Wharton's jelly MSC-derived extracellular vehicles—loaded hyaluronic acid-alginate adhesives for treatment of osteoarthritis

[1]  G. Xiao,et al.  Current understanding of osteoarthritis pathogenesis and relevant new approaches , 2022, Bone Research.

[2]  D. Primorac,et al.  Mesenchymal Stem Cell Mechanisms of Action and Clinical Effects in Osteoarthritis: A Narrative Review , 2022, Genes.

[3]  Xiao Zhang,et al.  Exosomes derived from hypoxia preconditioned mesenchymal stem cells laden in a silk hydrogel promote cartilage regeneration via the miR-205-5p/PTEN/AKT pathway. , 2022, Acta biomaterialia.

[4]  G. Xiao,et al.  Kindlin-2 preserves integrity of the articular cartilage to protect against osteoarthritis , 2021, Nature Aging.

[5]  Zheng Chen,et al.  Exosome-loaded extracellular matrix-mimic hydrogel with anti-inflammatory property Facilitates/promotes growth plate injury repair , 2021, Bioactive materials.

[6]  M. Lee,et al.  TGFβ1-Induced Transglutaminase-2 Triggers Catabolic Response in Osteoarthritic Chondrocytes by Modulating MMP-13 , 2021, Tissue Engineering and Regenerative Medicine.

[7]  M. Ecker,et al.  Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis , 2021, International journal of molecular sciences.

[8]  H. Ouyang,et al.  Advanced hydrogels for the repair of cartilage defects and regeneration , 2020, Bioactive materials.

[9]  K. Shah,et al.  Mesenchymal Stem Cell Immunomodulation: Mechanisms and Therapeutic Potential. , 2020, Trends in pharmacological sciences.

[10]  L. Rong,et al.  Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis , 2020, Stem Cell Research & Therapy.

[11]  Ilker S. Bayer Hyaluronic Acid and Controlled Release: A Review , 2020, Molecules.

[12]  Zhe Jin,et al.  Exosomal miR-9-5p secreted by bone marrow–derived mesenchymal stem cells alleviates osteoarthritis by inhibiting syndecan-1 , 2020, Cell and Tissue Research.

[13]  Biao Zhu,et al.  Integration of Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes with Hydroxyapatite-Embedded Hyaluronic Acid-Alginate Hydrogel for Bone Regeneration. , 2020, ACS biomaterials science & engineering.

[14]  X. Mo,et al.  In situ forming hydrogel of natural polysaccharides through Schiff base reaction for soft tissue adhesive and hemostasis. , 2020, International journal of biological macromolecules.

[15]  F. Lv,et al.  miR-23a-3p-abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration , 2020, Journal of extracellular vesicles.

[16]  Guanwei Fan,et al.  Co-administration of an adhesive conductive hydrogel patch and an injectable hydrogel to treat myocardial infarction. , 2019, ACS applied materials & interfaces.

[17]  B. Lei,et al.  Efficient Angiogenesis-Based Diabetic Wound Healing/Skin Reconstruction through Bioactive Antibacterial Adhesive Ultra-Violet Shielding Nanodressing with Exosome Release. , 2019, ACS nano.

[18]  Jianting Chen,et al.  Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression , 2019, Redox biology.

[19]  Xin-long Ma,et al.  Exosomes derived from Wharton's jelly of human umbilical cord mesenchymal stem cells reduce osteocyte apoptosis in glucocorticoid-induced osteonecrosis of the femoral head in rats via the miR-21-PTEN-AKT signalling pathway , 2019, International journal of biological sciences.

[20]  Guanwei Fan,et al.  Conductive Hydrogen Sulfide-Releasing Hydrogel Encapsulating ADSCs for Myocardial Infarction Treatment. , 2019, ACS applied materials & interfaces.

[21]  D. Surbek,et al.  Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury , 2019, Stem Cell Research & Therapy.

[22]  C. Yeh,et al.  Enhancing Microcirculation on Multitriggering Manner Facilitates Angiogenesis and Collagen Deposition on Wound Healing by Photoreleased NO from Hemin-Derivatized Colloids. , 2019, ACS nano.

[23]  S. Lim,et al.  MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis. , 2019, Biomaterials.

[24]  M. Chopp,et al.  Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury , 2019, Nature Reviews Neurology.

[25]  H. Ni,et al.  Luteolin inhibits IL-1β-induced inflammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[26]  M. Goldring,et al.  Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy , 2018, Annals of the New York Academy of Sciences.

[27]  P. Sajkiewicz,et al.  Injectable hydrogels and nanocomposite hydrogels for cartilage regeneration. , 2018, Journal of biomedical materials research. Part A.

[28]  N. Bakhtyar,et al.  Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing , 2018, Stem Cell Research & Therapy.

[29]  Inge Fristad,et al.  Adipose-derived and bone marrow mesenchymal stem cells: a donor-matched comparison , 2018, Stem Cell Research & Therapy.

[30]  M. Alcaraz,et al.  Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes , 2018, Cellular Physiology and Biochemistry.

[31]  A. Boccaccini,et al.  Oxidized Alginate-Based Hydrogels for Tissue Engineering Applications: A Review. , 2018, Biomacromolecules.

[32]  D. Saris,et al.  Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro , 2018, Theranostics.

[33]  D. Hunter,et al.  Intra-articular therapies for osteoarthritis , 2016, Expert opinion on pharmacotherapy.

[34]  Gwo‐Jaw Wang,et al.  Parathyroid hormone 1-34 reduces dexamethasone-induced terminal differentiation in human articular chondrocytes. , 2016, Toxicology.

[35]  C. Henrionnet,et al.  Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering , 2015, Stem Cell Research & Therapy.

[36]  Gui-quan Cai,et al.  Autophagy protects chondrocytes from glucocorticoids-induced apoptosis via ROS/Akt/FOXO3 signaling. , 2015, Osteoarthritis and cartilage.

[37]  H. Hwang,et al.  Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis , 2015, International journal of molecular sciences.

[38]  A. Gelber,et al.  Osteoarthritis , 2020, Annals of Internal Medicine.

[39]  Farshid Guilak,et al.  Composite Three‐Dimensional Woven Scaffolds with Interpenetrating Network Hydrogels to Create Functional Synthetic Articular Cartilage , 2013, Advanced functional materials.

[40]  G. Prestwich Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[41]  A. Lowman,et al.  Hydrogels for the repair of articular cartilage defects. , 2011, Tissue engineering. Part B, Reviews.

[42]  Kozo Nakamura,et al.  Osteoarthritis development in novel experimental mouse models induced by knee joint instability. , 2005, Osteoarthritis and cartilage.

[43]  M D McKee,et al.  Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. , 2005, Osteoarthritis and cartilage.

[44]  A. Steensberg,et al.  IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans. , 2003, American journal of physiology. Endocrinology and metabolism.