Activation–threshold tuning in an affinity model for the T–cell repertoire
暂无分享,去创建一个
[1] A S Perelson,et al. Explaining high alloreactivity as a quantitative consequence of affinity-driven thymocyte selection. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[2] Z. Grossman,et al. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[3] J. Sprent,et al. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. , 1999, Immunity.
[4] E. Ward,et al. Negative Selection during the Peripheral Immune Response to Antigen , 2001, The Journal of experimental medicine.
[5] M. Tomkowiak,et al. Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivo. , 1998, Journal of immunology.
[6] A. Perelson,et al. How diverse should the immune system be? , 1993, Proceedings of the Royal Society of London. Series B: Biological Sciences.
[7] P. Kourilsky,et al. Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion. , 2000, Immunity.
[8] S. Marguerat,et al. Quantitative Impact of Thymic Clonal Deletion on the T Cell Repertoire , 1997, The Journal of experimental medicine.
[9] M. Purbhoo,et al. Sensory Adaptation in Naive Peripheral CD4 T Cells , 2001, The Journal of experimental medicine.
[10] T. K. Carne. The Geometry of Shape Spaces , 1990 .
[11] J. Borghans,et al. Memorizing innate instructions requires a sufficiently specific adaptive immune system. , 2002, International immunology.
[12] M. Cohn,et al. The E-T (elephant-tadpole) paradox necessitates the concept of a unit of B-cell function: the protection. , 1987, Molecular immunology.
[13] A S Perelson,et al. The paradox of alloreactivity and self MHC restriction: quantitative analysis and statistics. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[14] J. Whitton,et al. Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR , 2001, Nature Immunology.
[15] G. Oster,et al. Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination. , 1979, Journal of theoretical biology.
[16] Philippa Marrack,et al. Negative selection imparts peptide specificity to the mature T cell repertoire , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[17] S. Tonegawa,et al. A differential-avidity model for T-cell selection. , 1994, Immunology today.
[18] Z. Grossman,et al. Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[19] L. Nicholson,et al. Tuning T cell activation threshold and effector function with cross-reactive peptide ligands. , 2000, International immunology.
[20] J. Kappler,et al. T Cell Receptor (Tcr)-Mediated Repertoire Selection and Loss of Tcr Vβ Diversity during the Initiation of a Cd4+ T Cell Response in Vivo , 2000, The Journal of experimental medicine.
[21] D A Rand,et al. A reliable and safe T cell repertoire based on low-affinity T cell receptors. , 2001, Journal of theoretical biology.
[22] A S Perelson,et al. Deriving Quantitative Constraints on T Cell Selection from Data on the Mature T Cell Repertoire1 , 2000, The Journal of Immunology.
[23] R. Boyd,et al. Agonist peptide modulates T cell selection thresholds through qualitative and quantitative shifts in CD8 co-receptor expression. , 1997, International immunology.
[24] S. Jameson,et al. Preselection Thymocytes Are More Sensitive to T Cell Receptor Stimulation Than Mature T Cells , 1998, The Journal of experimental medicine.
[25] A S Perelson,et al. Variable efficacy of repeated annual influenza vaccination. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[26] A. Perelson,et al. Size and connectivity as emergent properties of a developing immune network. , 1991, Journal of theoretical biology.
[27] D. Busch,et al. T Cell Affinity Maturation by Selective Expansion during Infection , 1999, The Journal of experimental medicine.
[28] A. Rudensky,et al. Dynamic Tuning of T Cell Reactivity by Self-Peptide–Major Histocompatibility Complex Ligands , 2001, The Journal of experimental medicine.
[29] R. Boyd,et al. Positive selection of low responsive, potentially autoreactive T cells induced by high avidity, non-deleting interactions. , 1998, International immunology.
[30] Xiping Wei,et al. Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus , 1997, Nature Medicine.
[31] Ron R. Hightower,et al. Deriving shape space parameters from immunological data. , 1997, Journal of theoretical biology.
[32] R. Germain,et al. Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire. , 1999, Immunity.
[33] A. Perelson,et al. Size and connectivity of the idiotypic network are independent of the discreteness of the affinity distribution. , 1996, Journal of theoretical biology.
[34] A. Noest,et al. How specific should immunological memory be? , 1999, Journal of immunology.
[35] R. Henderson,et al. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. , 1992, Science.
[36] Eric G. Pamer,et al. Evolution of a Complex T Cell Receptor Repertoire during Primary and Recall Bacterial Infection , 1998, The Journal of experimental medicine.
[37] D. Wraith,et al. Selection and fine-tuning of the autoimmune T-cell repertoire , 2002, Nature Reviews Immunology.
[38] Daniel C. Douek,et al. A Novel Approach to the Analysis of Specificity, Clonality, and Frequency of HIV-Specific T Cell Responses Reveals a Potential Mechanism for Control of Viral Escape1 , 2002, The Journal of Immunology.
[39] A. Casrouge,et al. Diversity of Human alpha beta T Cell Receptors , 2000, Science.
[40] Z. Grossman,et al. Self-tolerance: context dependent tuning of T cell antigen recognition. , 2000, Seminars in immunology.
[41] A. Noest,et al. Designing lymphocyte functional structure for optimal signal detection: voilà, T cells. , 2000, Journal of theoretical biology.
[42] Rustom Antia,et al. Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells , 2002, The Journal of experimental medicine.
[43] A S Perelson,et al. A quantitative theory of affinity-driven T cell repertoire selection. , 1999, Journal of theoretical biology.
[44] Philippa Marrack,et al. T cells down-modulate peptide-MHC complexes on APCs in vivo , 2002, Nature Immunology.
[45] J. Robert,et al. B‐cell development in the amphibian Xenopus , 2000, Immunological reviews.
[46] R Farber,et al. The geometry of shape space: application to influenza. , 2001, Journal of theoretical biology.
[47] J. Borghans,et al. Diversity of Human αβ T Cell Receptors , 2000 .