Humidification performance of 48 passive airway humidifiers: comparison with manufacturer data.

INTRODUCTION Heat and moisture exchangers (HMEs) are increasingly used in the ICU for gas conditioning during mechanical ventilation. Independent assessments of the humidification performance of HMEs are scarce. The aim of the present study was thus to assess the humidification performance of a large number of adult HMEs. METHOD We assessed 48 devices using a bench test apparatus that simulated real-life physiologic ventilation conditions. Thirty-two devices were described by the manufacturers as HMEs, and 16 were described as antibacterial filters. The test apparatus provided expiratory gases with an absolute humidity (AH) of 35 mg H(2)O/L. The AH of inspired gases was measured after steady state using the psychrometric method. We performed three hygrometric measurements for each device, measured their resistance, and compared our results with the manufacturer data. RESULTS Of the 32 HMEs tested, only 37.5% performed well (>or= 30 mg H(2)O/L), while 25% performed poorly (< 25 mg H(2)O/L). The mean difference (+/- SD) between our measurements and the manufacturer data was 3.0 +/- 2.7 mg H(2)O/L for devices described as HMEs (maximum, 8.9 mg H(2)O/L) [p = 0.0001], while the mean difference for 36% of the HMEs was > 4 mg H(2)O/L. The mean difference for the antibacterial filters was 0.2 +/- 1.4 mg H(2)O/L. The mean resistance of all the tested devices was 2.17 +/- 0.70 cm H(2)O/L/s. CONCLUSIONS Several HMEs performed poorly and should not be used as HMEs. The values determined by independent assessments may be lower than the manufacturer data. Describing a device as an HME does not guarantee that it provides adequate humidification. The performance of HMEs must be verified by independent assessment.

[1]  Arthur S Slutsky,et al.  Weaning critically ill adults from invasive mechanical ventilation: a national survey , 2009, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[2]  H. Bruining,et al.  A novel method of evaluation of three heat-moisture exchangers in six different ventilator settings , 1998, Intensive Care Medicine.

[3]  L. Brochard,et al.  Under-humidification and over-humidification during moderate induced hypothermia with usual devices , 2006, Intensive Care Medicine.

[4]  R. Heller,et al.  Double-heater-wire circuits and heat-and-moisture exchangers and the risk of ventilator-associated pneumonia , 2006, Critical care medicine.

[5]  L. Brochard,et al.  Impact of humidification systems on ventilator-associated pneumonia: a randomized multicenter trial. , 2005, American journal of respiratory and critical care medicine.

[6]  H. Bruining,et al.  An experimental set-up to test heatmoisture exchangers , 1995, Intensive Care Medicine.

[7]  A. R. Webb,et al.  An evaluation of the heat and moisture exchange performance of four ventilator circuit filters , 2005, Intensive Care Medicine.

[8]  J. Roustan,et al.  Comparison of hydrophobic heat and moisture exchangers with heated humidifier during prolonged mechanical ventilation , 2005, Intensive Care Medicine.

[9]  François Lellouche,et al.  Influence of ambient and ventilator output temperatures on performance of heated-wire humidifiers. , 2004, American journal of respiratory and critical care medicine.

[10]  S. Jaber,et al.  Long-term Effects of Different Humidification Systems on Endotracheal Tube Patency: Evaluation by the Acoustic Reflection Method , 2004, Anesthesiology.

[11]  A. Boyer,et al.  Heat and moisture exchangers in mechanically ventilated intensive care unit patients: A plea for an independent assessment of their performance , 2003, Critical care medicine.

[12]  D. Cook,et al.  Physicians' attitude to use heat and moisture exchangers or heated humidifiers: a Franco-Canadian survey , 2002, Intensive Care Medicine.

[13]  L. Thomachot,et al.  Randomized clinical trial of extended use of a hydrophobic condenser humidifier: 1 vs. 7 days , 2002, Critical care medicine.

[14]  E. N. Kapadia Factors associated with blocked tracheal tubes , 2001, Intensive Care Medicine.

[15]  D. Dreyfuss,et al.  Safety, efficacy, and cost‐effectiveness of mechanical ventilation with humidifying filters changed every 48 hours: A prospective, randomized study , 2000, Critical care medicine.

[16]  B. Paluch Efficiency and safety of mechanical ventilation with a heat and moisture exchanger changed only once a week , 2000 .

[17]  D. Dreyfuss,et al.  Efficiency and safety of mechanical ventilation with a heat and moisture exchanger changed only once a week. , 2000, American journal of respiratory and critical care medicine.

[18]  C. Martin,et al.  Changing a hydrophobic heat and moisture exchanger after 48 hours rather than 24 hours: a clinical and microbiological evaluation , 1999, Intensive Care Medicine.

[19]  D. Dreyfuss,et al.  Bedside evaluation of efficient airway humidification during mechanical ventilation of the critically ill. , 1999, Chest.

[20]  C. Martin,et al.  Do the components of heat and moisture exchanger filters affect their humidifying efficacy and the incidence of nosocomial pneumonia? , 1999, Critical care medicine.

[21]  C. Martin,et al.  Comparing two heat and moisture exchangers, one hydrophobic and one hygroscopic, on humidifying efficacy and the rate of nosocomial pneumonia. , 1998, Chest.

