Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM.

[1]  M. Caligiuri,et al.  Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses , 2006, Proceedings of the National Academy of Sciences.

[2]  S. Yang,et al.  Temozolomide Chemotherapy in Patients with Recurrent Malignant Gliomas , 2006, Journal of Korean medical science.

[3]  Susan M. Chang,et al.  Standard treatment and experimental targeted drug therapy for recurrent glioblastoma multiforme. , 2006, Neurosurgical focus.

[4]  R. Martuza,et al.  Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. , 2006, Journal of the National Cancer Institute.

[5]  Martin J. van den Bent,et al.  Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. , 2005, The New England journal of medicine.

[6]  R. Mirimanoff,et al.  MGMT gene silencing and benefit from temozolomide in glioblastoma. , 2005, The New England journal of medicine.

[7]  J. Olson,et al.  A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

[8]  S. Brown,et al.  HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival , 2004, Gene Therapy.

[9]  P. Meylan,et al.  Bmc Infectious Diseases Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Western and Southern Switzerland in Adults Aged 25–74 in 1992–93 : a Population-based Study , 2022 .

[10]  M. Chamberlain,et al.  Salvage Chemotherapy with Taxol for Recurrent Anaplastic Astrocytomas , 1999, Journal of Neuro-Oncology.

[11]  H. Doerr,et al.  Seroprevalence of herpes simplex virus types 1 and type 2 in the Frankfurt am Main area, Germany , 2002, Medical Microbiology and Immunology.

[12]  E. A. Chiocca,et al.  Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study. , 2000, Journal of neurosurgery.

[13]  R. Martuza,et al.  Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial , 2000, Gene Therapy.

[14]  R. Martuza,et al.  Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice , 2000, Journal of Virology.

[15]  J. Markert,et al.  Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[16]  R. Weichselbaum,et al.  Genetically engineered HSV in the treatment of glioma: a review , 2000, Reviews in medical virology.

[17]  R. Martuza,et al.  Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. , 1999, Human gene therapy.

[18]  R. Martuza,et al.  Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation of Intracerebral Injection in Nonhuman Primates , 1999, Journal of Virology.

[19]  D. Kondziolka,et al.  Morbidity and survival after 1,3-bis(2-chloroethyl)-1-nitrosourea wafer implantation for recurrent glioblastoma: a retrospective case-matched cohort series. , 1999, Neurosurgery.

[20]  M. Chamberlain,et al.  Salvage chemotherapy with tamoxifen for recurrent anaplastic astrocytomas. , 1999, Archives of neurology.

[21]  J. Markert,et al.  Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[22]  R. Martuza,et al.  Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. , 1999, Human gene therapy.

[23]  S. Inouye,et al.  Changes in Prevalence of Herpes Simplex Virus Type 1 and 2 Antibodies from 1973 to 1993 in the Rural Districts of Japan , 1999, Microbiology and immunology.

[24]  R. Martuza,et al.  In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activity. , 1998, Journal of immunology.

[25]  D. Hallahan,et al.  Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors , 1998, Gene Therapy.

[26]  Z. Ram,et al.  Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells , 1997, Nature Medicine.

[27]  R. Martuza,et al.  Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1. , 1995, Cancer research.

[28]  R. Martuza,et al.  Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas , 1995, Nature Medicine.

[29]  S. Rabkin,et al.  CNS tumor therapy by attenuated herpes simplex viruses. , 1994, Gene therapy.

[30]  R. Martuza,et al.  Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir. , 1993, Neurosurgery.

[31]  M. Prados,et al.  Highly anaplastic astrocytoma: a review of 357 patients treated between 1977 and 1989. , 1992, International journal of radiation oncology, biology, physics.

[32]  D M Coen,et al.  Experimental therapy of human glioma by means of a genetically engineered virus mutant , 1991, Science.

[33]  P. Gutin,et al.  Development of multiple lesions during radiation therapy and chemotherapy in patients with gliomas. , 1986, Journal of neurosurgery.

[34]  D P Byar,et al.  Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. , 1980, The New England journal of medicine.

[35]  B. Pasquier,et al.  Extraneural metastases of astrocytomas and glioblastomas clinicopathological study of two cases and review of literature , 1980, Cancer.