] M. Karin,et al. Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway. , 1998, Science.
[44] J. Tschopp,et al. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. , 1998, Immunity.
[45] A. Khoruts,et al. A Natural Immunological Adjuvant Enhances T Cell Clonal Expansion through a CD28-dependent, Interleukin (IL)-2–independent Mechanism , 1998, The Journal of experimental medicine.
[46] H. Gudmundsdottir,et al. Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response. , 1997, The Journal of clinical investigation.
[47] S. Szabo,et al. Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells , 1997, The Journal of experimental medicine.
[48] D. Carvajal,et al. IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses , 1996 .
[49] C. Hunter,et al. Roles of gamma interferon and other cytokines in suppression of the spleen cell proliferative response to concanavalin A and toxoplasma antigen during acute toxoplasmosis , 1995, Infection and immunity.
[50] R. Seder. Acquisition of lymphokine-producing phenotype by CD4+ T cells. , 1994, The Journal of allergy and clinical immunology.
[51] T. Mosmann,et al. Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. , 1994, Journal of immunology.
[52] C Anasetti,et al. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1 , 1993, The Journal of experimental medicine.
[53] R. Schwartz. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy , 1992, Cell.
[54] A. Sher,et al. Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. , 1991, Journal of immunology.
[55] F. Dumont,et al. The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. , 1989, Journal of immunology.
[56] Kendall A. Smith,et al. Interleukin-2: inception, impact, and implications. , 1988, Science.
[57] D. Baltimore,et al. T-cell-specific expression of interleukin 2: evidence for a negative regulatory site. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[58] B. Luft,et al. Demonstration of T-cell dysfunction during acute toxoplasma infection. , 1986, Cellular immunology.
[59] V. Paetkau,et al. Induction of interleukin 2 messenger RNA inhibited by cyclosporin A. , 1984, Science.
[60] S. Efrat,et al. Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[61] 武田 篤信. Cutting edge : Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment , 2003 .
[62] A. Khoruts,et al. In vivo activation of antigen-specific CD4 T cells. , 2001, Annual review of immunology.
[63] T. Kishimoto,et al. Gp130 and the interleukin-6 family of cytokines. , 1997, Annual review of immunology.
[64] K. Takakura,et al. [Interleukin-2 receptor]. , 1997, Nihon rinsho. Japanese journal of clinical medicine.
[65] A. Rao,et al. Transcriptional regulation of the IL-2 gene. , 1995, Current opinion in immunology.
[66] W. Paul,et al. Acquisition of lymphokine-producing phenotype by CD4+ T cells. , 1994, Annual review of immunology.