[22]  M. Kollef,et al.  A randomized clinical trial comparing an extended-use hygroscopic condenser humidifier with heated-water humidification in mechanically ventilated patients. , 1998, Chest.

[23]  C. Martin,et al.  Efficacy of heat and moisture exchangers after changing every 48 hours rather than 24 hours. , 1998, Critical care medicine.

[24]  O. Kirton,et al.  A prospective, randomized comparison of an in-line heat moisture exchange filter and heated wire humidifiers: rates of ventilator-associated early-onset (community-acquired) or late-onset (hospital-acquired) pneumonia and incidence of endotracheal tube occlusion. , 1997, Chest.

[25]  C. Perret,et al.  Safety of combined heat and moisture exchanger filters in long-term mechanical ventilation. , 1997, Chest.

[26]  R. Boots,et al.  Clinical utility of hygroscopic heat and moisture exchangers in intensive care patients. , 1997, Critical care medicine.

[27]  L. Brochard,et al.  Gradual Reduction of Endotracheal Tube Diameter during Mechanical Ventilation via Different Humidification Devices , 1996, Anesthesiology.

[28]  R. Branson,et al.  Evaluation of 21 passive humidifiers according to the ISO 9360 standard : Moisture output, dead space, and flow resistance , 1996 .

[29]  X Viviand,et al.  Comparing two heat and moisture exchangers with one vaporizing humidifier in patients with minute ventilation greater than 10 L/min. , 1995, Chest.

[30]  Y. Cohen,et al.  Mechanical ventilation with heated humidifiers or heat and moisture exchangers: effects on patient colonization and incidence of nosocomial pneumonia. , 1995, American journal of respiratory and critical care medicine.

[31]  J. Verhoef,et al.  Bacterial and viral removal efficiency, heat and moisture exchange properties of four filtration devices. , 1995, The Journal of hospital infection.

[32]  L. Papazian,et al.  Preservation of humidity and heat of respiratory gases in patients with a minute ventilation greater than 10 L/min , 1994, Critical care medicine.

[33]  R. Branson,et al.  Humidification in the intensive care unit. Prospective study of a new protocol utilizing heated humidification and a hygroscopic condenser humidifier. , 1993, Chest.

[34]  L. Papazian,et al.  Performance evaluation of three vaporizing humidifiers and two heat and moisture exchangers in patients with minute ventilation > 10 L/min. , 1992, Chest.

[35]  C. Mebius Heat and moisture exchangers with bacterial filters: a laboratory evaluation , 1992, Acta anaesthesiologica Scandinavica.

[36]  AARC clinical practice guideline. Humidification during mechanical ventilation. American Association for Respiratory Care. , 1992, Respiratory care.

[37]  B. Escudier,et al.  Heat and moisture exchanger vs heated humidifier during long-term mechanical ventilation. A prospective randomized study. , 1991, Chest.

[38]  B. Eckerbom,et al.  Performance evaluation of six heat and moisture exchangers according to the Draft International Standard (ISO/DIS 9360) , 1990, Acta anaesthesiologica Scandinavica.

[39]  G. Perrin,et al.  Heat and moisture exchangers and vaporizing humidifiers in the intensive care unit. , 1990, Chest.

[40]  I. L. Cohen,et al.  Endotracheal tube occlusion associated with the use of heat and moisture exchangers in the intensive care unit. , 1988, Critical care medicine.

[41]  M. Turtle,et al.  An Evaluation of Six Disposable Heat and Moisture Exchangers , 1987, Anaesthesia and intensive care.

[42]  R. Latimer,et al.  A comparison of five heat and moisture exchangers , 1986, Anaesthesia.

[43]  F. Mannino,et al.  Moisture‐conserving efficiency of condenser humidifiers * , 1985, Anaesthesia.

[44]  H. Turndorf,et al.  The Pall Ultipor Breathing Circuit Filter—An Efficient Heat and Moisture Exchanger , 1984, Anesthesia and analgesia.

[45]  C. Membius A Comparative Evaluation of Disposable Humidifiers , 1983 .

[46]  D. B. Weeks,et al.  Laboratory Investigation of Six Artificial Noses for Use during Endotracheal Anesthesia , 1983, Anesthesia and analgesia.

[47]  C. Mebius A comparative evaluation of disposable humidifiers. , 1983, Acta anaesthesiologica Scandinavica.

[48]  A Gedeon,et al.  The Hygroscopic Condenser Humidifier A new device for general use in anaesthesia and intensive care , 1979, Anaesthesia.

[49]  D. Bethune,et al.  A comparative study of condenser humidifiers , 1976, Anaesthesia.

[50]  R. Déry The evolution of heat and moisture in the respiratory tract during anaesthesia with a non-rebreathing system , 1973, Canadian Anaesthetists' Society journal.

[51]  R. Déry,et al.  Humidity in anaesthesiology III. Heat and moisture patterns in the respiratory tract during anaesthesia with the semi-closed system , 1967, Canadian Anaesthetists' Society journal.

[52]  J. Burton effect of DRY ANAESTHETIC GASES on the RESPIRATORY MUCOUS MEMBRANE , 1962 .

[53]  J. Burton Effects of dry anaesthetic gases on the respiratory mucous membrane. , 1962, Lancet.